Synergistic effect of sandwich polyoxometalates and copper–imidazole complexes for enhancing the peroxidase-like activity

RSC Advances ◽  
2015 ◽  
Vol 5 (96) ◽  
pp. 78771-78779 ◽  
Author(s):  
Dong-Feng Chai ◽  
Zhuo Ma ◽  
Hong Yan ◽  
YunFeng Qiu ◽  
Hong Liu ◽  
...  
Keyword(s):  
Synergistic Effect ◽  
Sandwich Polyoxometalates ◽  
Imidazole Complexes ◽  
Sandwich Type

Two inorganic–organic hybrids based on copper(ii)–imidazole complex modified sandwich-type tungstobismuthate or tungstoantimonite, have been synthesized, demonstrating higher peroxidase-like activity using TMB as a peroxidase substrate.

Rigid trisporphyrin with 1,3,5-triazine core: Synthesis, spectroscopy, and DABCO-induced self-assembly properties

2020 ◽  
Vol 24 (08) ◽  
pp. 1066-1073
Author(s):  
Chunhua Huang ◽  
Bin Shen ◽  
Kang Wang ◽  
Jing’an Lu ◽  
Xiao’fei Sun
Keyword(s):  
Ir Spectroscopy ◽  
Synergistic Effect ◽  
Self Assembly ◽  
Zinc Complex ◽  
Spectrophotometric Titration ◽  
Spectroscopic Methods ◽  
H Nmr ◽  
Sandwich Type ◽  
Spectrophotometric Titrations ◽  
Application Potential

A rigid Zn–trisporphyrin (1), the Zinc complex of 2,4,6-tris(5,10,15-triphenylporphyrinatozinc)-1,3,5-triazine (2) with three porphyrin moieties bridged by a rigid 1,3,5-triazine group, was synthesized and characterized by a series of spectroscopic methods including mass, 1H NMR, electronic absorption, and IR spectroscopy in addition to elemental analysis. The UV-vis spectrophotometric titration results revealed that along with the addition of the 1,4-diazabicyclo[2.2.2]octane (DABCO) form 0 to 3 equiv, 1 could form a 2:3 sandwich-type coordination cage in chloroform, which then transformed into a 1:3 open complex when the DABCO concentration was more than 3 equiv. Such DABCO-induced self- and disassembly processes were also confirmed by 1H NMR spectrophotometric titrations. In particular, it was demonstrated by comparative studies that the synergistic effect of the three porphyrin moieties linked together by the rigid 1,3,5-triazine group in 1 promoted the formation and stabilization of the 2:3 sandwich-type coordination cage. This result will be helpful towards the fabrication of various self-assembly structures based on metalloporphyrins with application potential in diverse areas such as molecular recognition and separation.

The synergistic effect of Au-COF nanosheets and artificial peroxidase Au@ZIF-8(NiPd) rhombic dodecahedra for signal amplification for biomarker detection

Nanoscale ◽  
2019 ◽  
Vol 11 (42) ◽  
pp. 20221-20227 ◽  
Author(s):  
Tingting Zhang ◽  
Yu Song ◽  
Yue Xing ◽  
Yue Gu ◽  
Xiaoyi Yan ◽  
...  
Keyword(s):  
Synergistic Effect ◽  
Electrochemical Sensor ◽  
Signal Amplification ◽  
Biomarker Detection ◽  
Sandwich Type ◽  
Rhombic Dodecahedra

Nanozyme-assisted amplification strategies for sandwich-type electrochemical sensor construction.

A Monoclonal Antibody-Based Enzyme Immunoassay for Fibrin Degradation Products in Plasma

1988 ◽  
Vol 59 (02) ◽  
pp. 310-315 ◽  
Author(s):  
P W Koppert ◽  
E Hoegee-de Nobel ◽  
W Nieuwenhuizen
Keyword(s):  
Enzyme Immunoassay ◽  
Degradation Products ◽  
Blood Clot ◽  
Tissue Type ◽  
Fibrin Degradation Products ◽  
Type Plasminogen Activator ◽  
Strong Positive Reaction ◽  
Sandwich Type ◽  
Capture Antibody

