scholarly journals Cu-catalyzed enantioselective synthesis of tertiary benzylic copper complexes and their in situ addition to carbonyl compounds

2018 ◽  
Vol 9 (22) ◽  
pp. 4992-4998 ◽  
Author(s):  
Fengchang Cheng ◽  
Wenxin Lu ◽  
Wei Huang ◽  
Lu Wen ◽  
Mingfeng Li ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Carbonyl Compounds ◽  
Copper Complexes ◽  
Enantioselective Synthesis ◽  
Stereogenic Centers ◽  
Quaternary Stereogenic Centers

Catalytic chemo- and enantioselective generation of tertiary benzylic copper complexes from Cu–B(pin) (pin = pinacolato) additions to 1,1-disubstituted alkenes followed by in situ reactions with ketones and carboxylic acid phenol esters to construct multifunctional alkylboron compounds that contain quaternary stereogenic centers is presented.

scholarly journals Enantioselective synthesis of gem-diarylalkanes by transition metal-catalyzed asymmetric arylations (TMCAAr)

2018 ◽  
Vol 9 (3) ◽  
pp. 546-559 ◽  
Author(s):  
Tao Jia ◽  
Peng Cao ◽  
Jian Liao
Keyword(s):  
Transition Metal ◽  
Enantioselective Synthesis ◽  
Transfer Reactions ◽  
Stereogenic Centers ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed ◽  
Quaternary Stereogenic Centers ◽  
Aryl Transfer

To date, enantiomerically enriched molecules containing gem(1,1)-diaryl containing tertiary or quaternary stereogenic centers have been readily accessed by transition metal-catalyzed enantioselective or stereoconvergent aryl transfer reactions.

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