scholarly journals Reflectance confocal microscopy in the diagnosis of pigmented macules of the face: differential diagnosis and margin definition

2019 ◽  
Vol 18 (5) ◽  
pp. 963-969 ◽  
Author(s):  
Francesca Farnetani ◽  
Marco Manfredini ◽  
Johanna Chester ◽  
Silvana Ciardo ◽  
Salvador Gonzalez ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Confocal Microscopy ◽  
State Of The Art ◽  
Correct Diagnosis ◽  
The State ◽  
Reflectance Confocal Microscopy ◽  
Diagnostic Algorithms ◽  
Diagnosis And Management ◽  
The Face ◽  
Standardized Terminology

Here we review the state-of-the-art of RCM morphologic descriptors, standardized terminology, and diagnostic algorithms for the assessment of pigmented macules of the face, for their correct diagnosis and management.

scholarly journals The Differential Diagnosis of Hypopigmented Mycosis Fungoides and Vitiligo With Reflectance Confocal Microscopy: A Preliminary Study

2021 ◽  
Vol 7 ◽  
Author(s):  
Huaxu Liu ◽  
Leilei Wang ◽  
Yan Lin ◽  
Xiaofeng Shan ◽  
Min Gao
Keyword(s):  
Differential Diagnosis ◽  
Confocal Microscopy ◽  
Mycosis Fungoides ◽  
Early Stage ◽  
Reflectance Confocal Microscopy ◽  
Inflammatory Conditions ◽  
Dark Space ◽  
Superficial Dermis ◽  
Melanin Contents

Objective: To investigate the role of reflectance confocal microscopy (RCM) in the differential diagnosis of hypopigmented mycosis fungoides (HMF) and vitiligo.Methods: Cases with persistent hypopigmented patches, suspicious of early stage vitiligo, or HMF were imaged with RCM. The melanin contents and inflammatory conditions of the epidermis and superficial dermis of the lesions were compared with the same layers of the adjacent skin, and then, the imaged lesions were biopsied and analyzed by histology.Results: 15 cases were enrolled in this study, and based on the RCM findings, there was just slight or moderate reduction of melanin but no melanin absence in the basal cell layer of HMF lesions. The finding of monomorphous weakly refractile, oval to round cells on the basis of vesicle-like dark space was clearly elucidated in the epidermis of the lesions by RCM, which indicates the Pautrier's microabscesses on histopathology. Among those 15 cases, 13 cases were identified as HMF, and the other two cases were vitiligo, based on RCM findings, which were confirmed by histology analysis.Conclusions: The RCM findings correlated well with histology results in the screening of HMF, which indicates the RCM is an important tool in the early detection and differential diagnosis of HMF.

scholarly journals Liderazgo actual: una percepción de estudiantes de educación superior

2019 ◽  
pp. 1-12
Author(s):  
Raquel Ivonne Velasco-Cepeda ◽  
Yesenia Clark-Mendívil
Keyword(s):  
State Of The Art ◽  
Ethical Dilemmas ◽  
The State ◽  
Quantitative Approach ◽  
Future Research ◽  
Ethical Problems ◽  
Educacion Superior ◽  
Moral Conduct ◽  
The Face ◽  
Current Leadership

Objective of the study to identify students' perception of the degree in administration about leadership in the face of current challenges, the values and qualities required by today's leader, as well as the areas where ethical dilemmas are, for the development of competences that affect the solution of problems of their profession. Non-experimental, transectional, descriptive, quantitative approach research. One section of the instrument had a scale of 5 response categories, the second with 3: very important, regularly important and unimportant; third with three: many, some and none. The results before the current problems obtained the highest means in: the current leadership needs ethical and moral conduct with 4.41, society has not become aware of its great problems with 4.23; people are disappointed by the unwillingness of the authorities with 4.21. On the perception of the values and qualities of the leader: be honest 1.13, be clear about the objectives you want to achieve 1.14 and ability to face challenges 1.16. The areas where ethical problems are found: 1.40 in education, economic 1.48, and 1.51 in leadership. The study contributes to future research and the state of the art.

