Enantioselective Synthesis of Nitroalkanes Bearing All-Carbon Quaternary Stereogenic Centers through Cu-Catalyzed Asymmetric Conjugate Additions

Jing Wu; Dawn M. Mampreian; Amir H. Hoveyda

doi:10.1021/ja050800f

Enantioselective Synthesis of Nitroalkanes Bearing All-Carbon Quaternary Stereogenic Centers through Cu-Catalyzed Asymmetric Conjugate Additions

Journal of the American Chemical Society ◽

10.1021/ja050800f ◽

2005 ◽

Vol 127 (13) ◽

pp. 4584-4585 ◽

Cited By ~ 123

Author(s):

Jing Wu ◽

Dawn M. Mampreian ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Conjugate Additions ◽

Stereogenic Centers ◽

Quaternary Stereogenic Centers

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Enantioselective Synthesis of All-Carbon Quaternary Stereogenic Centers by Catalytic Asymmetric Conjugate Additions of Alkyl and Aryl Aluminum Reagents to Five-, Six-, and Seven-Membered-Ring β-Substituted Cyclic Enones

Angewandte Chemie International Edition ◽

10.1002/anie.200802910 ◽

2008 ◽

Vol 47 (38) ◽

pp. 7358-7362 ◽

Cited By ~ 151

Author(s):

Tricia L. May ◽

M. Kevin Brown ◽

Amir H. Hoveyda

Keyword(s):

Membered Ring ◽

Enantioselective Synthesis ◽

Conjugate Additions ◽

Stereogenic Centers ◽

Cyclic Enones ◽

Catalytic Asymmetric ◽

Quaternary Stereogenic Centers

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Enantioselective Synthesis of Nitroalkanes Bearing All-Carbon Quaternary Stereogenic Centers Through Cu-Catalyzed Asymmetric Conjugate Additions.

ChemInform ◽

10.1002/chin.200533035 ◽

2005 ◽

Vol 36 (33) ◽

Author(s):

Jing Wu ◽

Dawn M. Mampreian ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Conjugate Additions ◽

Stereogenic Centers ◽

Quaternary Stereogenic Centers

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A Practical Method for Enantioselective Synthesis of All-Carbon Quaternary Stereogenic Centers Through NHC-Cu-Catalyzed Conjugate Additions of Alkyl- and Arylzinc Reagents to β-Substituted Cyclic Enones.

ChemInform ◽

10.1002/chin.200641024 ◽

2006 ◽

Vol 37 (41) ◽

Author(s):

Kang-sang Lee ◽

M. Kevin Brown ◽

Alexander W. Hird ◽

Amir H. Hoveyda

Keyword(s):

Practical Method ◽

Enantioselective Synthesis ◽

Conjugate Additions ◽

Stereogenic Centers ◽

Cyclic Enones ◽

Quaternary Stereogenic Centers

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Enantioselective Synthesis of All-Carbon Quaternary Stereogenic Centers by Catalytic Asymmetric Conjugate Additions of Alkyl and Aryl Aluminum Reagents to Five-, Six-, and Seven-Membered-Ring β-Substituted Cyclic Enones

Angewandte Chemie ◽

10.1002/ange.200802910 ◽

2008 ◽

Vol 120 (38) ◽

pp. 7468-7472 ◽

Cited By ~ 57

Author(s):

Tricia L. May ◽

M. Kevin Brown ◽

Amir H. Hoveyda

Keyword(s):

Membered Ring ◽

Enantioselective Synthesis ◽

Conjugate Additions ◽

Stereogenic Centers ◽

Cyclic Enones ◽

Catalytic Asymmetric ◽

Quaternary Stereogenic Centers

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A Practical Method for Enantioselective Synthesis of All-Carbon Quaternary Stereogenic Centers through NHC-Cu-Catalyzed Conjugate Additions of Alkyl- and Arylzinc Reagents to β-Substituted Cyclic Enones

Journal of the American Chemical Society ◽

10.1021/ja062061o ◽

2006 ◽

Vol 128 (22) ◽

pp. 7182-7184 ◽

Cited By ~ 185

Author(s):

