From functional structure to packaging: full-printing fabrication of a microfluidic chip

Lab on a Chip ◽  
2018 ◽  
Vol 18 (13) ◽  
pp. 1859-1866 ◽  
Author(s):  
Fengyi Zheng ◽  
Zhihua Pu ◽  
Enqi He ◽  
Jiasheng Huang ◽  
Bocheng Yu ◽  
...  
Keyword(s):  
Microfluidic Chip ◽  
Microfluidic Devices ◽  
Functional Structure

This paper presents a concept of a full-printing methodology aiming at convenient and fast fabrication of microfluidic devices.

Fabrication of composite microfluidic devices for local control of oxygen tension in cell cultures

Lab on a Chip ◽  
2019 ◽  
Vol 19 (2) ◽  
pp. 306-315 ◽  
Author(s):  
Yandong Gao ◽  
Gulnaz Stybayeva ◽  
Alexander Revzin
Keyword(s):  
Oxygen Tension ◽  
Cell Cultures ◽  
Local Control ◽  
Microfluidic Chip ◽  
Gas Permeability ◽  
Microfluidic Devices

We developed a microfabrication strategy that integrated two materials with different gas permeability in a single microfluidic chip to enable local control of oxygen tension for cell cultures.

Experimental and Numerical Investigation of Two-Phase Patterns in a Cross-Junction Microfluidic Chip

2010 ◽  
Author(s):  
Aritra Sur ◽  
Lixin Yang ◽  
Dong Liu
Keyword(s):  
Pattern Formation ◽  
Flow Pattern ◽  
Microfluidic Chip ◽  
Two Phase Flow ◽  
Microfluidic Devices ◽  
Flow Patterns ◽  
Phase Flow ◽  
Two Phase ◽  
Viscous Shear ◽  
Wide Range

Two-phase microfluidic systems have been found in a wide range of engineering applications. Accurate determination of the two-phase flow patterns in microchannels is crucial to selecting appropriate predictive tools for pressure drop, heat and mass transfer in the microfluidic devices. Most of the prevailing two-phase flow maps developed using visualization techniques are unable to reveal the fundamental mechanisms responsible for the formation of specific flow pattern under given flow conditions. In this work, the high-speed photographic method is employed to study the liquid-gas two-phase flow in a cross-junction microfluidic chip with a rectangular cross section of 300 μm by 100 μm. The dynamics of bubbly, slug and annular flows are investigated. Numerical models using the VOF approach are developed to simulate the two-phase mixing and flow pattern formation in the microfluidic device. The roles of the inertia, viscous shear and surface tension forces in forming various two-phase flow patterns are discussed. The experimental results and the simulation data together provide a comprehensive phenomenological description of the key parameters and processes that govern the two-phase flow pattern formation in microfluidic devices.

scholarly journals Applications of Gelatin Methacryloyl (GelMA) Hydrogels in Microfluidic Technique-Assisted Tissue Engineering

Molecules ◽  
2020 ◽  
Vol 25 (22) ◽  
pp. 5305
Author(s):  
Taotao Liu ◽  
Wenxian Weng ◽  
Yuzhuo Zhang ◽  
Xiaoting Sun ◽  
Huazhe Yang
Keyword(s):  
Tissue Engineering ◽  
Microfluidic Chip ◽  
Production Line ◽  
Large Scale ◽  
Raw Materials ◽  
Microfluidic Devices ◽  
Building Blocks ◽  
Large Scale Integration ◽  
Scale Integration ◽  
Microfluidic Technique

In recent years, the microfluidic technique has been widely used in the field of tissue engineering. Possessing the advantages of large-scale integration and flexible manipulation, microfluidic devices may serve as the production line of building blocks and the microenvironment simulator in tissue engineering. Additionally, in microfluidic technique-assisted tissue engineering, various biomaterials are desired to fabricate the tissue mimicking or repairing structures (i.e., particles, fibers, and scaffolds). Among the materials, gelatin methacrylate (GelMA)-based hydrogels have shown great potential due to their biocompatibility and mechanical tenability. In this work, applications of GelMA hydrogels in microfluidic technique-assisted tissue engineering are reviewed mainly from two viewpoints: Serving as raw materials for microfluidic fabrication of building blocks in tissue engineering and the simulation units in microfluidic chip-based microenvironment-mimicking devices. In addition, challenges and outlooks of the exploration of GelMA hydrogels in tissue engineering applications are proposed.

