Multifunctional inhibitors of β-amyloid aggregation based on MoS2/AuNR nanocomposites with high near-infrared absorption

Nanoscale ◽  
2019 ◽  
Vol 11 (18) ◽  
pp. 9185-9193 ◽  
Author(s):  
Xinhuan Wang ◽  
Qiusen Han ◽  
Xueliang Liu ◽  
Chen Wang ◽  
Rong Yang
Keyword(s):  
Infrared Absorption ◽  
Near Infrared ◽  
Cell Toxicity ◽  
Amyloid Aggregation ◽  
Β Amyloid

MoS2/AuNR nanocomposites are constructed for the modulation of β-amyloid aggregation, photothermal destabilization of mature fibrils and reduction of their cell-toxicity.

A theranostic agent for in vivo near-infrared imaging of β-amyloid species and inhibition of β-amyloid aggregation

Biomaterials ◽  
2016 ◽  
Vol 94 ◽  
pp. 84-92 ◽  
Author(s):  
Yinhui Li ◽  
Di Xu ◽  
See-Lok Ho ◽  
Hung-Wing Li ◽  
Ronghua Yang ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Imaging ◽  
Amyloid Aggregation ◽  
Near Infrared Imaging ◽  
Theranostic Agent ◽  
Β Amyloid

Аnticholinesterase and antioxidant activity of new binary conjugates of (с)-carbolines

2019 ◽  
Vol 484 (1) ◽  
pp. 104-108
Author(s):  
G. F. Makhaeva ◽  
E. F. Shevtsova ◽  
N. P. Boltneva ◽  
N. V. Kovaleva ◽  
E. V. Rudakova ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Antioxidant Activity ◽  
Anticholinesterase Activity ◽  
Amyloid Aggregation ◽  
Varying Length ◽  
Β Amyloid ◽  
New Compounds

This study presents the synthesis of binary tetrohydro-γ-carbolines with ditriazol spacers of varying length, which exhibit anticholinesterase and antioxidant activity, as compared to the original Dimebon prototype. Anticholinesterase activity suggests the potential ability of the new compounds to block β-amyloid aggregation induced by anticholinesterase, making them promising candidates for further research preparations for the treatment of Alzheimer's disease. Particular attention should be paid to the conjugate with an intertriazol hexamethylene spacer, which can be regarded as the leading compound in this series.

Study on the Near-infrared Absorption Properties of ZnGeP2 Single Crystals

2010 ◽  
Vol 25 (10) ◽  
pp. 1029-1033
Author(s):  
Shi-Xing XIA ◽  
Chun-Hui YANG ◽  
Chong-Qiang ZHU ◽  
Tian-Hui MA ◽  
Meng WANG ◽  
...  
Keyword(s):  
Single Crystals ◽  
Infrared Absorption ◽  
Near Infrared ◽  
Absorption Properties

N,O-Benzamide difluoroboron complexes as near-infrared probes for the detection of β-amyloid and tau fibrils

2020 ◽  
Vol 56 (53) ◽  
pp. 7269-7272
Author(s):  
Yimin Chen ◽  
Chang Yuan ◽  
Tianxin Xie ◽  
Yuying Li ◽  
Bin Dai ◽  
...  
Keyword(s):  
Near Infrared ◽  
Β Amyloid ◽  
Infrared Probes ◽  
Tau Fibrils

In this study, a series of organo difluoroboron probes with a BF2 benzamide moiety was designed, prepared and evaluated as Aβ and Tau probes.

Pyrrole-bridged quinones: π-electronic systems that modulate electronic structures by tautomerism and deprotonation

2021 ◽  
Author(s):  
Shinya Sugiura ◽  
Hiromitsu Maeda
Keyword(s):  
Infrared Absorption ◽  
Electronic Structures ◽  
Near Infrared ◽  
Ion Pairing ◽  
Anion Binding ◽  
Electronic Systems

A new series of π-extended quinone derivatives containing a pyrrole bridge exhibited NH/OH-type tautomerization and anion binding along with deprotonation that induced near-infrared absorption and ion-pairing assemblies.

scholarly journals Characterization and mapping of hematite ore mineral classes using hyperspectral remote sensing technique: a case study from Bailadila iron ore mining region

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Ibrahim Shaik ◽  
S. K. Begum ◽  
P. V. Nagamani ◽  
Narayan Kayet
Keyword(s):  
Infrared Absorption ◽  
Near Infrared ◽  
Spectral Feature ◽  
Absorption Feature ◽  
X Ray ◽  
Remote Sensing Technique ◽  
Ore Minerals ◽  
Feature Fitting ◽  
Hematite Ore

AbstractThe study demonstrates a methodology for mapping various hematite ore classes based on their reflectance and absorption spectra, using Hyperion satellite imagery. Substantial validation is carried out, using the spectral feature fitting technique, with the field spectra measured over the Bailadila hill range in Chhattisgarh State in India. The results of the study showed a good correlation between the concentration of iron oxide with the depth of the near-infrared absorption feature (R2 = 0.843) and the width of the near-infrared absorption feature (R2 = 0.812) through different empirical models, with a root-mean-square error (RMSE) between < 0.317 and < 0.409. The overall accuracy of the study is 88.2% with a Kappa coefficient value of 0.81. Geochemical analysis and X-ray fluorescence (XRF) of field ore samples are performed to ensure different classes of hematite ore minerals. Results showed a high content of Fe > 60 wt% in most of the hematite ore samples, except banded hematite quartzite (BHQ) (< 47 wt%).

Sign in / Sign up

Export Citation Format

Share Document