An efficient method for the synthesis of a polymer brush via click chemistry and its ultrasensitive electrochemical detection of AFP

2018 ◽  
Vol 10 (20) ◽  
pp. 2390-2397 ◽  
Author(s):  
Dongcheng Yang ◽  
Jing Wang ◽  
Hou Chen ◽  
Hui Xu ◽  
Wenxiang Wang ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Click Chemistry ◽  
Tumor Markers ◽  
Electrochemical Detection ◽  
Efficient Method ◽  
Polymer Brush ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection

A sensitive electrochemical immunosensor based on polyacrylonitrile-g-poly(hydroxyethylmethacrylate) (PAN-g-PHEMA)/graphene oxide (GO) composites was prepared for the ultrasensitive detection of tumor markers.

Construction of electrochemical immunosensor based on redox hydrogel for ultrasensitive detection of carcinoembryonic antigen

2021 ◽  
Author(s):  
Xiangrong Huang ◽  
Na Wu ◽  
Wenxiu Liu ◽  
Yazhuo Shang ◽  
Honglai Liu ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Carcinoembryonic Antigen ◽  
Electrochemical Detection ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free

In this work, a novel redox hydrogel was proposed for ultrasensitive label-free electrochemical detection of carcinoembryonic antigen (CEA). The redox hydrogel composed by cellulose nanocrystalline (CNC), methylene blue (MB), multi-walled...

Label-free electrochemical immunosensor based on gold nanoparticle/polyethyleneimine/reduced graphene oxide nanocomposite for the ultrasensitive detection of cancer biomarker matrix metalloproteinase-1

The Analyst ◽  
2021 ◽  
Author(s):  
Xinke Liu ◽  
Lu-Yin Lin ◽  
Fu-Yen Tseng ◽  
Yu-Cheng Tan ◽  
Jian Li ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Matrix Metalloproteinase ◽  
Gold Nanoparticle ◽  
Reduced Graphene Oxide ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free ◽  
Matrix Metalloproteinase 1 ◽  
Reduced Graphene ◽  
P Matrix

Matrix metalloproteinase-1 (MMP-1) is associated with many types of cancers, including oral, colorectal, and brain cancers. This paper describes the fabrication of an MMP-1 immunosensor based on a gold nanoparticle/polyethyleneimine/reduced...

Graphene oxide-based electrochemical sensor: a platform for ultrasensitive detection of heavy metal ions

RSC Advances ◽  
2014 ◽  
Vol 4 (47) ◽  
pp. 24653-24657 ◽  
Author(s):  
Xuezhong Gong ◽  
Yunlong Bi ◽  
Yihua Zhao ◽  
Guozhen Liu ◽  
Wey Yang Teoh
Keyword(s):  
Heavy Metal ◽  
Graphene Oxide ◽  
Metal Ions ◽  
Electrochemical Sensor ◽  
Electrochemical Detection ◽  
Heavy Metal Ions ◽  
Gold Surface ◽  
Ultrasensitive Detection ◽  
Control Electrode ◽  
Graphene Oxide Sheets

Facile functionalization of graphene oxide sheets on gold surface results in complexation-enhanced electrochemical detection of heavy metal ions, shown here for Pb2+, Cu2+ and Hg2+, with improved detection limits by two orders of magnitude relative to the control electrode.

Preparation of a novel sandwich-type electrochemical immunosensor for AFP detection based on an ATRP and click chemistry technique

2020 ◽  
Vol 11 (4) ◽  
pp. 900-908 ◽  
Author(s):  
Xiaoqing Zhao ◽  
Na Wang ◽  
Hou Chen ◽  
Liangjiu Bai ◽  
Hui Xu ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Polymer Brush ◽  
Electrochemical Immunosensor ◽  
Functional Polymer ◽  
Sandwich Type ◽  
Synthesis Methodology ◽  
Application Scope

It is extremely important to explore the synthesis methodology and application scope of functional polymer brush-based nanocomposites.

scholarly journals A label-free immunosensor based on PHEMA/graphene oxide nanocomposite for simultaneous electrochemical determination of alpha fetoprotein

RSC Advances ◽  
2019 ◽  
Vol 9 (30) ◽  
pp. 17187-17193 ◽  
Author(s):  
Ying Liang ◽  
Xiaoqing Zhao ◽  
Na Wang ◽  
Jing Wang ◽  
Hou Chen ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Electrochemical Determination ◽  
Electrochemical Immunosensor ◽  
Alpha Fetoprotein ◽  
Ultrasensitive Detection ◽  
Hydroxyethyl Methacrylate ◽  
Label Free

An electrochemical immunosensor based on poly(2-hydroxyethyl methacrylate) (PHEMA)/graphene oxide (GO) nanocomposite was designed in a simple way for the ultrasensitive detection of tumor makers (alpha-fetoprotein, AFP as a model).

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