Hydrophobicity and CH/π-interaction-driven self-assembly of amphiphilic aromatic hydrocarbons into nanosheets

2019 ◽  
Vol 55 (99) ◽  
pp. 14950-14953 ◽  
Author(s):  
Tsuyoshi Nishikawa ◽  
Hiroki Narita ◽  
Soichiro Ogi ◽  
Yoshikatsu Sato ◽  
Shigehiro Yamaguchi
Keyword(s):  
Aqueous Solution ◽  
Aromatic Hydrocarbons ◽  
Self Assembly ◽  
Molecular Packing ◽  
Packing Structure ◽  
Dilute Aqueous Solution ◽  
Micrometer Scale

The hydrophobicity and CH/π-interaction-driven self-assembly of an amphiphile that contains a biphenylanthracene group furnishes micrometer-scale nanosheets with a windmill-shaped molecular packing structure in dilute aqueous solution.

scholarly journals Self-assembly of liquid crystal block copolymer PEG-b-smectic polymer in pure state and in dilute aqueous solution

2009 ◽  
Vol 143 ◽  
pp. 235 ◽  
Author(s):  
Bing Xu ◽  
Rafael Piñol ◽  
Merveille Nono-Djamen ◽  
Sandrine Pensec ◽  
Patrick Keller ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Liquid Crystal ◽  
Block Copolymer ◽  
Self Assembly ◽  
Pure State ◽  
Dilute Aqueous Solution ◽  
Crystal Block

scholarly journals Nanostructures by self-assembly of polyglycidol-derivatized lipids

RSC Advances ◽  
2014 ◽  
Vol 4 (70) ◽  
pp. 37208-37219 ◽  
Author(s):  
Pavel Bakardzhiev ◽  
Stanislav Rangelov ◽  
Barbara Trzebicka ◽  
Denitsa Momekova ◽  
Georgi Lalev ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Self Assembly ◽  
Lamellar Structures ◽  
Dilute Aqueous Solution ◽  
Spherical Micelles

Polyglycidol-derivatized lipids were successfully prepared and their self-assembly in dilute aqueous solution into spherical micelles and lamellar structures was investigated.

Self-Assembly of Thermosensitive Amphiphilic Pentablock Terpolymer PNIPAMx-b-PtBA90-b-PPO36-b-PtBA90-b-PNIPAMx in Dilute Aqueous Solution

2018 ◽  
Vol 51 (24) ◽  
pp. 10136-10149 ◽  
Author(s):  
Chao Lv ◽  
Zhijun Zhang ◽  
Jia Gao ◽  
Jinqiao Xue ◽  
Jianyuan Li ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Self Assembly ◽  
Dilute Aqueous Solution

Structural characterization of the model amphipathic peptide Ac-LKKLLKLLKKLLKL-NH2 in aqueous solution and with 2,2,2-trifluoroethanol and 1,1,1,3,3,3-hexafluoroisopropanol

2013 ◽  
Vol 91 (6) ◽  
pp. 406-413 ◽  
Author(s):  
Garry W. Buchko ◽  
Avijita Jain ◽  
Matthew L. Reback ◽  
Wendy J. Shaw
Keyword(s):  
Aqueous Solution ◽  
Self Assembly ◽  
Helical Structure ◽  
Cd Spectroscopy ◽  
Size Exclusion ◽  
Amphipathic Peptide ◽  
Amphipathic Peptides ◽  
Fluorinated Alcohols ◽  
Dilute Aqueous Solution

Short-chain amphipathic peptides are promising components in the new generation of engineered biomaterials. The model 14-residue leucine–lysine peptide Ac-LKKLLKLLKKLLKL-NH2 (LKα) is one such amphipathic peptide. In dilute aqueous solution (<0.05 mmol/L), it was previously proposed, using CD spectroscopic data, that LKα existed in a cooperative monomeric (unstructured) – tetrameric (α-helical) equilibrium that shifted towards the tetramer at high NaCl and peptide concentrations. Here, at similar peptide concentrations, CD spectroscopy shows that LKα readily adopts α-helical structure in the presence of 2,2,2-trifluoroethanol (TFE) and 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) with maximal helical character in 20% TFE and ∼10% HFIP (v/v). The helical character in fluorinated alcohols suggested by the CD data at low peptide concentrations (0.06 mmol/L) is corroborated at high peptide concentrations (1.5 mmol/L) by NMR NOE data that also show that 1.5 mmol/L LKα is helical in 100% water. Size exclusion chromatography and estimations of rotational correlation times (τc) showed that the self-assembled LKα complexes contained three to five peptides. Removing the N-terminal acetyl group prevents LKα from forming helices and self-associating at high NaCl and peptide concentrations. This more detailed characterization of the structural and physical properties of LKα over a greater range of peptide concentrations and in the presence of fluorinated alcohols will assist the design of biomaterials containing amphipathic peptides and guide the ability to control self-assembly.

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