Lactoferrin-conjugated pH and redox-sensitive polymersomes based on PEG-S-S-PLA-PCL-OH boost delivery of bacosides to the brain

Nanoscale ◽  
2018 ◽  
Vol 10 (37) ◽  
pp. 17781-17798 ◽  
Author(s):  
Kritika Goyal ◽  
Arpita Konar ◽  
B. S. Hemanth Kumar ◽  
Veena Koul

In the present study, engineered lactoferrin (Lf)-conjugated pH and redox-sensitive polymersomes derived from the triblock copolymer polyethylene glycol-S-S-polylactic acid-polycaprolactone (PEG-S-S-PLA-PCL-OH) have been used to deliver bacosides to the brain.

RSC Advances ◽  
2020 ◽  
Vol 10 (69) ◽  
pp. 42120-42127
Author(s):  
Ruilong Li ◽  
Yifan Wu ◽  
Zhuyu Bai ◽  
Jianbing Guo ◽  
Xiaolang Chen

In this work, the poly(d-lactic acid)–polyethylene glycol–poly(d-lactic acid) (PDLA–PEG–PDLA) triblock copolymer as a novel modification agent was incorporated into poly(l-lactic acid) (PLLA) to improve the thermal and mechanical properties of PLLA.


2016 ◽  
Vol 116 (01) ◽  
pp. 54-58
Author(s):  
B. Ozpolat ◽  
N. Gunal ◽  
Z. Pekcan ◽  
E. S. Ayva ◽  
O. Bozdogan ◽  
...  

2019 ◽  
Vol 136 (26) ◽  
pp. 47709 ◽  
Author(s):  
Haibo Long ◽  
Zhiqiang Wu ◽  
Qianqian Dong ◽  
Yuting Shen ◽  
Wuyi Zhou ◽  
...  

2021 ◽  
Vol 889 ◽  
pp. 44-49
Author(s):  
Yeng Fong Shih ◽  
Zheng Ting Chen ◽  
Wei Lun Lin ◽  
Po Chun Chiu ◽  
Chin Hsien Chiang ◽  
...  

The purpose of this research is to develop a new type of environmentally friendly container which has thermostatic effect and is biodegradable. This study is based on polylactic acid (PLA) and maleic anhydride grafted polybutylene succinate (MAPBS). Subsequently, the diatomite which adsorbed polyethylene glycol (PEG) was added to prepare a thermostatic biodegradable composite. The addition of MAPBS is to improve the compatibility between PLA and diatomite. In addition, the thermostatic effect, tensile strength, thermal deformation temperature and impact strength of the composite were investigated.


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