Robust chemical bonding of PMMA microfluidic devices to porous PETE membranes for reliable cytotoxicity testing of drugs

Lab on a Chip ◽  
2019 ◽  
Vol 19 (21) ◽  
pp. 3706-3713 ◽  
Author(s):  
Thao Nguyen ◽  
Su Hyun Jung ◽  
Min Seok Lee ◽  
Tae-Eun Park ◽  
Suk-kyun Ahn ◽  
...  

A GLYMO-based method enables robust fabrication of PMMA–PETE cell-culturing microfluidic devices, which permits more precise cytotoxicity response to lipophilic drugs.

The Analyst ◽  
2020 ◽  
Vol 145 (12) ◽  
pp. 4096-4110 ◽  
Author(s):  
Rajamanickam Sivakumar ◽  
Nae Yoon Lee

This review discusses on various bonding techniques for fabricating microdevices with a special emphasis on the modification of surface assisted by the use of chemicals to assemble microfluidic devices at room temperature under atmospheric pressure.


Author(s):  
M. L. Knotek

Modern surface analysis is based largely upon the use of ionizing radiation to probe the electronic and atomic structure of the surfaces physical and chemical makeup. In many of these studies the ionizing radiation used as the primary probe is found to induce changes in the structure and makeup of the surface, especially when electrons are employed. A number of techniques employ the phenomenon of radiation induced desorption as a means of probing the nature of the surface bond. These include Electron- and Photon-Stimulated Desorption (ESD and PSD) which measure desorbed ionic and neutral species as they leave the surface after the surface has been excited by some incident ionizing particle. There has recently been a great deal of activity in determining the relationship between the nature of chemical bonding and its susceptibility to radiation damage.


Author(s):  
Lilla Krokker ◽  
Borbála Szabó ◽  
Kinga Németh ◽  
Balázs Sarkadi ◽  
Katalin Mészáros ◽  
...  

2016 ◽  
Vol 136 (6) ◽  
pp. 244-249
Author(s):  
Takahiro Watanabe ◽  
Fumihiro Sassa ◽  
Yoshitaka Yoshizumi ◽  
Hiroaki Suzuki

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