Metallomicelle catalyzed aerobic tandem desilylation/Glaser reaction in water

2019 ◽  
Vol 21 (11) ◽  
pp. 2899-2904 ◽  
Author(s):  
Shanyu Tang ◽  
Longjia Li ◽  
Xuanhe Ren ◽  
Jiao Li ◽  
Guanyu Yang ◽  
...  
Keyword(s):  
Copper Complexes ◽  
Nitrogen Ligands ◽  
Reaction In Water ◽  
Glaser Coupling

The copper complexes of PEG-grafted nitrogen ligands serve as metallomicellar nanoreactors for the aerobic tandem desilylation/Glaser coupling of TMS-protected alkynes in water.

Efficient and environmentally friendly Glaser coupling of terminal alkynes catalyzed by multinuclear copper complexes under base-free conditions

RSC Advances ◽  
2016 ◽  
Vol 6 (34) ◽  
pp. 28653-28657 ◽  
Author(s):  
Ling-Juan Zhang ◽  
Yan-Hong Wang ◽  
Jie Liu ◽  
Mei-Chen Xu ◽  
Xian-Ming Zhang
Keyword(s):  
Catalytic System ◽  
Room Temperature ◽  
Copper Complexes ◽  
Coupling Reaction ◽  
Environmentally Friendly ◽  
Terminal Alkynes ◽  
Free Condition ◽  
Glaser Coupling

An efficient catalytic system with multinuclear copper complexes as catalysts has been developed for the aerobic Glaser coupling reaction, which adopts environmentally friendly water as the solvent at room temperature under base-free condition.

On the interaction of copper with tris(hydroxymethyl)aminomethane

1987 ◽  
Vol 65 (4) ◽  
pp. 821-826 ◽  
Author(s):  
M. F. Colombo ◽  
L. Austrilino ◽  
O. R. Nascimento ◽  
E. E. Castellano ◽  
M. Tabak
Keyword(s):  
Room Temperature ◽  
Copper Complexes ◽  
Spectroscopic Techniques ◽  
Fold Axis ◽  
X Ray ◽  
Nitrogen Ligands ◽  
Superhyperfine Structure ◽  
Pyramid Structure ◽  
Cell Dimensions ◽  
Ray Methods

The interaction of copper with tris(hydroxymethyl)aminomethane (TRIS) has been studied by optical and esr spectroscopic techniques. In solution, three different copper complexes are obtained as a function of pH. At pH 10 the room temperature esr parameters are g0 = 2.135, A0 = 82 G and nitrogen superhyperfine structure AN = 9.5 G, characteristic of two nitrogen ligands; at pH 6.5, g0 = 2.147, A0 = 65 G and at pH 5.0, g0 = 2.180, A0 = 44 G. The high pH complex was crystallized and its molecular structure determined by X-ray methods. Space group and cell dimensions are C2/c, a = 12.955(2) Å, b = 10.793(1) Å, c = 10.091(2) Å, β = 116.62(1)°, V = 1261.4(6) Å3, Z = 4, Dc = 1.694 g cm−3, R = 0.034 for938 reflections with I > 3σ(I). The Cu2+ ion is located on the two-fold axis and coordinated to the oxygen and nitrogen atoms of two TRIS moieties; these ligand atoms form the rectangular base of a pyramid structure in which oxygen from a water molecule acts as the fifth ligand.

scholarly journals Copper Complexes of Anionic Nitrogen Ligands in the Amidation and Imidation of Aryl Halides

2008 ◽  
Vol 130 (30) ◽  
pp. 9971-9983 ◽  
Author(s):  
Jesse W. Tye ◽  
Zhiqiang Weng ◽  
Adam M. Johns ◽  
Christopher D. Incarvito ◽  
John F. Hartwig
Keyword(s):  
Copper Complexes ◽  
Aryl Halides ◽  
Nitrogen Ligands

Steric hindrance influence of a diazo link upon mesogenic properties of some ligands and related copper complexes

1997 ◽  
Vol 94 ◽  
pp. 1695-1714 ◽  
Author(s):  
P Lesot ◽  
F Perez ◽  
P Judeinstein ◽  
JP Bayle ◽  
H Allouchi ◽  
...  
Keyword(s):  
Steric Hindrance ◽  
Copper Complexes

Synthesis, characterization and biological activities of 1,3,4-oxadiazole derivatives of nalidixic acid and their copper complexes

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Nalidixic Acid ◽  
Copper Complexes ◽  
Biological Activities ◽  
Bidentate Coordination ◽  
Antibacterial And Antifungal Activities ◽  
Elemental Analyses ◽  
Oxadiazole Derivatives ◽  
Antibacterial And Antifungal ◽  
Derivatives Of ◽  
Substituted 1

A series of novel 1, 3, 4-oxadiazole analogues was synthesized from cyclization of hydrazones of substituted 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carbohydrazides were prepared from nalidixic acid. The structures of synthesized oxadiazole derivatives and their copper complexes were elucidated on the basis of FTIR, elemental analyses, 1H-NMR and atomic absorption spectral analysis. It was observed from spectral data that metal ligand ratio was 1:1 in all copper complexes and they were bidentate, coordination was found to be done through oxygen of 4-oxo group and nitrogen of oxadiazole ring. The synthesized compounds were further evaluated with biological activities and compared with parent hydrazones. Copper complexes possess antibacterial and antifungal activities better than the oxadiazoles while they have better antioxidant activity then copper complexes. Parent hydrazones were better in all biological activities than synthesized oxadiazoles.

Complexes of Cu (II) with a-Ketoglutaric Acid and 1- (o-tolyl) Biguanide Synthesis, characterization and biological Activity

2019 ◽  
Vol 70 (10) ◽  
pp. 3603-3610
Author(s):  
Madalina Mihalache ◽  
Cornelia Guran ◽  
Aurelia Meghea ◽  
Vasile Bercu ◽  
Ludmila Motelica ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Biological Activity ◽  
Candida Albicans ◽  
Antifungal Activity ◽  
Copper Complexes ◽  
Substrate Adhesion ◽  
Inert Substrate

The three copper complexes having a-ketoglutaric acid (H2A) and 1- (o-tolyl) biguanide (TB) ligands have been synthesized and characterized. The proposed formulas for these complexes are: [Cu(TB)(HA)]Cl (C1), [Cu(TB)(HA)CH3COO]�H2O (C2) and [Cu(TB)(HA)](NO3) (C3) where HA represents deprotonated H2A. The complexes obtained were tested for antibacterial activity against Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 27853, antifungal activity on Candida albicans ATCC 10231 and antitumor activity on HeLa tumor cells. Due to the antitumor, antifungal, antimicrobial activity and inhibition of inert substrate adhesion, complexes synthesized could be used for potential therapeutic applications.

Sign in / Sign up

Export Citation Format

Share Document