Integration of a peptide–DNA conjugate with multiple cyclic signal amplification for the ultrasensitive detection of cathepsin B activity

2020 ◽  
Vol 56 (14) ◽  
pp. 2119-2122 ◽  
Author(s):  
Zi-yue Wang ◽  
Cheng-peng Zhang ◽  
Chun-yang Zhang

We integrate a peptide–DNA conjugate with multiple cyclic signal amplification for the sensitive detection of cathepsin B activity.

2019 ◽  
Vol 55 (48) ◽  
pp. 6827-6830 ◽  
Author(s):  
Yan Zhang ◽  
Xin-yan Wang ◽  
Xianwei Su ◽  
Chun-yang Zhang

We develop a new method for sensitive detection of long noncoding RNAs using duplex-specific nuclease-actuated cyclic enzymatic repairing-mediated signal amplification.


2018 ◽  
Vol 54 (97) ◽  
pp. 13678-13681 ◽  
Author(s):  
Dandan Zhang ◽  
Fei Ma ◽  
Junhong Leng ◽  
Chun-yang Zhang

We develop a new dual-signal amplification-assisted DNAzyme biosensor for sensitive detection of Argonaute 2 (Ago2) activity.


2021 ◽  
Author(s):  
Mengda Cao ◽  
Yongxin Liu ◽  
Chen Lu ◽  
Miao Guo ◽  
Lin Li ◽  
...  

The accurate detection of allergen specific IgE (sIgE) is fundamental in the diagnosis of allergic disease. The present commercial platforms fail to meet the need for personalized diagnosis, due to...


RSC Advances ◽  
2015 ◽  
Vol 5 (64) ◽  
pp. 51990-51999 ◽  
Author(s):  
Fei Liu ◽  
Guiming Xiang ◽  
Liqun Zhang ◽  
Dongneng Jiang ◽  
Linlin Liu ◽  
...  

lncRNA biosensor based on single-wall carbon nanotubes wrapped with Au–Rh hollow nanospheres (Au/Rh-HNP@SWCNT) complex signal amplification and an l-Cys Au nano-film provided ultrasensitive detection for the nuclear paraspeckle assembly transcript 1 (NEAT1).


2015 ◽  
Vol 51 (90) ◽  
pp. 16271-16274 ◽  
Author(s):  
Jing Zheng ◽  
Dandan Ma ◽  
Muling Shi ◽  
Junhui Bai ◽  
Yinhui Li ◽  
...  

In this communication, we proposed a new enzyme-free quadratic SERS signal amplification approach for the ultrasensitive detection of circulating miRNA in human serum.


RSC Advances ◽  
2015 ◽  
Vol 5 (36) ◽  
pp. 28324-28331 ◽  
Author(s):  
Chaomin Gao ◽  
Min Su ◽  
Yanhu Wang ◽  
Shenguang Ge ◽  
Jinghua Yu

Ultrasensitive detection of CEA based on Ag nanospheres modified paper working electrode platform and Ru(bpy)32+@Au nanocages signal amplification.


The Analyst ◽  
2021 ◽  
Author(s):  
Chuyan Zhang ◽  
Zewei Luo ◽  
Mengfan Wu ◽  
Wei Ning ◽  
Ziyi Tian ◽  
...  

Sensitive and efficient monitoring of food-borne bacteria is of great importance for food safety control. Herein, a novel biosensor for highly sensitive detection of Staphylococcus aureus (S. aureus) was constructed...


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