scholarly journals Correction: A study on a telo21 G-quadruplex DNA specific binding ligand: enhancing the molecular recognition ability via the amino group interactions

RSC Advances ◽  
2018 ◽  
Vol 8 (41) ◽  
pp. 22931-22931
Author(s):  
Dongli Li ◽  
Jin-Qiang Hou ◽  
Wei Long ◽  
Yu-Jing Lu ◽  
Wing-Leung Wong ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Specific Binding ◽  
Amino Group ◽  
Group Interactions ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Recognition Ability

Correction for ‘A study on a telo21 G-quadruplex DNA specific binding ligand: enhancing the molecular recognition ability via the amino group interactions’ by Dongli Li et al., RSC Adv., 2018, 8, 20222–20227.

scholarly journals A study on a telo21 G-quadruplex DNA specific binding ligand: enhancing the molecular recognition ability via the amino group interactions

RSC Advances ◽  
2018 ◽  
Vol 8 (36) ◽  
pp. 20222-20227 ◽  
Author(s):  
Dongli Li ◽  
Jin-Qiang Hou ◽  
Wei Long ◽  
Yu-Jing Lu ◽  
Wing-Leung Wong ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Specific Binding ◽  
Amino Group ◽  
Amino Groups ◽  
Group Interactions ◽  
Quadruplex Dna ◽  
Fluorescent Signal ◽  
Hydrogen Bonding Interactions ◽  
G Quadruplex ◽  
Recognition Ability

A significant fluorescent signal enhancement attributed to hydrogen-bonding interactions through the amino groups of a small binding ligand in the G-quartets (binding energy: −6.2 kcal mol−1).

Molecular recognition of parallel quadruplex [d-(TTGGGGT)]4 by mitoxantrone: binding with 1 : 4 stoichiometry leads to telomerase inhibition

RSC Advances ◽  
2016 ◽  
Vol 6 (75) ◽  
pp. 71652-71661 ◽  
Author(s):  
Tarikere Palakshan Pradeep ◽  
Sweta Tripathi ◽  
Ritu Barthwal
Keyword(s):  
Molecular Recognition ◽  
Thermal Stabilization ◽  
Cancer Drug ◽  
Telomerase Inhibition ◽  
Quadruplex Dna ◽  
Anti Cancer ◽  
G Quadruplex ◽  
Cd Studies

NMR and CD studies show that anti-cancer drug mitoxantrone (MTX) binds to parallel G-quadruplex DNA [d-(TTGGGGT)4] as stacked dimer at grooves leading to increase in thermal stabilization of DNA by ~25 °C and inhibits telomerase with IC50 = 2 μM.

scholarly journals The Thermodynamic Effects of Ligand Structure on the Molecular Recognition of Mono- and Biruthenium Polypyridyl Complexes with G-Quadruplex DNA

2017 ◽  
Vol 2017 (33) ◽  
pp. 3953-3960 ◽  
Author(s):  
Clinton G. Mikek ◽  
Venkata R. Machha ◽  
Jake C. White ◽  
Logan R. Martin ◽  
Savannah J. West ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Polypyridyl Complexes ◽  
Quadruplex Dna ◽  
Ligand Structure ◽  
G Quadruplex ◽  
Thermodynamic Effects

Molecular recognition of G-quadruplex DNA by Pheophorbide a

2021 ◽  
Author(s):  
China Okamoto ◽  
Atsuya Momotake ◽  
Masami Kobayashi ◽  
Yasuhiko Yamamoto
Keyword(s):  
Molecular Recognition ◽  
Pheophorbide A ◽  
Quadruplex Dna ◽  
G Quadruplex

Targeting G-quadruplex DNA and B-DNA with a natural alkaloid: a comparative spectroscopic study

RSC Advances ◽  
2016 ◽  
Vol 6 (111) ◽  
pp. 109846-109856 ◽  
Author(s):  
Paulami Mandal ◽  
Maitree Bhattacharya ◽  
Joydeep Chowdhury
Keyword(s):  
Molecular Recognition ◽  
Spectroscopic Study ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Natural Alkaloid

Different modes of binding of natural alkaloid harmine with G-quadruplex DNA and B-DNA: key roles in molecular recognition.

G-Quadruplex DNA- and RNA-Specific-Binding Proteins Engineered from the RGG Domain of TLS/FUS

2015 ◽  
Vol 10 (11) ◽  
pp. 2564-2569 ◽  
Author(s):  
Kentaro Takahama ◽  
Arisa Miyawaki ◽  
Takumi Shitara ◽  
Keita Mitsuya ◽  
Masayuki Morikawa ◽  
...  
Keyword(s):  
Binding Proteins ◽  
Specific Binding ◽  
Quadruplex Dna ◽  
Dna And Rna ◽  
G Quadruplex

Hybrid Imidazole-Pyridine Derivatives: An Approach to Novel Anticancer DNA Intercalators

2020 ◽  
Vol 27 (1) ◽  
pp. 154-169 ◽  
Author(s):  
Claudiu N. Lungu ◽  
Bogdan Ionel Bratanovici ◽  
Maria Mirabela Grigore ◽  
Vasilichia Antoci ◽  
Ionel I. Mangalagiu
Keyword(s):  
Experimental Data ◽  
Antimicrobial Properties ◽  
Qsar Model ◽  
Therapeutic Effectiveness ◽  
Computational Results ◽  
Pyridine Derivatives ◽  
Quadruplex Dna ◽  
Dna Intercalators ◽  
Structure Activity ◽  
G Quadruplex

Lack of specificity and subsequent therapeutic effectiveness of antimicrobial and antitumoral drugs is a common difficulty in therapy. The aim of this study is to investigate, both by experimental and computational methods, the antitumoral and antimicrobial properties of a series of synthesized imidazole-pyridine derivatives. Interaction with three targets was discussed: Dickerson-Drew dodecamer (PDB id 2ADU), G-quadruplex DNA string (PDB id 2F8U) and DNA strain in complex with dioxygenase (PDB id 3S5A). Docking energies were computed and represented graphically. On them, a QSAR model was developed in order to further investigate the structure-activity relationship. Results showed that synthesized compounds have antitumoral and antimicrobial properties. Computational results agreed with the experimental data.

Emerging Role of G-quadruplex DNA as Target in Anticancer Therapy

2017 ◽  
Vol 22 (44) ◽  
pp. 6612-6624 ◽  
Author(s):  
Graziella Cimino-Reale ◽  
Nadia Zaffaroni ◽  
Marco Folini
Keyword(s):  
Anticancer Therapy ◽  
Quadruplex Dna ◽  
G Quadruplex
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