Colorimetric switchable linker-based bioassay for ultrasensitive detection of prostate-specific antigen as a cancer biomarker

The Analyst ◽  
2019 ◽  
Vol 144 (14) ◽  
pp. 4439-4446 ◽  
Author(s):  
Jungwoo Hahn ◽  
Eunghee Kim ◽  
Youngsang You ◽  
Young Jin Choi

The use of colorimetric bioassays for protein detection is one of the most interesting diagnostic approaches, but their relatively poor detection limits have been a critical issue.

2014 ◽  
Vol 6 (22) ◽  
pp. 8878-8881 ◽  
Author(s):  
C. K. Tang ◽  
A. Vaze ◽  
J. F. Rusling

Inexpensive, reusable electrochemical chips were configured as immunosensors by using a filter paper disk equipped with antibodies. Rapid detection of cancer biomarker protein prostate specific antigen (PSA) in serum was achieved with 6 pg mL−1 detection in ∼15 min.


Small ◽  
2017 ◽  
Vol 13 (19) ◽  
pp. 1603944 ◽  
Author(s):  
Tiantian Hao ◽  
Xiaoling Wu ◽  
Liguang Xu ◽  
Liqiang Liu ◽  
Wei Ma ◽  
...  

1999 ◽  
pp. 1206-1211 ◽  
Author(s):  
ALEXANDER HAESE ◽  
EDITH HULAND ◽  
MARKUS GRAEFEN ◽  
PETER HAMMERER ◽  
JOACHIM NOLDUS ◽  
...  

2004 ◽  
Vol 5 (2) ◽  
Author(s):  
Maria Cristina Toledo Sawaya ◽  
Maria Regina Sawaya Rolim

O antígeno específico da próstata (PSA) é uma glicoproteína produzida pelo tecido prostático e secretada em altos níveis no fluido seminal. A PSA é amplamente utilizada como marcador prostático tumoral e como marcador forense. Ela foi descrita, primeiramente, como um antígeno específico da próstata e posteriormente sua presença foi observada em vários fluidos extraprostáticos. Esta revisão relata a evolução histórica da PSA e contém informações sobre os níveis de PSA já descritos em fluidos extraprostáticos. O propósito deste artigo é discutir se esses níveis podem interferir na identificação forense do semen. PROSTATE-SPECIFIC ANTIGEN IN BIOLOGICS FLUIDS: FORENSIC APLICATION Abstract Prostate-specific antigen (PSA) is a glycoprotein produced by prostatic tissue and secreted into the seminal plasma at high levels. PSA is widely used as a cancer biomarker and as a forensic marker. Originally PSA was described as a prostate-specific antigen. Later on PSA was observed in a variety of extraprostatic fluids. In this review we summarize its PSA evolutionary history and available informations about levels of PSA in nonprostatic fluids. This article aims to discuss if these levels ccould impair the forensic identification of semen.


2020 ◽  
Vol 1120 ◽  
pp. 36-42 ◽  
Author(s):  
Seyed Mohammad Taghdisi ◽  
Noor Mohammad Danesh ◽  
Morteza Alinezhad Nameghi ◽  
Mohammad Ramezani ◽  
Mona Alibolandi ◽  
...  

1999 ◽  
Vol 161 (4) ◽  
pp. 1206-1211 ◽  
Author(s):  
ALEXANDER HAESE ◽  
EDITH HULAND ◽  
MARKUS GRAEFEN ◽  
PETER HAMMERER ◽  
JOACHIM NOLDUS ◽  
...  

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