Paper-based selective and quantitative detection of uric acid using citrate-capped Pt nanoparticles (PtNPs) as a colorimetric sensing probe through a simple and remote-based device

2019 ◽  
Vol 43 (20) ◽  
pp. 7636-7645 ◽  
Author(s):  
Muhsin Ali ◽  
Muhammad Asad Ullah Khalid ◽  
Imran Shah ◽  
Soo Wan Kim ◽  
Young Su Kim ◽  
...  
Keyword(s):  
Uric Acid ◽  
Point Of Care ◽  
Pt Nanoparticles ◽  
Quantitative Detection ◽  
Point Of Care Testing ◽  
Colorimetric Sensing

A colorimetric portable setup was developed for remote UA measurements using a smartphone-based application to demonstrate its use in point-of-care testing.

Point-of-care testing of melamine via gas pressure readout using polythymine-coated Au@Pt nanoparticles through specific triple hydrogen-bonding recognition

The Analyst ◽  
2021 ◽  
Author(s):  
Ling Li ◽  
Hanwen Deng ◽  
Zhongshuai Zhao ◽  
Zhongde Liu
Keyword(s):  
Hydrogen Bonding ◽  
Point Of Care ◽  
Pt Nanoparticles ◽  
Gas Pressure ◽  
Point Of Care Testing ◽  
Highly Sensitive

On the basis of the target-responsive aggregation occurrence of Au@PtNPs, a pressure-based signaling strategy was developed for highly sensitive and specific melamine detection not only in laboratory but also in point-of-care (POC) settings.

scholarly journals Acoustofluidic Micromixing Enabled Hybrid Integrated Colorimetric Sensing, for Rapid Point-of-Care Measurement of Salivary Potassium

Biosensors ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 73 ◽  
Author(s):  
Vikram Surendran ◽  
Thomas Chiulli ◽  
Swetha Manoharan ◽  
Stephen Knisley ◽  
Muthukumaran Packirisamy ◽  
...  
Keyword(s):  
Color Change ◽  
Point Of Care ◽  
Sample Volume ◽  
Point Of Care Testing ◽  
Colorimetric Sensing ◽  
In Situ Tests ◽  
Detection Scheme ◽  
Chip Technology ◽  
Whole Saliva ◽  
Microfluidic Biosensor

The integration of microfluidics with advanced biosensor technologies offers tremendous advantages such as smaller sample volume requirement and precise handling of samples and reagents, for developing affordable point-of-care testing methodologies that could be used in hospitals for monitoring patients. However, the success and popularity of point-of-care diagnosis lies with the generation of instantaneous and reliable results through in situ tests conducted in a painless, non-invasive manner. This work presents the development of a simple, hybrid integrated optical microfluidic biosensor for rapid detection of analytes in test samples. The proposed biosensor works on the principle of colorimetric optical absorption, wherein samples mixed with suitable chromogenic substrates induce a color change dependent upon the analyte concentration that could then be detected by the absorbance of light in its path length. This optical detection scheme has been hybrid integrated with an acoustofluidic micromixing unit to enable uniform mixing of fluids within the device. As a proof-of-concept, we have demonstrated the real-time application of our biosensor format for the detection of potassium in whole saliva samples. The results show that our lab-on-a-chip technology could provide a useful strategy in biomedical diagnoses for rapid analyte detection towards clinical point-of-care testing applications.

Point-of-care testing (POCT) of patients with a high concentration of uric acid by using alginate hydrogel microspheres embedded with CdZnTeS QDs and urate oxidase (Alg@QDs-UOx MSs)

The Analyst ◽  
2021 ◽  
Author(s):  
Fan Lu ◽  
Yeling Yang ◽  
Yucheng Liu ◽  
Fubing Wang ◽  
Xinghu Ji ◽  
...  
Keyword(s):  
Uric Acid ◽  
Convenient Method ◽  
Point Of Care ◽  
Urate Oxidase ◽  
Point Of Care Testing ◽  
High Concentration ◽  
Alginate Hydrogel ◽  
Hydrogel Microspheres

A more convenient method for POCT of patients with a high concentration of uric acid by using Alg@QDs-UOx MSs is developed.

scholarly journals Polystyrene Microsphere-Based Immunochromatographic Assay for Detection of Aflatoxin B1 in Maize

Biosensors ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 200
Author(s):  
Jin Wang ◽  
Xiangmei Li ◽  
Xing Shen ◽  
Ang Zhang ◽  
Jinxiu Liu ◽  
...  
Keyword(s):  
Aflatoxin B1 ◽  
Limit Of Detection ◽  
Point Of Care ◽  
Immunochromatographic Assay ◽  
Quantitative Detection ◽  
Point Of Care Testing ◽  
Polystyrene Microsphere ◽  
Accuracy And Precision ◽  
Wide Range ◽  
Liquid Chromatography Tandem Mass

Aflatoxin B1 (AFB1), a mycotoxin, is hepatotoxic, carcinogenic, and nephrotoxic in humans and animals, and contaminate a wide range of maize. In this study, an immunochromatographic assay (ICA) based on polystyrene microspheres (PMs) was developed for sensitive and quantitative detection of AFB1 in maize. The amounts of PMs, the condition for activating carboxyl groups of PMs, the amount of monoclonal antibody (mAb), and the volume of the immune probe were optimized to enhance the performance PMs-ICA for point-of-care testing of AFB1 in maize. The PMs-ICA showed the cut-off value of 1 ng/mL in phosphate buffer (PB) and 6 µg/kg in maize samples, respectively. The quantitative limit of detection (qLOD) was 0.27 and 1.43 µg/kg in PB and maize samples, respectively. The accuracy and precision of the PMs-ICA were evaluated by analysis of spiked maize samples with recoveries of 96.0% to 107.6% with coefficients of variation below 10%. In addition, the reliability of PMs-ICA was confirmed by the liquid chromatography-tandem mass spectrometry method. The results indicated that the PMs-ICA could be used as a sensitive, simple, rapid point-of-care testing of AFB1 in maize.

Immunosensor for the ultrasensitive and quantitative detection of bladder cancer in point of care testing

2016 ◽  
Vol 84 ◽  
pp. 126-132 ◽  
Author(s):  
Cheng-Hsin Chuang ◽  
Yi-Chun Du ◽  
Ting-Feng Wu ◽  
Cheng-Ho Chen ◽  
Da-Huei Lee ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Point Of Care ◽  
Quantitative Detection ◽  
Point Of Care Testing

A Miniaturized Giant Magnetic Resistance System for Quantitative Detection of Methamphetamine

The Analyst ◽  
2021 ◽  
Author(s):  
Jinhong Guo ◽  
Guopan Yang ◽  
Kunxue Cheng ◽  
Zhengkang Chu ◽  
Yusheng Fu ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Point Of Care ◽  
Lateral Flow ◽  
Quantitative Detection ◽  
Point Of Care Testing ◽  
Resistance System ◽  
Magnetic Resistance

Point-of-care testing (POCT) systems have been greatly developed in recent years. Among them, lateral flow immunochromatography (LFIA) based on magnetic nanoparticles (MNPs) is widely used in various fields due to...

Photoacoustic-Based Miniature Device with Smartphone Readout for Point-of-Care Testing of Uric Acid

2020 ◽  
Vol 92 (24) ◽  
pp. 15699-15704
Author(s):  
Ya-Jie Zhang ◽  
Lan Guo ◽  
Yong-Liang Yu ◽  
Jian-Hua Wang
Keyword(s):  
Uric Acid ◽  
Point Of Care ◽  
Point Of Care Testing ◽  
Miniature Device
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