In vitro effect of green tea and turmeric extracts on GLP-1 and CCK secretion: the effect of gastrointestinal digestion

2018 ◽  
Vol 9 (10) ◽  
pp. 5245-5250 ◽  
Author(s):  
David Planes-Muñoz ◽  
Rubén López-Nicolás ◽  
Carlos A. González-Bermúdez ◽  
Gaspar Ros-Berruezo ◽  
Carmen Frontela-Saseta
Keyword(s):  
Green Tea ◽  
Plant Extract ◽  
Gastrointestinal Digestion ◽  
Digestion Process ◽  
Vitro Effect

Plant extract activity can be modified by the digestion process.

In Vitro Effect of Ankaferd Blood Stopper®, a Plant Extract Against Mycobacterium tuberculosis Isolates

2013 ◽  
pp. 71-78 ◽  
Author(s):  
Aydın DEVECİ ◽  
Ahmet Yılmaz ÇOBAN ◽  
Yeliz TANRIVERDİ ÇAYCI ◽  
Özlem ACİCBE ◽  
Nuriye TAŞDELEN FIŞGIN ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Plant Extract ◽  
Ankaferd Blood Stopper ◽  
Vitro Effect

scholarly journals Stability and Fermentability of Green Tea Flavonols in In-Vitro-Simulated Gastrointestinal Digestion and Human Fecal Fermentation

2019 ◽  
Vol 20 (23) ◽  
pp. 5890 ◽  
Author(s):  
Chan-Su Rha ◽  
Hyunbin Seong ◽  
Young Sung Jung ◽  
Davin Jang ◽  
Jun-Gu Kwak ◽  
...  
Keyword(s):  
Green Tea ◽  
Digestive System ◽  
Limited Information ◽  
Gastrointestinal Digestion ◽  
Simulated Gastrointestinal Digestion ◽  
Simulated Digestion ◽  
Intestinal Fluids ◽  
Derivatives Of ◽  
Acetate Butyrate

Flavonols, the second most abundant flavonoids in green tea, exist mainly in the form of glycosides. Flavonols are known to have a variety of beneficial health effects; however, limited information is available on their fate in the digestive system. We investigated the digestive stability of flavonol aglycones and glycosides from green tea under simulated digestion and anaerobic human fecal fermentation. Green tea fractions rich in flavonol glycosides and aglycones, termed flavonol-glycoside-rich fraction (FLG) and flavonol-aglycone-rich fraction (FLA) hereafter, were obtained after treatment with cellulase and tannase, respectively. Kaempferol and its glycosides were found to be more stable in simulated gastric and intestinal fluids than the derivatives of quercetin and myricetin. Anaerobic human fecal fermentation with FLG and FLA increased the populations of Lactobacilli spp. and Bifidobacteria spp. and generated various organic acids, such as acetate, butyrate, propionate, and lactate, among which butyrate was produced in the highest amount. Our findings indicate that some stable polyphenols have higher bioaccessibilities in the gastrointestinal tract and that their health-modulating effects result from their interactions with microbes in the gut.

scholarly journals In vitro effect of pine bark extract added to fruit juices on gutinflammation after gastrointestinal digestion

2013 ◽  
Vol 72 (OCE1) ◽  
Author(s):  
C. Frontela-Saseta ◽  
R. López-Nicolás ◽  
C. A. González-Bermúdez ◽  
P. Peso-Echarri ◽  
L. Fernández-Palacios ◽  
...  
Keyword(s):  
Fruit Juices ◽  
Pine Bark ◽  
Bark Extract ◽  
Gastrointestinal Digestion ◽  
Vitro Effect

scholarly journals Changes in the Organosulfur and Polyphenol Compound Profiles of Black and Fresh Onion during Simulated Gastrointestinal Digestion

Foods ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 337
Author(s):  
Alicia Moreno-Ortega ◽  
José Luis Ordóñez ◽  
Rafael Moreno-Rojas ◽  
José Manuel Moreno-Rojas ◽  
Gema Pereira-Caro
Keyword(s):  
High Performance ◽  
High Resolution Mass Spectrometry ◽  
Methionine Sulfoxide ◽  
Organosulfur Compounds ◽  
Gastrointestinal Digestion ◽  
Digestion Process ◽  
Simulated Gastrointestinal Digestion ◽  
Positive Effect ◽  
Cysteine Sulfoxide

