A Miniaturized Giant Magnetic Resistance System for Quantitative Detection of Methamphetamine

The Analyst ◽  
2021 ◽  
Author(s):  
Jinhong Guo ◽  
Guopan Yang ◽  
Kunxue Cheng ◽  
Zhengkang Chu ◽  
Yusheng Fu ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Point Of Care ◽  
Lateral Flow ◽  
Quantitative Detection ◽  
Point Of Care Testing ◽  
Resistance System ◽  
Magnetic Resistance

Point-of-care testing (POCT) systems have been greatly developed in recent years. Among them, lateral flow immunochromatography (LFIA) based on magnetic nanoparticles (MNPs) is widely used in various fields due to...

A Self-Contained Chemiluminescent Lateral Flow Assay for Point-of-Care Testing

2018 ◽  
Vol 90 (15) ◽  
pp. 9132-9137 ◽  
Author(s):  
Jinqi Deng ◽  
Mingzhu Yang ◽  
Jing Wu ◽  
Wei Zhang ◽  
Xingyu Jiang
Keyword(s):  
Point Of Care ◽  
Lateral Flow ◽  
Lateral Flow Assay ◽  
Point Of Care Testing

Paper-based selective and quantitative detection of uric acid using citrate-capped Pt nanoparticles (PtNPs) as a colorimetric sensing probe through a simple and remote-based device

2019 ◽  
Vol 43 (20) ◽  
pp. 7636-7645 ◽  
Author(s):  
Muhsin Ali ◽  
Muhammad Asad Ullah Khalid ◽  
Imran Shah ◽  
Soo Wan Kim ◽  
Young Su Kim ◽  
...  
Keyword(s):  
Uric Acid ◽  
Point Of Care ◽  
Pt Nanoparticles ◽  
Quantitative Detection ◽  
Point Of Care Testing ◽  
Colorimetric Sensing

A colorimetric portable setup was developed for remote UA measurements using a smartphone-based application to demonstrate its use in point-of-care testing.

scholarly journals Switching from Multiplex to Multimodal Colorimetric Lateral Flow Immunosensor

Sensors ◽  
2020 ◽  
Vol 20 (22) ◽  
pp. 6609
Author(s):  
Simone Cavalera ◽  
Fabio Di Nardo ◽  
Luca Forte ◽  
Francesca Marinoni ◽  
Matteo Chiarello ◽  
...  
Keyword(s):  
Point Of Care ◽  
Lateral Flow ◽  
Proof Of Concept ◽  
Point Of Care Testing ◽  
Human Immunoglobulins ◽  
Immunodeficiency Virus ◽  
Specific Antigens ◽  
Increasing Demand ◽  
Gold Nanomaterials ◽  
Two Parameter

Multiplex lateral flow immunoassay (LFIA) is largely used for point-of-care testing to detect different pathogens or biomarkers in a single device. The increasing demand for multitargeting diagnostics requires multi-informative single tests. In this study, we demonstrated three strategies to upgrade standard multiplex LFIA to multimodal capacity. As a proof-of-concept, we applied the strategies to the differential diagnosis of Human Immunodeficiency Virus (HIV) infection, a widespread pathogen, for which conventional multiplex LFIA testing is well-established. In the new two-parameter LFIA (x2LFIA), we exploited color encoding, in which the binding of multiple targets occurs in one reactive band and the color of the probe reveals which one is present in the sample. By combining the sequential alignment of several reactive zones along the membrane of the LFIA strip and gold nanoparticles and gold nanostars for the differential visualization, in this demonstration, the x2LFIA can furnish information on HIV serotype and stage of infection in a single device. Three immunosensors were designed. The use of bioreagents as the capturing ligand anchored onto the membrane or as the detection ligand labelled with gold nanomaterials affected the performance of the x2LFIA. Higher detectability was achieved by the format involving the HIV-specific antigens as capturing agent and labelled secondary bioligands (anti-human immunoglobulins M and protein G) as the probes.

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