scholarly journals COvalent monolayer patterns in Microfluidics by PLasma etching Open Technology – COMPLOT

The Analyst ◽  
2020 ◽  
Vol 145 (5) ◽  
pp. 1629-1635 ◽  
Author(s):  
Stan B. J. Willems ◽  
Jaccoline Zegers ◽  
Anton Bunschoten ◽  
R. Martijn Wagterveld ◽  
Fijs W. B. van Leeuwen ◽  
...  

Plasma microcontact patterning (PμCP) and replica molding were combined to make PDMS/glass microfluidic devices with β-cyclodextrin (β-CD) patterns attached covalently on the glass surface inside microchannels.

2019 ◽  
Author(s):  
Stan B. J. Willems ◽  
Jaccoline Zegers ◽  
Anton Bunschoten ◽  
R. Martijn Wagterveld ◽  
Fijs W. B. van Leeuwen ◽  
...  

<p>By fabricating microfluidic devices via (covalent) plasma microcontact patterning (PµCP) and replica molding, we were able create β-CD patterns inside a microfluidic channel. Chemical reactivity and reusability of the devices were validated through host-guest interactions with diadamantane functionalized Cyanine 5 dye (Cy5-Ad<sub>2</sub>).<b></b></p>


2019 ◽  
Author(s):  
Stan B. J. Willems ◽  
Jaccoline Zegers ◽  
Anton Bunschoten ◽  
R. Martijn Wagterveld ◽  
Fijs W. B. van Leeuwen ◽  
...  

<p>By fabricating microfluidic devices via (covalent) plasma microcontact patterning (PµCP) and replica molding, we were able create β-CD patterns inside a microfluidic channel. Chemical reactivity and reusability of the devices were validated through host-guest interactions with diadamantane functionalized Cyanine 5 dye (Cy5-Ad<sub>2</sub>).<b></b></p>


2019 ◽  
Author(s):  
Stan B. J. Willems ◽  
Jaccoline Zegers ◽  
Anton Bunschoten ◽  
R. Martijn Wagterveld ◽  
Fijs W. B. van Leeuwen ◽  
...  

<p>By fabricating microfluidic devices via (covalent) plasma microcontact patterning (PµCP) and replica molding, we were able create β-CD patterns inside a microfluidic channel. Chemical reactivity and reusability of the devices were validated through host-guest interactions with diadamantane functionalized Cyanine 5 dye (Cy5-Ad<sub>2</sub>).<b></b></p>


BioTechniques ◽  
2021 ◽  
Author(s):  
Vedika J Shenoy ◽  
Chelsea ER Edwards ◽  
Matthew E Helgeson ◽  
Megan T Valentine

3D printing holds potential as a faster, cheaper alternative compared with traditional photolithography for the fabrication of microfluidic devices by replica molding. However, the influence of printing resolution and quality on device design and performance has yet to receive detailed study. Here, we investigate the use of 3D-printed molds to create staggered herringbone mixers (SHMs) with feature sizes ranging from ∼100 to 500 μm. We provide guidelines for printer calibration to ensure accurate printing at these length scales and quantify the impacts of print variability on SHM performance. We show that SHMs produced by 3D printing generate well-mixed output streams across devices with variable heights and defects, demonstrating that 3D printing is suitable and advantageous for low-cost, high-throughput SHM manufacturing.


2013 ◽  
Vol 421 ◽  
pp. 334-336 ◽  
Author(s):  
Yong Qiang Cheng ◽  
Cui Lian Guo ◽  
Yang Li ◽  
Bin Zhao ◽  
Xiao Cui

Paper-based microfluidic devices have recently received increasing attention as a potential platform for its low cost, portability and excellent compatibility with biological samples. A variety of fabrication technologies were employed, including simple photolithography, wax plotting, printing, inkjet etching, plasma etching and so on. Meanwhile, the potential applications of paper-based microfluidic devices in diagnostic, point-of-care (POC), and environmental monitoring were reported. We review the recent progress of fabrication technologies and the applications of paper-based microfluidic devices.


Lab on a Chip ◽  
2014 ◽  
Vol 14 (19) ◽  
pp. 3695-3699 ◽  
Author(s):  
Issac J. Micheal ◽  
Aditya J. Vidyasagar ◽  
Kiran Kumar Bokara ◽  
Naveen Kumar Mekala ◽  
Amit Asthana ◽  
...  

We present a facile, rapid and cost-effective way to fabricate microfluidic devices in laboratory atmosphere, named as “foil assisted replica molding” (FARM). This novel technique involves use of Al foil, pen and an X–Y plotter to create plano-concave microchannels. We have also demonstrated in vitro applications of these devices.


Lab on a Chip ◽  
2019 ◽  
Vol 19 (19) ◽  
pp. 3337-3343 ◽  
Author(s):  
N. Raj ◽  
V. Breedveld ◽  
D. W. Hess

A fully enclosed paper microfluidic device has been fabricated using pentafluoroethane (PFE) plasma deposition followed by O2 plasma etching.


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