Surface-enhanced Raman spectroscopy (SERS) nanoprobes for ratiometric detection of cancer cells

2019 ◽  
Vol 7 (5) ◽  
pp. 815-822 ◽  
Author(s):  
Linhu Li ◽  
Mengling Liao ◽  
Yingfan Chen ◽  
Beibei Shan ◽  
Ming Li
Keyword(s):  
Raman Spectroscopy ◽  
Cancer Cells ◽  
Surface Enhanced Raman Spectroscopy ◽  
Expression Ratio ◽  
Raman Spectroscopic ◽  
Ratiometric Detection ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

A surface-enhanced Raman spectroscopic strategy is developed for ratiometric detection of cancer cells by quantifying the expression ratio of extracellular biomarkers.

Mapping gold nanoparticles on and in edible leaves in situ using surface enhanced Raman spectroscopy

RSC Advances ◽  
2016 ◽  
Vol 6 (65) ◽  
pp. 60152-60159 ◽  
Author(s):  
Zhiyun Zhang ◽  
Huiyuan Guo ◽  
Yingqing Deng ◽  
Baoshan Xing ◽  
Lili He
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Mapping Technique ◽  
Raman Spectroscopic ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Spinach Leaves

A surface enhanced Raman spectroscopic (SERS) mapping technique was applied to qualitatively detect and characterize gold nanoparticles on and in spinach leaves in situ.

Gold nanosponges (AuNS): a versatile nanostructure for surface-enhanced Raman spectroscopic detection of small molecules and biomolecules

The Analyst ◽  
2015 ◽  
Vol 140 (21) ◽  
pp. 7278-7282 ◽  
Author(s):  
Gregory Q. Wallace ◽  
Mariachiara S. Zuin ◽  
Mohammadali Tabatabaei ◽  
Pierangelo Gobbo ◽  
François Lagugné-Labarthet ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Small Molecules ◽  
Surface Enhanced Raman Spectroscopy ◽  
Raman Spectroscopic ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Prepared by simple pour and mix chemistry, gold nanosponges (AuNS) are versatile structures for surface-enhanced Raman spectroscopy (SERS).

Uptake of silver nanoparticles by DHA-treated cancer cells examined by surface-enhanced Raman spectroscopy in a microfluidic chip

Lab on a Chip ◽  
2017 ◽  
Vol 17 (7) ◽  
pp. 1306-1313 ◽  
Author(s):  
Zhimin Zhai ◽  
Fengqiu Zhang ◽  
Xiangyu Chen ◽  
Jie Zhong ◽  
Gang Liu ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Silver Nanoparticles ◽  
Cancer Cells ◽  
Microfluidic Chip ◽  
Surface Enhanced Raman Spectroscopy ◽  
Living Cells ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

This paper reports on the synthesis and application of biocompatible and sensitive SERS nanoparticles for the study of uptake of nanoparticles into living cells in a microfluidic chip through surface-enhanced Raman spectroscopy (SERS).

Branched gold nanoparticles on ZnO 3D architecture as biomedical SERS sensors

RSC Advances ◽  
2015 ◽  
Vol 5 (113) ◽  
pp. 93644-93651 ◽  
Author(s):  
S. Picciolini ◽  
N. Castagnetti ◽  
R. Vanna ◽  
D. Mehn ◽  
M. Bedoni ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Cancer Cells ◽  
Biomedical Application ◽  
Surface Enhanced Raman Spectroscopy ◽  
Drug Detection ◽  
3D Surface ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
3D Architecture

We present a new 3D surface-enhanced Raman spectroscopy substrate made of branched gold nanoparticles supported on ZnO tetrapods that was proved to be effective in different biomedical application such as drug detection and cancer cells analysis.

scholarly journals DNA sequencing by synthesis using 3′-O-azidomethyl nucleotide reversible terminators and surface-enhanced Raman spectroscopic detection

RSC Advances ◽  
2014 ◽  
Vol 4 (90) ◽  
pp. 49342-49346 ◽  
Author(s):  
Mirkó Palla ◽  
Wenjing Guo ◽  
Shundi Shi ◽  
Zengmin Li ◽  
Jian Wu ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Dna Sequencing ◽  
Surface Enhanced Raman Spectroscopy ◽  
Raman Shift ◽  
Azido Group ◽  
Raman Spectroscopic ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sequencing By Synthesis

DNA sequencing using surface enhanced Raman spectroscopy for the detection of the unique Raman shift of the azido group was demonstrated using 3′-O-azidomethyl nucleotide reversible terminators in polymerase reaction.

Scanning Electron Microscopy and Surface Enhanced Raman Spectroscopy Correlation Studies of Functionalized Composite Organic-Inorganic SERS Nanoparticles on Cancer Cells

2011 ◽  
Vol 1316 ◽  
Author(s):  
Ai Leen Koh ◽  
Robert Sinclair
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Raman Spectroscopy ◽  
Cancer Cells ◽  
Surface Enhanced Raman Spectroscopy ◽  
Excitation Light ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Intensity ◽  
Scanning Electron

ABSTRACTComposite Organic-Inorganic Nanoparticles (COINs) are a novel type of surface-enhanced Raman (SER) scattering nanoparticle formed by aggregating inorganic silver particles in the presence of a chosen organic molecule with a distinct Raman fingerprint. Binding between antibody-functionalized COINs and cells is detected primarily using Raman spectroscopy, which measures spectral shifts of the excitation light due to inelastic scattering. It has been suggested that the amount of antibody-conjugated COINs binding on cells will vary according to the antigen-expression levels in cells and will lead to changes in measured SERS intensities. COINs functionalized with antibodies CD54 and CD8 were conjugated to U937 and SupT1 cancer cells and investigated in this study. SERS intensity measurements were obtained from each of the four sample variants and normalized against control samples comprising non-antibody-functionalized COINs with cells. The amount of COINs binding on cells was determined using scanning electron microscopy (SEM) and correlated with the SER spectroscopy intensity. Although we found a positive correlation between the number of COINs binding to cells and their respective SERS intensity, this relationship is not one-to-one, nor does it appear to be linear. We demonstrated that SEM imaging and SER spectroscopy can complement each other to provide information about COINs binding onto cancer cells.

Brain tumour homogenates analysed by surface-enhanced Raman spectroscopy: Discrimination among healthy and cancer cells

2020 ◽  
Vol 231 ◽  
pp. 117769 ◽  
Author(s):  
Aneta Aniela Kowalska ◽  
Sylwia Berus ◽  
Łukasz Szleszkowski ◽  
Agnieszka Kamińska ◽  
Alicja Kmiecik ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Cancer Cells ◽  
Brain Tumour ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman
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