In situ self-assembly of conjugated polyelectrolytes for cancer targeted imaging and photodynamic therapy

2020 ◽  
Vol 8 (8) ◽  
pp. 2156-2163 ◽  
Author(s):  
Syeda Sadia Khatoon ◽  
Yanyan Chen ◽  
Hao Zhao ◽  
Fengting Lv ◽  
Libing Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Self Assembly ◽  
Targeted Imaging ◽  
Conjugated Polyelectrolytes ◽  
Targeted Killing

Both the specific aggregation of PFT-SH in cancer cells and its ROS producing ability led to its use in the targeted killing of cancer cells through efficient photodynamic therapy.

In-Situ Electrostatic Self-Assembly of Conjugated Polyelectrolytes in a Film

2014 ◽  
Vol 1 (9) ◽  
pp. 1400360 ◽  
Author(s):  
Wang-Eun Lee ◽  
Young-Jae Jin ◽  
Beomsu Shin-Il Kim ◽  
Giseop Kwak ◽  
Toshikazu Sakaguchi ◽  
...  
Keyword(s):  
Self Assembly ◽  
Conjugated Polyelectrolytes

Supramolecular assembly of fluorogenic glyco-dots from perylenediimide-based glycoclusters for targeted imaging of cancer cells

2017 ◽  
Vol 53 (87) ◽  
pp. 11937-11940 ◽  
Author(s):  
Ying Liu ◽  
Ding-Kun Ji ◽  
Lei Dong ◽  
Nicolas Galanos ◽  
Yi Zang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Triple Negative Breast Cancer ◽  
Self Assembly ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
Supramolecular Assembly ◽  
Targeted Imaging

Supramolecular self-assembly between perylenediimide-based glycoclusters and a red-emitting fluorophore produces structurally uniform and stable glyco-dots amenable to targeted fluorogenic imaging of liver and triple-negative breast cancer cells.

scholarly journals A self-reporting AIE probe with a built-in singlet oxygen sensor for targeted photodynamic ablation of cancer cells

2016 ◽  
Vol 7 (3) ◽  
pp. 1862-1866 ◽  
Author(s):  
Youyong Yuan ◽  
Chong-Jing Zhang ◽  
Shidang Xu ◽  
Bin Liu
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Cancer Cells ◽  
Oxygen Sensor ◽  
Aggregation Induced Emission ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation

A probe for the in situ monitoring of singlet oxygen generation during targeted theranostic photodynamic therapy is developed based on a photosensitizer with aggregation-induced emission (AIE) characteristics and conjugated to a fluorogenic rhodol dye via a singlet oxygen cleavable linker.

scholarly journals In situ recognition of cell-surface glycans and targeted imaging of cancer cells

2013 ◽  
Vol 3 (1) ◽  
Author(s):  
Xiao-Ding Xu ◽  
Han Cheng ◽  
Wei-Hai Chen ◽  
Si-Xue Cheng ◽  
Ren-Xi Zhuo ◽  
...  
Keyword(s):  
Cell Surface ◽  
Cancer Cells ◽  
Targeted Imaging ◽  
Cell Surface Glycans

A single-chromophore-based agent enables rapid sensing of intracellular hypochlorous acid and in-situ photodynamic therapy to cancer cells

2019 ◽  
Vol 1061 ◽  
pp. 142-151 ◽  
Author(s):  
Kaiquan Zhang ◽  
Yanlin Lv ◽  
Jiaqi Meng ◽  
Jie Wang ◽  
Aidong Peng ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Hypochlorous Acid

scholarly journals Supramolecular core–glycoshell polythiophene nanodots for targeted imaging and photodynamic therapy

2017 ◽  
Vol 53 (70) ◽  
pp. 9793-9796 ◽  
Author(s):  
Hai-Hao Han ◽  
Chang-Zheng Wang ◽  
Yi Zang ◽  
Jia Li ◽  
Tony D. James ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Triple Negative Breast Cancer ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
Targeted Imaging

We show that supramolecular core–glycoshell nanodots are capable of targeted imaging and photodynamic therapy of liver and triple-negative breast cancer cells.

Amphiphilic copolymer coated upconversion nanoparticles for near-infrared light-triggered dual anticancer treatment

Nanoscale ◽  
2014 ◽  
Vol 6 (24) ◽  
pp. 14903-14910 ◽  
Author(s):  
Shun Yang ◽  
Najun Li ◽  
Zhuang Liu ◽  
Wenwei Sha ◽  
Dongyun Chen ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Controlled Release ◽  
Cancer Cells ◽  
Self Assembly ◽  
Near Infrared ◽  
Amphiphilic Copolymer ◽  
Infrared Light ◽  
Upconversion Nanoparticles ◽  
Assembly Process ◽  
Anticancer Treatment

The light-triggered controlled release of anticancer drugs accompanied with NIR-responsive photodynamic therapy was performed via a self-assembly process. Under 980 nm laser, the cancer cells could be effectively inhibited by released drugs and singlet oxygen simultaneously.

scholarly journals Selectively enhancing radiosensitivity of cancer cells via in situ enzyme-instructed peptide self-assembly

2020 ◽  
Vol 10 (12) ◽  
pp. 2374-2383
Author(s):  
Yang Gao ◽  
Jie Gao ◽  
Ganen Mu ◽  
Yumin Zhang ◽  
Fan Huang ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Self Assembly

In vitro and in vivo polysaccharides assembly: ultrastructural and cytochemical study of growing plant cell wall components.

1978 ◽  
Vol 36 (2) ◽  
pp. 434-435
Author(s):  
D. Reis ◽  
B. Vian ◽  
J. C. Roland
Keyword(s):  
Cell Wall ◽  
Self Assembly ◽  
Plant Cell Wall ◽  
Higher Plants ◽  
Three Dimensional ◽  
Cytochemical Study ◽  
Wall Components

Wall morphogenesis in higher plants is a problem still open to controversy. Until now the possibility of a transmembrane control and the involvement of microtubules were mostly envisaged. Self-assembly processes have been observed in the case of walls of Chlamydomonas and bacteria. Spontaneous gelling interactions between xanthan and galactomannan from Ceratonia have been analyzed very recently. The present work provides indications that some processes of spontaneous aggregation could occur in higher plants during the formation and expansion of cell wall.Observations were performed on hypocotyl of mung bean (Phaseolus aureus) for which growth characteristics and wall composition have been previously defined.In situ, the walls of actively growing cells (primary walls) show an ordered three-dimensional organization (fig. 1). The wall is typically polylamellate with multifibrillar layers alternately transverse and longitudinal. Between these layers intermediate strata exist in which the orientation of microfibrils progressively rotates. Thus a progressive change in the morphogenetic activity occurs.

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