The synergistic effect of Au-COF nanosheets and artificial peroxidase Au@ZIF-8(NiPd) rhombic dodecahedra for signal amplification for biomarker detection

Nanoscale ◽  
2019 ◽  
Vol 11 (42) ◽  
pp. 20221-20227 ◽  
Author(s):  
Tingting Zhang ◽  
Yu Song ◽  
Yue Xing ◽  
Yue Gu ◽  
Xiaoyi Yan ◽  
...  
Keyword(s):  
Synergistic Effect ◽  
Electrochemical Sensor ◽  
Signal Amplification ◽  
Biomarker Detection ◽  
Sandwich Type ◽  
Rhombic Dodecahedra

Nanozyme-assisted amplification strategies for sandwich-type electrochemical sensor construction.

scholarly journals Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 85
Author(s):  
Anton Popov ◽  
Benediktas Brasiunas ◽  
Asta Kausaite-Minkstimiene ◽  
Almira Ramanaviciene
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Metal Nanoparticle ◽  
Biomarker Detection ◽  
Analytical Instruments ◽  
Electrochemical Immunosensors ◽  
Highly Sensitive ◽  
Recent Developments ◽  
Electrochemical Signal ◽  
Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

Sensitive mutant DNA biomarker detection based on magnetic nanoparticles and nicking endonuclease assisted fluorescence signal amplification

RSC Advances ◽  
2015 ◽  
Vol 5 (26) ◽  
pp. 20020-20024 ◽  
Author(s):  
Na Li ◽  
Zhong Feng Gao ◽  
Bei Hua Kang ◽  
Nian Bing Li ◽  
Hong Qun Luo
Keyword(s):  
Magnetic Nanoparticles ◽  
Signal Amplification ◽  
Fluorescence Signal ◽  
Biomarker Detection ◽  
Background Signal ◽  
Sensitive Mutant ◽  
Nicking Endonuclease ◽  
Low Background ◽  
Target Dna ◽  
Fluorescence Signal Amplification

Amplified fluorescence target DNA detection was developed combining nicking endonuclease assisted target recycling and magnetic nanoparticles with low background signal.

rhEPO/EPO discrimination with ultrasensitive electrochemical biosensor based on sandwich-type nano-Au/ZnO sol–gel/nano-Au signal amplification

2013 ◽  
Vol 50 ◽  
pp. 217-223 ◽  
Author(s):  
Liqun Zhang ◽  
Yunxia Wang ◽  
Jingjing Wang ◽  
Jianfeng Shi ◽  
Kun Deng ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Sol Gel ◽  
Sandwich Type

Synergistic effect of sandwich polyoxometalates and copper–imidazole complexes for enhancing the peroxidase-like activity

RSC Advances ◽  
2015 ◽  
Vol 5 (96) ◽  
pp. 78771-78779 ◽  
Author(s):  
Dong-Feng Chai ◽  
Zhuo Ma ◽  
Hong Yan ◽  
YunFeng Qiu ◽  
Hong Liu ◽  
...  
Keyword(s):  
Synergistic Effect ◽  
Sandwich Polyoxometalates ◽  
Imidazole Complexes ◽  
Sandwich Type

Two inorganic–organic hybrids based on copper(ii)–imidazole complex modified sandwich-type tungstobismuthate or tungstoantimonite, have been synthesized, demonstrating higher peroxidase-like activity using TMB as a peroxidase substrate.

Ultrasensitive detection of NDM-1 resistant bacteria based on signal amplification with sandwich-type LNA electrochemical biochips

2020 ◽  
Vol 306 ◽  
pp. 127556
Author(s):  
Liqun Zhang ◽  
Wenbin Liang ◽  
Qiaosheng Ran ◽  
Fei Liu ◽  
Dong Chen ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Resistant Bacteria ◽  
Ultrasensitive Detection ◽  
Sandwich Type
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