Reflectance confocal microscopy in pediatric dermatology: A state‐of‐the‐art review

2021 ◽  
Author(s):  
Randy F. Ko ◽  
Aimee C. Smidt ◽  
John R. Durkin
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alican Bozkurt ◽  
Kivanc Kose ◽  
Jaume Coll-Font ◽  
Christi Alessi-Fox ◽  
Dana H. Brooks ◽  
...  

AbstractReflectance confocal microscopy (RCM) is an effective non-invasive tool for cancer diagnosis. However, acquiring and reading RCM images requires extensive training and experience, and novice clinicians exhibit high discordance in diagnostic accuracy. Quantitative tools to standardize image acquisition could reduce both required training and diagnostic variability. To perform diagnostic analysis, clinicians collect a set of RCM mosaics (RCM images concatenated in a raster fashion to extend the field view) at 4–5 specific layers in skin, all localized in the junction between the epidermal and dermal layers (dermal-epidermal junction, DEJ), necessitating locating that junction before mosaic acquisition. In this study, we automate DEJ localization using deep recurrent convolutional neural networks to delineate skin strata in stacks of RCM images collected at consecutive depths. Success will guide to automated and quantitative mosaic acquisition thus reducing inter operator variability and bring standardization in imaging. Testing our model against an expert labeled dataset of 504 RCM stacks, we achieved $$88.07\%$$ 88.07 % classification accuracy and nine-fold reduction in the number of anatomically impossible errors compared to the previous state-of-the-art.


2019 ◽  
Vol 18 (5) ◽  
pp. 963-969 ◽  
Author(s):  
Francesca Farnetani ◽  
Marco Manfredini ◽  
Johanna Chester ◽  
Silvana Ciardo ◽  
Salvador Gonzalez ◽  
...  

Here we review the state-of-the-art of RCM morphologic descriptors, standardized terminology, and diagnostic algorithms for the assessment of pigmented macules of the face, for their correct diagnosis and management.


Author(s):  
Arianna Rizzo ◽  
Diletta Fiorani ◽  
Laura Lazzeri ◽  
Paolo Taddeucci ◽  
Pietro Rubegni ◽  
...  

2021 ◽  
Vol 14 (1) ◽  
pp. e240507
Author(s):  
Mihai Lupu ◽  
Vlad Mihai Voiculescu ◽  
Cristina Vajaitu ◽  
Olguta Anca Orzan

Author(s):  
Cristian Navarrete‐Dechent ◽  
Miguel Cordova ◽  
Saud Aleissa ◽  
Alexander Shoushtari ◽  
Travis J. Hollmann ◽  
...  

Author(s):  
Samavia Khan ◽  
Nadiya Chuchvara ◽  
Jennifer Cucalon ◽  
Attiya Haroon ◽  
Babar Rao

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