A self-powered 3D DNA walker with programmability and signal-amplification for illuminating microRNA in living cells

2020 ◽  
Vol 56 (14) ◽  
pp. 2135-2138 ◽  
Author(s):  
Xue-Jiao Yang ◽  
Mei-Rong Cui ◽  
Xiang-Ling Li ◽  
Hong-Yuan Chen ◽  
Jing-Juan Xu

We construct a target-triggered, self-powered 3D DNA walker for achieving intracellular signal amplification and sensitive imaging analysis of microRNAs.

2019 ◽  
Vol 55 (89) ◽  
pp. 13366-13369 ◽  
Author(s):  
Mei-Rong Cui ◽  
Xiang-Ling Li ◽  
Jing-Juan Xu ◽  
Hong-Yuan Chen

We constructed a versatile self-powered DNAzyme–MnO2 nanosystem for intracellular signal amplification and sensitive imaging of miRNAs in living cells.


Nanoscale ◽  
2021 ◽  
Author(s):  
Fu-Ting Wang ◽  
Ke-Jing Huang ◽  
Yangyang Hou ◽  
Xuecai Tan ◽  
Xu Wu ◽  
...  

A self-powered microRNAs biosensor with triple signal amplification systems is assembled through integration of three-dimensional DNA walker, enzymatic biofuel cells and capacitor. The DNA walker is designed from an enzyme-free...


The Analyst ◽  
2021 ◽  
Author(s):  
Na Wang ◽  
Yong Jian Jiang ◽  
Xu Zhang ◽  
Hua Rong Lin ◽  
Feng Cheng ◽  
...  

An Exo III-propelled stochastic 3D DNA walker based on nanosurface energy transfer was developed for enzyme-assisted DNA detection with signal amplification.


2020 ◽  
Vol 8 (7) ◽  
pp. 1389-1395 ◽  
Author(s):  
Fu-Ting Wang ◽  
Yi-Han Wang ◽  
Jing Xu ◽  
Ke-Jing Huang

A high-energy self-powered sensing platform for the ultrasensitive detection of proteins is developed based on enzymatic biofuel cells (EBFCs) by using DNA bioconjugate assisted signal amplification.


2020 ◽  
Vol 59 (47) ◽  
pp. 20582-20590
Author(s):  
Liman Xian ◽  
Haoying Ge ◽  
Ning Xu ◽  
Feng Xu ◽  
Qichao Yao ◽  
...  

2018 ◽  
Vol 9 (5) ◽  
pp. 1184-1190 ◽  
Author(s):  
Xiangdan Meng ◽  
Wenhao Dai ◽  
Kai Zhang ◽  
Haifeng Dong ◽  
Xueji Zhang

Herein, we design a smart autonomous ATP self-powered strand displacement cascade amplification (SDCA) system for highly sensitive multiple intracellular miRNA detection.


2004 ◽  
Vol 101 (19) ◽  
pp. 7317-7322 ◽  
Author(s):  
H. Murakoshi ◽  
R. Iino ◽  
T. Kobayashi ◽  
T. Fujiwara ◽  
C. Ohshima ◽  
...  

2005 ◽  
Vol 320 (3) ◽  
pp. 447-453 ◽  
Author(s):  
Masayuki Tanaka ◽  
Mayumi Nishi ◽  
Masafumi Morimoto ◽  
Tohru Sugimoto ◽  
Mitsuhiro Kawata

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