Majocchi's granuloma on the face: dermoscopy and reflectance confocal microscopy

2019 ◽  
Vol 58 (9) ◽  
Author(s):  
Vincenzo Piccolo ◽  
Eugenia Veronica Di Brizzi ◽  
Teresa Russo ◽  
Elvira Moscarella ◽  
Ticiana Diniz ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
The Face ◽  
Majocchi’S Granuloma

“The Enthusiasm Expressed by Our Industry Friends”

Vulcan ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 100-124
Author(s):  
Adam Givens
Keyword(s):  
Long Range ◽  
State Of The Art ◽  
The State ◽  
Next Generation ◽  
Short Term ◽  
Us Army ◽  
The Face ◽  
Long Term Consequences ◽  
Fait Accompli

Abstract This article analyzes the groundbreaking 1952 plan by US Army leadership to develop a sizeable cargo helicopter program in the face of interservice opposition. It examines the influence that decision had in the next decade on the Army, the helicopter industry, and vtol technology. The Army’s procurement of large helicopters that could transport soldiers and materiel was neither a fait accompli nor based on short-term needs. Rather, archival records reveal that the decision was based on long-range concerns about the postwar health of the helicopter industry, developing the state of the art, and fostering new doctrinal concepts. The procurement had long-term consequences. Helicopters became central to Army war planning, and the ground service’s needs dictated the next generation of helicopter designs. That technology made possible the revolutionary airmobility concept that the Army took into Vietnam and also led to a flourishing commercial helicopter field.

The intersubjective turn

2018 ◽  
pp. 452-468
Author(s):  
Hanne De Jaegher
Keyword(s):  
Social Interaction ◽  
Subject Matter ◽  
State Of The Art ◽  
The State ◽  
Levels Of Explanation ◽  
Critical Awareness ◽  
Interaction Processes ◽  
The Face

I outline five criteria for an enactive account of intersubjectivity. First, it should do justice to social interaction processes and to subjectivity in its experiential, bodily, existential, and historico-sociocultural complexity. Second, an integrative intersubjectivity framework should connect physiological, neural, interactional, linguistic, and societal aspects and levels of explanation. This requires concepts and methodologies that span several different disciplines. Third, it should encourage applications and dialogue with experts in other sectors, such as teachers and therapists. Fourth, it should recognize the values that underlie it, so it can serve critical awareness of how it influences and is influenced by societal institutions and norms. Finally, because its subject matter is the ways in which people understand and deal with each other, it should be prepared to deal with ethical questions and dimensions. Then, I investigate how the state of the art in enactive intersubjectivity research fares in the face of these criteria.

scholarly journals Skin strata delineation in reflectance confocal microscopy images using recurrent convolutional networks with attention

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alican Bozkurt ◽  
Kivanc Kose ◽  
Jaume Coll-Font ◽  
Christi Alessi-Fox ◽  
Dana H. Brooks ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
State Of The Art ◽  
Reflectance Confocal Microscopy ◽  
Convolutional Networks ◽  
Non Invasive ◽  
Extensive Training ◽  
Fold Reduction ◽  
Previous State ◽  
Microscopy Images ◽  
Field View

AbstractReflectance confocal microscopy (RCM) is an effective non-invasive tool for cancer diagnosis. However, acquiring and reading RCM images requires extensive training and experience, and novice clinicians exhibit high discordance in diagnostic accuracy. Quantitative tools to standardize image acquisition could reduce both required training and diagnostic variability. To perform diagnostic analysis, clinicians collect a set of RCM mosaics (RCM images concatenated in a raster fashion to extend the field view) at 4–5 specific layers in skin, all localized in the junction between the epidermal and dermal layers (dermal-epidermal junction, DEJ), necessitating locating that junction before mosaic acquisition. In this study, we automate DEJ localization using deep recurrent convolutional neural networks to delineate skin strata in stacks of RCM images collected at consecutive depths. Success will guide to automated and quantitative mosaic acquisition thus reducing inter operator variability and bring standardization in imaging. Testing our model against an expert labeled dataset of 504 RCM stacks, we achieved $$88.07\%$$ 88.07 % classification accuracy and nine-fold reduction in the number of anatomically impossible errors compared to the previous state-of-the-art.

Sign in / Sign up

Export Citation Format

Share Document