This study aims to determine the changes in, and bioaccessibility of, polyphenols and organosulfur compounds (OSCs) during the simulated gastrointestinal digestion of black onion, a novel product derived from fresh onion by a combination of heat and humidity treatment, and to compare it with its fresh counterpart. Fresh and black onions were subjected to in-vitro gastrointestinal digestion, and their polyphenol and OSC profiles were determined by ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry (UHPLC-HRMS). Although to a lesser extent than in the fresh onion, the phenolic compounds in the black variety remained stable during the digestion process, presenting a higher bioaccessibility index (BI) with recovery corresponding to 41.1%, compared with that of fresh onion (23.5%). As for OSCs, apart from being more stable after the digestion process, with a BI of 83%, significantly higher quantities (21 times higher) were found in black onion than in fresh onion, suggesting that the black onion production process has a positive effect on the OSC content. Gallic acid, quercetin, isorhamnetin, and ɣ-glutamyl-S-(1-propenyl)-L-cysteine sulfoxide were the most bioaccessible compounds in fresh onion, while isorhamnetin, quercetin-diglucoside, ɣ-glutamyl-S-methyl-L-cysteine sulfoxide and methionine sulfoxide were found in black onion. These results indicate that OSCs and polyphenols are more bioaccessible in black onion than in fresh onion, indicating a positive effect of the processing treatment.

Modulation of gastrointestinal digestion of β-lactoglobulin and micellar casein following binding by (−)-epigallocatechin-3-gallate (EGCG) and green tea flavanols

2020 ◽  
Vol 11 (7) ◽  
pp. 6038-6053
Author(s):  
Özge Dönmez ◽  
Burçe Ataç Mogol ◽  
Vural Gökmen ◽  
Ning Tang ◽  
Mogens Larsen Andersen ◽  
...  
Keyword(s):  
Free Radical ◽  
Green Tea ◽  
Radical Scavenging ◽  
Milk Proteins ◽  
Free Radical Scavenging ◽  
Gastrointestinal Digestion ◽  
Micellar Casein ◽  
Tea Extract ◽  
Β Lactoglobulin

Milk proteins bind flavanoids (EGCG and green tea extract), affecting their in vitro digestibility and modulating flavanoid free radical scavenging.

scholarly journals Molecular Rescue of Dyrk1A Overexpression Alterations in Mice with Fontup® Dietary Supplement: Role of Green Tea Catechins

2020 ◽  
Vol 21 (4) ◽  
pp. 1404 ◽  
Author(s):  
Yuchen Gu ◽  
Gautier Moroy ◽  
Jean-Louis Paul ◽  
Anne-Sophie Rebillat ◽  
Mara Dierssen ◽  
...  
Keyword(s):  
Green Tea ◽  
Epigallocatechin Gallate ◽  
Nutritional Supplement ◽  
Green Tea Extract ◽  
Epicatechin Gallate ◽  
Tea Catechins ◽  
Green Tea Catechins ◽  
Tea Extract ◽  
Vitro Effect

Epigallocatechin gallate (EGCG) is an inhibitor of DYRK1A, a serine/threonine kinase considered to be a major contributor of cognitive dysfunctions in Down syndrome (DS). Two clinical trials in adult patients with DS have shown the safety and efficacy to improve cognitive phenotypes using commercial green tea extract containing EGCG (45% content). In the present study, we performed a preclinical study using FontUp®, a new nutritional supplement with a chocolate taste specifically formulated for the nutritional needs of patients with DS and enriched with a standardized amount of EGCG in young mice overexpressing Dyrk1A (TgBACDyrk1A). This preparation is differential with previous one used, because its green tea extract has been purified to up 94% EGCG of total catechins. We analyzed the in vitro effect of green tea catechins not only for EGCG, but for others residually contained in FontUp®, on DYRK1A kinase activity. Like EGCG, epicatechin gallate was a noncompetitive inhibitor against ATP, molecular docking computations confirming these results. Oral FontUp® normalized brain and plasma biomarkers deregulated in TgBACDyrk1A, without negative effect on liver and cardiac functions. We compared the bioavailability of EGCG in plasma and brain of mice and have demonstrated that EGCG had well crossed the blood-brain barrier.

Biosorption of biocompounds from white and green tea in Saccharomyces cerevisiae waste: Study of the secondary metabolites by UPLC-QToF-MS and simulated in vitro gastrointestinal digestion

2021 ◽  
Vol 41 ◽  
pp. 101001
Author(s):  
Valéria Rampazzo Ribeiro ◽  
Giselle Maria Maciel ◽  
Mariana Millan Fachi ◽  
Roberto Pontarolo ◽  
Isabela de Andrade Arruda Fernandes ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Secondary Metabolites ◽  
Green Tea ◽  
Gastrointestinal Digestion ◽  
In Vitro Gastrointestinal Digestion

In vitro effect of an aqueous extract of Artocarpus lakoocha on the intestinal parasites in cattle

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
N Saowakon ◽  
P Chaichanasak ◽  
C Wanichanon ◽  
V Reutrakul ◽  
P Sobhon
Keyword(s):  
Aqueous Extract ◽  
Intestinal Parasites ◽  
Vitro Effect
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