SummaryWe have developed a sandwich-type enzyme immunoassay (EIA) for the quantitation of fibrin degradation products (FbDP) in plasma with a time-to-result of only 45 minutes.* The assay is based on the combination of the specificities of two monoclonal antibodies (FDP-14 and DD-13), developed in our institute. FDP-14, the capture antibody, binds both fibrinogen degradation products (FbgDP) and FbDP, but does not react with the parent fibrin(ogen) molecules. It has its epitope in the E-domain of the fibrinogen molecule on the Bβ-chain between amino acids 54-118. Antibody DD-13 was raised using D-dimer as antigen and is used as a tagging antibody, conjugated with horse-radish peroxidase. A strong positive reaction is obtained with a whole blood clot lysate (lysis induced by tissue-type plasminogen activator) which is used as a standard. The EIA does virtually not detect FbgDP i. e. purified fragments X, Y, or FbgDP generated in vitro in plasma by streptokinase treatment. This indicates that the assay is specific for fibrin degradation products.We have successfully applied this assay to the plasma of patients with a variety of diseased states. In combination with the assay previously developed by us for FbgDP and for the total amount of FbgDP + FbDP (TDP) in plasma, we are now able to study the composition of TDP in patients plasma in terms of FbgDP and FbDP.

Characteristics Of The Structure Formation Of Gypsum Binder Modified With Zinc Hydrosilicates

2020 ◽  
pp. 40-46
Keyword(s):  
Synergistic Effect ◽  
Physicochemical Properties ◽  
Structure Formation ◽  
Silicic Acid ◽  
Chemical Properties ◽  
Crystal Formation ◽  
Ability To Act ◽  
Chemical Factors ◽  
Sorption Characteristics

The authors' methodic for assessing the role of chemical and physic-chemical factors during the structure formation of gypsum stone is presented in the article. The methodic is also makes it possible to reveal the synergistic effect and to determine the ranges of variation of controls factors that ensure maximum values of such effect. The effect of a micro-sized modifier based on zinc hydro-silicates on the structure formation of building gypsum is analyzed and corresponding dependencies are found. It is shown that effects of influence of modifier on the properties of gypsum compositions are determined by chemical properties of modifier. Among the mentioned properties are sorption characteristics (which depend on the amount of silicic acid and its state) and physicochemical properties - the ability to act as a substrate during crystal formation. The proposed method can also be extended to other binding substances and materials. This article contributes to the understanding of the processes that occur during the structure formation of composites, which will make it possible to control the structure formation in the future, obtaining materials with a given set of properties.

Spectrum of Defect States in Porous Organic Low-k Dielectric Films, Annealed in Argon and Nitrogen

2003 ◽  
Vol 766 ◽  
Author(s):  
V. Ligatchev ◽  
T.K.S. Wong ◽  
T.K. Goh ◽  
Rusli Suzhu Yu
Keyword(s):  
Deep Level ◽  
Dielectric Films ◽  
Silicon Substrates ◽  
Reverse Bias Voltage ◽  
Defect States ◽  
Single Side ◽  
Sandwich Type ◽  
Transient Spectroscopy ◽  
P Type ◽  
Spectrum Deconvolution

AbstractDefect spectrum N(E) of porous organic dielectric (POD) films is studied with capacitance deep-level-transient-spectroscopy (C-DLTS) in the energy range up to 0.7 eV below conduction band bottom Ec. The POD films were prepared by spin coating onto 200mm p-type (1 – 10 Δcm) single-side polished silicon substrates followed by baking at 325°C on a hot plate and curing at 425°C in furnace. The film thickness is in the 5000 – 6000 Å range. The ‘sandwich’ -type NiCr/POD/p-Si/NiCr test structures showed both rectifying DC current-voltage characteristics and linear 1/C2 vs. DC reverse bias voltage. These confirm the applicability of the C-DLTS technique for defect spectrum deconvolution and the n-type conductivity of the studied films. Isochronal annealing (30 min in argon or 60 min in nitrogen) has been performed over the temperature range 300°C - 650°C. The N(E) distribution is only slightly affected by annealing in argon. However, the distribution depends strongly on the annealing temperature in nitrogen ambient. A strong N(E) peak at Ec – E = 0.55 – 0.60 eV is detected in all samples annealed in argon but this peak is practically absent in samples annealed in nitrogen at Ta < 480°C. On the other hand, two new peaks at Ec – E = 0.12 and 0.20 eV appear in the N(E) spectrum of the samples annealed in nitrogen at Ta = 650°C. The different features of the defect spectrum are attributed to different interactions of argon and nitrogen with dangling carbon bonds on the intra-pore surfaces.

The Synergistic Effect of Suplatast Tosilate and Tacrolimus Hydrate Ointment on Adult Atopic Dermatitis with Intractable Face Erythema

2005 ◽  
Vol 67 (3) ◽  
pp. 247-251 ◽  
Author(s):  
Motoi TAKENAKA ◽  
Sang Jae BAE ◽  
Shinichi SATO ◽  
Ichiro KATAYAMA
Keyword(s):  
Atopic Dermatitis ◽  
Synergistic Effect
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