scholarly journals A self-reporting AIE probe with a built-in singlet oxygen sensor for targeted photodynamic ablation of cancer cells

2016 ◽  
Vol 7 (3) ◽  
pp. 1862-1866 ◽  
Author(s):  
Youyong Yuan ◽  
Chong-Jing Zhang ◽  
Shidang Xu ◽  
Bin Liu

A probe for the in situ monitoring of singlet oxygen generation during targeted theranostic photodynamic therapy is developed based on a photosensitizer with aggregation-induced emission (AIE) characteristics and conjugated to a fluorogenic rhodol dye via a singlet oxygen cleavable linker.

RSC Advances ◽  
2015 ◽  
Vol 5 (100) ◽  
pp. 81897-81904 ◽  
Author(s):  
Junliang Lv ◽  
Xin Zhang ◽  
Nana Li ◽  
Baoju Wang ◽  
Sailing He

Gold bipyramid-mediated singlet oxygen generation for photodynamic therapy of cancer cells in the optical biological window.


2020 ◽  
Vol 11 (14) ◽  
pp. 3636-3643 ◽  
Author(s):  
Jingjin Zhao ◽  
Mengbing Zou ◽  
Mengjiao Huang ◽  
Liangliang Zhang ◽  
Keqin Yang ◽  
...  

A multifunctional nanoprobe with singlet oxygen generation that can target tumors and mitochondria was developed for photodynamic therapy of tumors and monitoring mitochondrion pH changes in cancer cells by ratiometric fluorescence imaging.


2018 ◽  
Vol 47 (16) ◽  
pp. 5582-5588 ◽  
Author(s):  
Yun Ma ◽  
Shujun Zhang ◽  
Huanjie Wei ◽  
Yafang Dong ◽  
Liang Shen ◽  
...  

A novel soft salt based photosensitizer was successfully developed for application in photodynamic therapy of cancer cells for the first time.


2021 ◽  
Author(s):  
Esra Tanrıverdi Eçik ◽  
Onur BULUT ◽  
Hasan Hüseyin Kazan ◽  
Elif Şenkuytu ◽  
Bunyemin Cosut

Photodynamic therapy (PDT) is a promising strategy in cancer treatment with its relatively lower side effect profile. Undoubtedly, the key component of PDT is the photosensitizers with a high ability...


Author(s):  
Jiaxin Shen ◽  
Dandan Chen ◽  
Ye Liu ◽  
Guoyang Gao ◽  
Zhihe Liu ◽  
...  

Photodynamic therapy (PDT) is a promising method for cancer therapy and also may initiate unexpected damages to normal cells and tissues. Herein, we developed a near-infrared (NIR) light-activatable nanophotosensitizer, which...


2015 ◽  
Vol 51 (99) ◽  
pp. 17631-17632 ◽  
Author(s):  
Shigenobu Yano ◽  
Masami Naemura ◽  
Akio Toshimitsu ◽  
Motofusa Akiyama ◽  
Atsushi Ikeda ◽  
...  

Correction for ‘Efficient singlet oxygen generation from sugar pendant C60 derivatives for photodynamic therapy’ by Shigenobu Yano et al., Chem. Commun., 2015, DOI: 10.1039/c5cc07353g.


2019 ◽  
Vol 1 (6) ◽  
pp. 2250-2257 ◽  
Author(s):  
Xin Ting Zheng ◽  
Yee Ching Lai ◽  
Yen Nee Tan

We report a new way to engineer nanomaterials from biomolecules (N-dots) with bright fluorescence and high singlet oxygen generation towards theranostic applications.


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