Micro Milling for Polymer Materials Used in Prototyping of Microfluidic Chip Application

2012 ◽  
Vol 565 ◽  
pp. 552-557 ◽  
Author(s):  
Aramcharoen Ampara ◽  
Kah Chuan Sean Shaw ◽  
Kui Liu
Keyword(s):  
Aspect Ratio ◽  
Microfluidic Chip ◽  
Microfluidic Devices ◽  
Milling Process ◽  
Polymer Materials ◽  
Micro Milling ◽  
Machined Surface ◽  
Biocompatible Polymer ◽  
Machined Surface Quality ◽  
Materials Used

Micro milling is one of the processes that can be used in microfluidic devices fabrication. It has shown the capability for producing the freeform geometries, cost and time effectively. This paper presents the cutting strategies for micro milling process for an application of microfluidic device. The proposed strategies demonstrated the capability of micro milling process to fabricate microchannel and micropillar array from biocompatible polymer materials with good machined surface quality and high aspect ratio of up to three.

Review of Microfluidic Devices for On-Chip Chemical Sensing

2016 ◽  
Vol 136 (6) ◽  
pp. 244-249
Author(s):  
Takahiro Watanabe ◽  
Fumihiro Sassa ◽  
Yoshitaka Yoshizumi ◽  
Hiroaki Suzuki
Keyword(s):  
Chemical Sensing ◽  
Microfluidic Devices ◽  
On Chip

ДОМИНАНТНО-ФУНКЦИОНАЛЬНАЯ СТРУКТУРА ИДИОСТИЛЯ М.Ф. ДОРОНОВИЧА// Humanitarian and Socio-Economic Sciences Journal/ OEAPS Inc., Berlin, Germany, pp.46-55

2018 ◽  
Author(s):  
Olga Dorofeeva ◽  
Любовь Викторовна Чернова
Keyword(s):  
Functional Structure ◽  
The Core ◽  
Definition Of

Обращаясь к рассмотрению вопроса о доминантно-функциональной структуреидиостиля, авторы раскрывают дефиницию «идиостиль» в его связи с экстра- и интралингвистическими факторами. Рассматривая творчество публициста М.Ф. Дороновича через призму одножанровых текстов, авторы выделяют доминанты, составляющие ядро идиостиля публициста. К числу таковых относятся оценочная метафоричность, гиперболичность, фразеологичность, реализующиеся как на уровне тропов, так и на уровне синтаксических фигур.Addressing the issue of dominant-functional structure of idiostyle, the authors reveal the definition of "idiostyle" in its connection with extra- and intralinguistic factors. Considering the creativity of the writer M.F. Doronovich through the lens of various genres of texts, the authors identify the dominant components of the core of the idiostyle of the writer. These include evaluative metaphoricity, hyperbolicity, phraseology, which are implemented both at the level of tropes and at the level of syntactic figures.СВЕДЕНИЯ О ГРАНТАХ И ФИНАНСИРОВАНИИИсследование подготовлено при поддержке Российского фонда фундаментальных исследований (отделение гуманитарных и общественных наук) и Министерства образования, науки и молодёжной политики Краснодарского края в рамках научного проекта № 18-412-230008 а(р) «Язык и стиль публикаций М.Ф. Дороновича в кубанских дореволюционных газетах». Руководитель проекта – О.А. Дорофеева.

DEVELOPMENT OF COMPUTERIZED MONITORING AND CONTROL SYSTEM OF THE MOBILE ROBOT’S POSITIONING ON LARGE FERROMAGNETIC SURFACES BASED ON INTELLIGENT TECHNIQUES. AUTOMATION OF THE MONITORING AND CONTROL PROCESSES OF MOBILE ROBOT FOR PROCESSING OF LARGE INCLINED SURFACES

2019 ◽  
pp. 41-48
Author(s):  
Yan Guojun ◽  
Oleksiy Kozlov ◽  
Oleksandr Gerasin ◽  
Galyna Kondratenko
Keyword(s):  
Control System ◽  
Mobile Robot ◽  
Functional Structure ◽  
Monitoring And Control ◽  
Technological Parameters ◽  
Monitoring And Control System ◽  
Inclined Surfaces ◽  
Computerized Monitoring ◽  
And Control ◽  
Tracked Mobile Robot

The article renders the special features of the design of a tracked mobile robot (MR) for moving over inclined ferromagnetic surfaces while performing specified technological operations. There is conducted a synthesis of the functional structure and selective technological parameters (such as control coordinates) of the computerized monitoring and control system (CMCS) intended for use with this MR. Application of the CMCS with the proposed functional structure allows substantially increasing the accuracy of the MR monitoring and control, which in turn provides for a considerable enhancement in the quality and economic efficiency of the operations on processing of large ferromagnetic surfaces.

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