Facile preparation of phospholipid–amorphous calcium carbonate hybrid nanoparticles: toward controllable burst drug release and enhanced tumor penetration

2018 ◽  
Vol 54 (93) ◽  
pp. 13080-13083 ◽  
Author(s):  
Cheng Wang ◽  
Xuerong Liu ◽  
Shaoqing Chen ◽  
Fuqiang Hu ◽  
Jihong Sun ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Drug Release ◽  
Hybrid System ◽  
Hybrid Nanoparticles ◽  
Drug Penetration ◽  
Amorphous Calcium Carbonate ◽  
Tumor Penetration ◽  
Tumor Tissues ◽  
Facile Preparation

A hybrid system able to specifically realize water-responsive burst drug release and potentiate drug penetration into deep tumor tissues has been developed.

scholarly journals Correction: Facile preparation of phospholipid–amorphous calcium carbonate hybrid nanoparticles: toward controllable burst drug release and enhanced tumor penetration

2020 ◽  
Vol 56 (73) ◽  
pp. 10768-10769
Author(s):  
Cheng Wang ◽  
Xuerong Liu ◽  
Shaoqing Chen ◽  
Fuqiang Hu ◽  
Jihong Sun ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Drug Release ◽  
Hybrid Nanoparticles ◽  
Amorphous Calcium Carbonate ◽  
Tumor Penetration ◽  
Facile Preparation

Correction for ‘Facile preparation of phospholipid–amorphous calcium carbonate hybrid nanoparticles: toward controllable burst drug release and enhanced tumor penetration’ by Cheng Wang et al., Chem. Commun., 2018, 54, 13080–13083, DOI: 10.1039/C8CC07694D.

Deep Drug Penetration of Nanodrug Aggregates at Tumor Tissues by Fast Extracellular Drug Release

2020 ◽  
pp. 2001430
Author(s):  
Yongchao Yao ◽  
Xin Dai ◽  
Yifeng Tan ◽  
Ying Chen ◽  
Chunyan Liao ◽  
...  
Keyword(s):  
Drug Release ◽  
Drug Penetration ◽  
Tumor Tissues

scholarly journals Correction: Taking advantage of the disadvantage: employing the high aqueous instability of amorphous calcium carbonate to realize burst drug release within cancer cells

2020 ◽  
Vol 8 (33) ◽  
pp. 7558-7558
Author(s):  
Cheng Wang ◽  
Shaoqing Chen ◽  
Qin Yu ◽  
Fuqiang Hu ◽  
Hong Yuan
Keyword(s):  
Calcium Carbonate ◽  
Drug Release ◽  
Cancer Cells ◽  
Amorphous Calcium Carbonate

Correction for ‘Taking advantage of the disadvantage: employing the high aqueous instability of amorphous calcium carbonate to realize burst drug release within cancer cells’ by Cheng Wang et al., J. Mater. Chem. B, 2017, 5, 2068–2073, DOI: 10.1039/C6TB02826H.

Taking advantage of the disadvantage: employing the high aqueous instability of amorphous calcium carbonate to realize burst drug release within cancer cells

2017 ◽  
Vol 5 (11) ◽  
pp. 2068-2073 ◽  
Author(s):  
Cheng Wang ◽  
Shaoqing Chen ◽  
Qin Yu ◽  
Fuqiang Hu ◽  
Hong Yuan
Keyword(s):  
Calcium Carbonate ◽  
Drug Release ◽  
Cancer Cells ◽  
Major Obstacle ◽  
Burst Release ◽  
Amorphous Calcium Carbonate

The high aqueous instability of amorphous calcium carbonate (ACC), which will lead to a burst release of its payload, has generally been recognized as the major obstacle for its further application in nanomedicine.

scholarly journals Pure hydroxyapatite synthesis originating from amorphous calcium carbonate

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Michika Sawada ◽  
Kandi Sridhar ◽  
Yasuharu Kanda ◽  
Shinya Yamanaka
Keyword(s):  
Calcium Carbonate ◽  
Calcium Phosphate ◽  
Room Temperature ◽  
Molar Ratio ◽  
Final Phase ◽  
Amorphous Calcium Carbonate ◽  
Phosphate Compound ◽  
Synthesis Strategy ◽  
Phosphorylation Reaction ◽  
Subsequent Calcination

AbstractWe report a synthesis strategy for pure hydroxyapatite (HAp) using an amorphous calcium carbonate (ACC) colloid as the starting source. Room-temperature phosphorylation and subsequent calcination produce pure HAp via intermediate amorphous calcium phosphate (ACP). The pre-calcined sample undergoes a competitive transformation from ACC to ACP and crystalline calcium carbonate. The water content, ACC concentration, Ca/P molar ratio, and pH during the phosphorylation reaction play crucial roles in the final phase of the crystalline phosphate compound. Pure HAp is formed after ACP is transformed from ACC at a low concentration (1 wt%) of ACC colloid (1.71 < Ca/P < 1.88), whereas Ca/P = 1.51 leads to pure β-tricalcium phosphate. The ACP phases are precursors for calcium phosphate compounds and may determine the final crystalline phase.

scholarly journals On the Relation of Amorphous Calcium Carbonate and the Macromechanical Properties of Sea Urchin Spines

2020 ◽  
Vol 22 (4) ◽  
pp. 1900922 ◽  
Author(s):  
Christoph Lauer ◽  
Sebastian Haußmann ◽  
Patrick Schmidt ◽  
Carolin Fischer ◽  
Doreen Rapp ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Sea Urchin ◽  
Amorphous Calcium Carbonate ◽  
Sea Urchin Spines

scholarly journals Transformation mechanism of amorphous calcium carbonate into calcite in the sea urchin larval spicule

2008 ◽  
Vol 105 (45) ◽  
pp. 17362-17366 ◽  
Author(s):  
Y. Politi ◽  
R. A. Metzler ◽  
M. Abrecht ◽  
B. Gilbert ◽  
F. H. Wilt ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Sea Urchin ◽  
Amorphous Calcium Carbonate ◽  
Transformation Mechanism
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