A smart sensor for rapid detection of lethal hydrazine in human blood and drinking water

2019 ◽  
Vol 43 (8) ◽  
pp. 3303-3308 ◽  
Author(s):  
Sima Paul ◽  
Rajesh Nandi ◽  
Kakali Ghoshal ◽  
Maitree Bhattacharyya ◽  
Dilip K. Maiti

A newly designed and synthesized probe showed good cell permeability, low cytotoxicity, fast fluorogenic recognition, and “naked-eye” detection of a lethal health hazard, hydrazine, even at concentrations significantly below the TLV levels present in living cells, drinking water and industrial effluent.

2018 ◽  
Vol 16 (47) ◽  
pp. 9197-9203 ◽  
Author(s):  
Chunchao Tang ◽  
Lei Jin ◽  
Yuxing Lin ◽  
Jing Su ◽  
Yingai Sun ◽  
...  

We report a new BL probe,TyrBP-3, which not only exhibits high sensitivity and selectivity for imaging tyrosinase in vitro, and good cell-permeability for detecting tyrosinase in living cells, but can also visualize the level of tyrosinase activity in tumors of living animals.


RSC Advances ◽  
2015 ◽  
Vol 5 (125) ◽  
pp. 103350-103357 ◽  
Author(s):  
Sandip Mandal ◽  
Animesh Sahana ◽  
Arnab Banerjee ◽  
Damir A. Safin ◽  
Maria G. Babashkina ◽  
...  

A rhodamine–pyridine conjugate, REDA-2PC, can selectively monitor NCS− in human embryonic kidney cells 293. Visible light excitable probe allows fluorescence and naked eye detection of nanomolar NCS−.


Author(s):  
Aron Hakonen ◽  
Niklas Strömberg

Drinking water contamination of lead from various environmental sources, leaching consumer products and intrinsic water-pipe infrastructure is still today a matter of great concern. Therefore, new highly sensitive and convenient Pb2+ measurement schemes are necessary, especially for in-situ measurements at a low-cost. Within this work dye/ionophore/Pb2+ co-extraction and effective water phase de-colorization was utilized for highly sensitive lead measurements and sub-ppb naked-eye detection. A low-cost ionophore Benzo-18-Crown-6-ether was used, and a simple test-tube mix and separate procedure was developed. Instrumental detection limits were in the low ppt region (LOD=3, LOQ=10), and naked-eye detection was 500 ppt. Note, however, that this sensing scheme still has improvement potential as concentrations of fluorophore and ionophore were not optimized. Artificial tap-water samples, leached by a standardized method, demonstrated drinking water application. Implications for this method are convenient in-situ lead ion measurements.


2015 ◽  
Vol 39 (6) ◽  
pp. 4790-4795 ◽  
Author(s):  
Meipan Yang ◽  
Wenfei Meng ◽  
Qingli Ding ◽  
Na Su ◽  
Xiaojing Liu ◽  
...  

Novel fluorescent probes for Fe3+ and their application of imaging in living cells.


2014 ◽  
Vol 50 (49) ◽  
pp. 6443-6446 ◽  
Author(s):  
Lei Chen ◽  
Junchen Wu ◽  
Carsten Schmuck ◽  
He Tian

A bis-spiropyran functionalized peptide1, which exhibits good cell-permeability, biocompatibility and low cytotoxicity, has been developed for lysosomal tracking.


2012 ◽  
Vol 92 (1) ◽  
pp. 778-782 ◽  
Author(s):  
Huai-Hong Cai ◽  
Hui Wang ◽  
Jinhui Wang ◽  
Wei Wei ◽  
Pei-Hui Yang ◽  
...  

2020 ◽  
Vol 44 (35) ◽  
pp. 15195-15201 ◽  
Author(s):  
Haiyan Xu ◽  
Wei Chen ◽  
Weixia Zhang ◽  
Lixin Ju ◽  
Hongfei Lu

In this work, a novel purine based probe PTAHN was successfully designed and synthesized. PTAHN displayed high selectivity towards Zn2+via turn-on fluorescence. What's more, PTAHN can be proficiently employed for imaging Zn2+ in living cells.


Author(s):  
Aron Hakonen ◽  
Niklas Strömberg

Drinking water contamination of lead from various environmental sources, leaching consumer products and intrinsic water-pipe infrastructure is still today a matter of great concern. Therefore, new highly sensitive and convenient Pb2+ measurement schemes are necessary, especially for in-situ measurements at a low-cost. Within this work dye/ionophore/Pb2+ co-extraction and effective water phase de-colorization was utilized for highly sensitive lead measurements and sub-ppb naked-eye detection. Low-cost ionophore Benzo-18-Crown-6-ether was used, and a simple test-tube mix, shake and separate procedure was developed. Instrumental detection limits were in the low ppt region (LOD=3, LOQ=10), and naked-eye detection was 500 ppt. Note, however, that this sensing scheme still has improvement potential as concentrations of fluorophore and ionophore were not optimized. Artificial tap-water samples, leached by a standardized method, demonstrated drinking water application. Implications for this method are convenient in-situ lead ion measurements.


Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3385
Author(s):  
Wenting Zhang ◽  
Chunwei Yu ◽  
Mei Yang ◽  
Shaobai Wen ◽  
Jun Zhang

A small organic molecule P was synthesized and characterized as a fluorometric and colorimetric dual-modal probe for Hg2+. The sensing characteristics of the proposed probe for Hg2+ were studied in detail. A fluorescent enhancing property at 583 nm (>30 fold) accompanied with a visible colorimetric change, from colorless to pink, was observed with the addition of Hg2+ to P in an ethanol-water solution (8:2, v/v, 20 mM HEPES, pH 7.0), which would be helpful to fabricate Hg2+-selective probes with “naked-eye” and fluorescent detection. Meanwhile, cellular experimental results demonstrated its low cytotoxicity and good biocompatibility, and the application of P for imaging of Hg2+ in living cells was satisfactory.


Chemosensors ◽  
2018 ◽  
Vol 6 (4) ◽  
pp. 51 ◽  
Author(s):  
Aron Hakonen ◽  
Niklas Strömberg

Drinking water contamination of lead from various environmental sources, leaching consumer products, and intrinsic water-pipe infrastructure is still today a matter of great concern. Therefore, new highly sensitive and convenient Pb2+ measurement schemes are necessary, especially for in-situ measurements at a low cost. Within this work dye/ionophore/Pb2+ co-extraction and effective water phase de-colorization was utilized for highly sensitive lead measurements and sub-ppb naked-eye detection. A low-cost ionophore Benzo-18-Crown-6-ether was used, and a simple test-tube mix and separate procedure was developed. Instrumental detection limits were in the low ppt region (LOD = 3, LOQ = 10), and naked-eye detection was 500 ppt. Note, however, that this sensing scheme still has improvement potential as concentrations of fluorophore and ionophore were not optimized. Artificial tap-water samples, leached by a standardized method, demonstrated drinking water application. Implications for this method are convenient in-situ lead ion measurements.


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