Bottom-up design of model network elastomers and hydrogels from precise star polymers

2019 ◽  
Vol 10 (27) ◽  
pp. 3740-3750 ◽  
Author(s):  
Guido Creusen ◽  
Ardeshir Roshanasan ◽  
Javier Garcia Lopez ◽  
Kalina Peneva ◽  
Andreas Walther
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Star Polymers ◽  
Water Soluble ◽  
Bottom Up ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Model Network

Well-defined high-molecular weight star polymers based on low-Tg water-soluble polymers enable bottom-up design of model network elastomers and functional hydrogels.

Synthetic Polymers in Water-in-Oil Microemulsions

1989 ◽  
Vol 171 ◽  
Author(s):  
Francoise Candau
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Reverse Micelles ◽  
Synthetic Polymers ◽  
Water Soluble ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Low Viscosity ◽  
Oil Emulsions ◽  
Stable Particles

ABSTRACTHigh molecular weight water-soluble polymers are usually supplied in the form of water-in-oil emulsions which have advantages of low viscosity and easy storage and dissolution. Most uses in water treatment, flocculation, paper manufacture or mining fields require polymer latexes formed of finely dipersed particles. Polymerization in reverse micelles or microemulsions appears to be an attractive technique because it can lead, under appropriate formulations, to high molecular weight polymers entrapped within small-sized stable particles. The main characteristics and properties of the latexes and polymers formed by this process are described.

β-Glycosylamide Glycopolymers: Synthesis, Physical Properties, Chemical and Enzymatic Stability

1995 ◽  
Vol 394 ◽  
Author(s):  
Wayne Spevak ◽  
Frangois D. Tropper
Keyword(s):  
Molecular Weight ◽  
Physical Properties ◽  
Water Soluble ◽  
Glycosidic Linkage ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Enzymatic Stability ◽  
Reducing Carbohydrates

AbstractA method is described for the preparation β-glycosylamide monomers from reducing carbohydrates. The glycosylamide monomers were copolymerized with acrylamide to formhigh molecular weight, water soluble polymers. The chemical and enzymatic stability of the β-N-glycosidic linkage was investigated. In addition, the glycopolymers were characterized by their interactions with lectins.

scholarly journals Macromolecular Systems for Vaccine Delivery

2016 ◽  
pp. S203-S216 ◽  
Author(s):  
G. MUŽÍKOVÁ ◽  
R. LAGA
Keyword(s):  
Molecular Weight ◽  
Infectious Diseases ◽  
Human Medicine ◽  
Water Soluble ◽  
Water Soluble Polymers ◽  
Soluble Polymers ◽  
Cell Responses ◽  
Macromolecular Systems ◽  
Protective Antibodies ◽  
Life Threatening

Vaccines have helped considerably in eliminating some life-threatening infectious diseases in past two hundred years. Recently, human medicine has focused on vaccination against some of the world’s most common infectious diseases (AIDS, malaria, tuberculosis, etc.), and vaccination is also gaining popularity in the treatment of cancer or autoimmune diseases. The major limitation of current vaccines lies in their poor ability to generate a sufficient level of protective antibodies and T cell responses against diseases such as HIV, malaria, tuberculosis and cancers. Among the promising vaccination systems that could improve the potency of weakly immunogenic vaccines belong macromolecular carriers (water soluble polymers, polymer particels, micelles, gels etc.) conjugated with antigens and immunistumulatory molecules. The size, architecture, and the composition of the high molecular-weight carrier can significantly improve the vaccine efficiency. This review includes the most recently developed (bio)polymer-based vaccines reported in the literature.

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