Kang-sang Lee ◽

M. Kevin Brown ◽

Alexander W. Hird ◽

Amir H. Hoveyda

Keyword(s):

Practical Method ◽

Enantioselective Synthesis ◽

Conjugate Additions ◽

Stereogenic Centers ◽

Cyclic Enones ◽

Quaternary Stereogenic Centers

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ChemInform Abstract: Enantioselective Synthesis of All-Carbon Quaternary Stereogenic Centers by Catalytic Asymmetric Conjugate Additions of Alkyl and Aryl Aluminum Reagents to Five-, Six-, and Seven-Membered-Ring β-Substituted Cyclic Enones.

ChemInform ◽

10.1002/chin.200902065 ◽

2009 ◽

Vol 40 (2) ◽

Author(s):

Tricia L. May ◽

M. Kevin Brown ◽

Amir H. Hoveyda

Keyword(s):

Membered Ring ◽

Enantioselective Synthesis ◽

Conjugate Additions ◽

Stereogenic Centers ◽

Cyclic Enones ◽

Catalytic Asymmetric ◽

Quaternary Stereogenic Centers

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Enantioselective Synthesis of Quaternary Carbon Stereogenic Centers through Copper-Catalyzed Conjugate Additions of Aryl- and Alkylaluminum Reagents to Acyclic Trisubstituted Enones

Angewandte Chemie International Edition ◽

10.1002/anie.201304035 ◽

2013 ◽

Vol 52 (31) ◽

pp. 8156-8159 ◽

Cited By ~ 46

Author(s):

Jennifer A. Dabrowski ◽

Matthew T. Villaume ◽

Amir H. Hoveyda

Keyword(s):

Enantioselective Synthesis ◽

Quaternary Carbon ◽

Conjugate Additions ◽

Stereogenic Centers

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Organocatalyzed Enantioselective Synthesis of Nitroalkanes Bearing All-Carbon Quaternary Stereogenic Centers through Conjugate Addition of Acetone Cyanohydrin

Synlett ◽

10.1055/s-2008-1078496 ◽

2008 ◽

Vol 2008 (12) ◽

pp. 1857-1861 ◽

Cited By ~ 5

Author(s):

Mariafrancesca Fochi ◽

Alfredo Ricci ◽

Luca Bernardi ◽

Francesco Fini

Keyword(s):

Conjugate Addition ◽

Enantioselective Synthesis ◽

Acetone Cyanohydrin ◽

Stereogenic Centers ◽

Quaternary Stereogenic Centers

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Enantioselective synthesis of gem-diarylalkanes by transition metal-catalyzed asymmetric arylations (TMCAAr)

Chemical Science ◽

10.1039/c7sc03404k ◽

2018 ◽

Vol 9 (3) ◽

pp. 546-559 ◽

Cited By ~ 30

Author(s):

Tao Jia ◽

Peng Cao ◽

Jian Liao

Keyword(s):

Transition Metal ◽

Enantioselective Synthesis ◽

Transfer Reactions ◽

Stereogenic Centers ◽

Transition Metal Catalyzed ◽

Metal Catalyzed ◽

Quaternary Stereogenic Centers ◽

Aryl Transfer

To date, enantiomerically enriched molecules containing gem(1,1)-diaryl containing tertiary or quaternary stereogenic centers have been readily accessed by transition metal-catalyzed enantioselective or stereoconvergent aryl transfer reactions.

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Enantioselective synthesis of cyclopropane aminoalcohols containing quaternary stereogenic centers

Tetrahedron Asymmetry ◽

10.1016/s0957-4166(99)00463-2 ◽

1999 ◽

Vol 10 (21) ◽

pp. 4245-4260 ◽

Cited By ~ 16

Author(s):

Joan Rifé ◽

Rosa M. Ortuño

Keyword(s):

Enantioselective Synthesis ◽

Stereogenic Centers ◽

Quaternary Stereogenic Centers

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