scholarly journals Electrochemical detection of oxacillin resistance with SimpleStat: a low cost integrated potentiostat and sensor platform

2019 ◽  
Vol 11 (14) ◽  
pp. 1958-1965 ◽  
Author(s):  
Adrian Butterworth ◽  
Damion K. Corrigan ◽  
Andrew C. Ward

Testing outside the laboratory environment, such as point of care testing, is a rapidly evolving area with advances in the integration of sample handling, measurement and sensing elements widely reported.

Micromachines ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1464
Author(s):  
Florina Silvia Iliescu ◽  
Ana Maria Ionescu ◽  
Larisa Gogianu ◽  
Monica Simion ◽  
Violeta Dediu ◽  
...  

The deleterious effects of the coronavirus disease 2019 (COVID-19) pandemic urged the development of diagnostic tools to manage the spread of disease. Currently, the “gold standard” involves the use of quantitative real-time polymerase chain reaction (qRT-PCR) for SARS-CoV-2 detection. Even though it is sensitive, specific and applicable for large batches of samples, qRT-PCR is labour-intensive, time-consuming, requires trained personnel and is not available in remote settings. This review summarizes and compares the available strategies for COVID-19: serological testing, Point-of-Care Testing, nanotechnology-based approaches and biosensors. Last but not least, we address the advantages and limitations of these methods as well as perspectives in COVID-19 diagnostics. The effort is constantly focused on understanding the quickly changing landscape of available diagnostic testing of COVID-19 at the clinical levels and introducing reliable and rapid screening point of care testing. The last approach is key to aid the clinical decision-making process for infection control, enhancing an appropriate treatment strategy and prompt isolation of asymptomatic/mild cases. As a viable alternative, Point-of-Care Testing (POCT) is typically low-cost and user-friendly, hence harbouring tremendous potential for rapid COVID-19 diagnosis.


2008 ◽  
Vol 94 (2) ◽  
pp. 216-225 ◽  
Author(s):  
Marco Bianchessi ◽  
Sarah Burgarella ◽  
Marco Cereda

The development of new powerful applications and the improvement in fabrication techniques are promising an explosive growth in lab-on-chip use in the upcoming future. As the demand reaches significant levels, the semiconductor industry may enter in the field, bringing its capability to produce complex devices in large volumes, high quality and low cost. The lab-on-chip concept, when applied to medicine, leads to the point-of-care concept, where simple, compact and cheap instruments allow diagnostic assays to be performed quickly by untrained personnel directly at the patient's side. In this paper, some practical and economical considerations are made to support the advantages of point-of-care testing. A series of promising technologies developed by STMicroelectronics on lab-on-chips is also presented, mature enough to enter in the common medical practice. The possible use of these techniques for cancer research, diagnosis and treatment are illustrated together with the benefits offered by their implementation in point-of-care testing.


2015 ◽  
Vol 87 (15) ◽  
pp. 7738-7745 ◽  
Author(s):  
Jimmy Ming-Yuan Huang ◽  
Grace Henihan ◽  
Daniel Macdonald ◽  
Annette Michalowski ◽  
Kate Templeton ◽  
...  

2009 ◽  
Author(s):  
Albrecht Brandenburg ◽  
Franziska Curdt ◽  
Joerg Nestler ◽  
Thomas Otto ◽  
Kai Wunderlich ◽  
...  

Author(s):  
Curtis D. Chin ◽  
Sau Yin Chin ◽  
Tassaneewan Laksanasopin ◽  
Samuel K. Sia

2017 ◽  
Vol 9 (18) ◽  
pp. 2644-2653 ◽  
Author(s):  
Thiago Mazzu-Nascimento ◽  
Giorgio Gianini Morbioli ◽  
Luis Aparecido Milan ◽  
Diego Furtado Silva ◽  
Fabiana Cristina Donofrio ◽  
...  

Paper-based devices are an excellent match for low-cost point-of-care testing (POCT) tools.


Sensors ◽  
2020 ◽  
Vol 20 (21) ◽  
pp. 6073
Author(s):  
Chunyang Lu ◽  
Jintao Han ◽  
Xiaoyi Sun ◽  
Gen Yang

Circulating tumor cells (CTCs) are tumor cells that escaped from the primary tumor or the metastasis into the blood and they play a major role in the initiation of metastasis and tumor recurrence. Thus, it is widely accepted that CTC is the main target of liquid biopsy. In the past few decades, the separation of CTC based on the electrochemical method has attracted widespread attention due to its convenience, rapidness, low cost, high sensitivity, and no need for complex instruments and equipment. At present, CTC detection is not widely used in the clinic due to various reasons. Point-of-care CTC detection provides us with a possibility, which is sensitive, fast, cheap, and easy to operate. More importantly, the testing instrument is small and portable, and the testing does not require specialized laboratories and specialized clinical examiners. In this review, we summarized the latest developments in the electrochemical-based CTC detection and point-of-care CTC detection, and discussed the challenges and possible trends.


2013 ◽  
Vol 49 (32) ◽  
pp. 3294 ◽  
Author(s):  
Panpan Wang ◽  
Lei Ge ◽  
Shenguang Ge ◽  
Jinghua Yu ◽  
Mei Yan ◽  
...  

Lab on a Chip ◽  
2017 ◽  
Vol 17 (6) ◽  
pp. 1051-1059 ◽  
Author(s):  
Andrew S. Paterson ◽  
Balakrishnan Raja ◽  
Vinay Mandadi ◽  
Blane Townsend ◽  
Miles Lee ◽  
...  

Time-gated imaging on a smartphone of a lateral flow test strip run with persistent luminescent nanophosphors.


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