A strategy for the molecular design of aggregation-induced emission units further modified by substituents

2018 ◽  
Vol 2 (6) ◽  
pp. 1175-1183 ◽  
Author(s):  
Zhe Peng ◽  
Yingchun Ji ◽  
Zihan Huang ◽  
Bin Tong ◽  
Jianbing Shi ◽  
...  
Keyword(s):  
Molecular Design ◽  
Aggregation Induced Emission

Aryl-substituted pyrrolo[3,2-b]pyrrole as a new AIE unit modified by different electron-withdrawing or electron-donating substituents to obtain AIEgens.

Highly efficient photosensitizers with aggregation-induced emission characteristics obtained through precise molecular design

2017 ◽  
Vol 53 (62) ◽  
pp. 8727-8730 ◽  
Author(s):  
Shidang Xu ◽  
Wenbo Wu ◽  
Xiaolei Cai ◽  
Chong-Jing Zhang ◽  
Youyong Yuan ◽  
...  
Keyword(s):  
Molecular Design ◽  
Emission Characteristics ◽  
Aggregation Induced Emission ◽  
Absorption And Emission ◽  
Highly Efficient ◽  
Tunable Absorption

Through precise molecular design, predictable properties including photosensitizing efficacy, tunable absorption and emission wavelengths and aggregation-induced emission characteristics were achieved.

Real-Time Visualization and Monitoring of Physiological Dynamics by Aggregation-Induced Emission Luminogens (AIEgens)

2021 ◽  
Vol 14 (1) ◽  
pp. 413-435
Author(s):  
Xuewen He ◽  
Jacky W.Y. Lam ◽  
Ryan T.K. Kwok ◽  
Ben Zhong Tang
Keyword(s):  
Real Time ◽  
Near Infrared ◽  
Molecular Design ◽  
High Sensitivity ◽  
Microwave Emission ◽  
Excellent Performance ◽  
Disease Evolution ◽  
Aggregation Induced Emission ◽  
Long Wavelength ◽  
Real Time Visualization

Physiological dynamics in living cells and tissues are crucial for maintenance and regulation of their normal activities and functionalities. Tiny fluctuations in physiological microenvironments can leverage significant influences on cell growth, metabolism, differentiation, and apoptosis as well as disease evolution. Fluorescence imaging based on aggregation-induced emission luminogens (AIEgens) exhibits superior advantages in real-time sensing and monitoring of the physiological dynamics in living systems, including its unique properties such as high sensitivity and rapid response, flexible molecular design, and versatile nano- to mesostructural fabrication. The introduction of canonic AIEgens with long-wavelength, near-infrared, or microwave emission, persistent luminescence, and diversified excitation source (e.g., chemo- or bioluminescence) offers researchers a tool to evaluate the resulting molecules with excellent performance in response to subtle fluctuations in bioactivities with broader dimensionalities and deeper hierarchies.

Rational molecular design of aggregation-induced emission cationic Ir(iii) phosphors achieving supersensitive and selective detection of nitroaromatic explosives

2017 ◽  
Vol 5 (41) ◽  
pp. 10847-10854 ◽  
Author(s):  
Li-Li Wen ◽  
Xue-Gang Hou ◽  
Guo-Gang Shan ◽  
Wei-Lin Song ◽  
Shu-Ran Zhang ◽  
...  
Keyword(s):  
Molecular Design ◽  
Selective Detection ◽  
Nitroaromatic Explosives ◽  
Aggregation Induced Emission ◽  
Rational Molecular Design

Employing AIE-active cationic Ir(iii) phosphors as sensors, the supersensitive and selective detection of TNP was achieved.

Advances in fluorescent sensors for β-galactosidase

2021 ◽  
Author(s):  
Meng Li ◽  
Mengqing Yang ◽  
Wei-Hong Zhu
Keyword(s):  
Fluorescent Probes ◽  
Molecular Design ◽  
Design Strategy ◽  
Fluorescent Sensors ◽  
Detection Accuracy ◽  
Biological Applications ◽  
Accuracy Enhancement ◽  
Aggregation Induced Emission

This minireview summarizes advances in the molecular design strategy and biological applications of fluorescent probes for β-galactosidase (β-Gal), focusing on detection accuracy enhancement and aggregation-induced emission for background minimization.

Aggregation-induced emission luminogens for RONS sensing

2020 ◽  
Vol 8 (16) ◽  
pp. 3357-3370 ◽  
Author(s):  
Jun Dai ◽  
Chong Duan ◽  
Yu Huang ◽  
Xiaoding Lou ◽  
Fan Xia ◽  
...  
Keyword(s):  
Molecular Design ◽  
Living Systems ◽  
Aggregation Induced Emission ◽  
Sensing Mechanism

The development of AIE bioprobes for RONS sensing in living systems is now summarized. We discuss some representative examples of AIEgen based bioprobes in terms of their molecular design, sensing mechanism and sensitive sensing in vitro and in vivo.

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