scholarly journals Strategy to design a smart photocleavable and pH sensitive chitosan based hydrogel through a novel crosslinker: a potential vehicle for controlled drug delivery

RSC Advances ◽  
2020 ◽  
Vol 10 (25) ◽  
pp. 14694-14704 ◽  
Author(s):  
Safiya Nisar ◽  
Ashiq Hussain Pandit ◽  
Li-Fang Wang ◽  
Sunita Rattan

We report the synthesis of a novel photocleavable crosslinker and its joining with amine-based polysachharides, viz. chitosan, resulting in the formation of a dual stimuli-responsive hydrogel having UV- and pH-responsive sites.

RSC Advances ◽  
2016 ◽  
Vol 6 (6) ◽  
pp. 4850-4857 ◽  
Author(s):  
Xue Jiao Liu ◽  
Hai Qiang Li ◽  
Bao Yuan Zhang ◽  
Ya Jun Wang ◽  
Xiu Yan Ren ◽  
...  

Stimuli-responsive hydrogels are becoming increasingly important for controlled drug delivery, biosensing, and tissue engineering. It would be much advantageous for intelligent hydrogels if they exhibit superior mechanical performances.


RSC Advances ◽  
2020 ◽  
Vol 10 (46) ◽  
pp. 27305-27314
Author(s):  
Yolanda Salinas ◽  
Michael Kneidinger ◽  
Cristina Fornaguera ◽  
Salvador Borrós ◽  
Oliver Brüggemann ◽  
...  

Bottle-brush polyphosphazenes as dual, thermosensitive and pH responsive gatekeepers for mesoporous silica nanoparticles, and their use in controlled drug release.


RSC Advances ◽  
2017 ◽  
Vol 7 (5) ◽  
pp. 2829-2835 ◽  
Author(s):  
Huan Huang ◽  
Ping Li ◽  
Changliang Liu ◽  
Huailei Ma ◽  
He Huang ◽  
...  

Metal ions/polyphenol complexes encapsulated paclitaxel nanodrug with high pH-sensitive drug release property and enhanced antitumor activity was obtained.


2020 ◽  
Author(s):  
Stephanie Farrell ◽  
Jennifer Vernengo ◽  
Madina Yermagambetova ◽  
Peter Schwalbenberg

2014 ◽  
Vol 2 (38) ◽  
pp. 6580-6589 ◽  
Author(s):  
Hao-Syun Chou ◽  
Meng-Hsuan Hsiao ◽  
Wei-Yang Hung ◽  
Tin-Yo Yen ◽  
Hui-Yi Lin ◽  
...  

A new type of CHC–PY core–shell nanoparticle provides multiple functionality, where a synergistic performance of nanotherapeutics, imaging and even diagnosis at a cellular resolution can be achieved simultaneously.


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