The structural and organic magnetoresistance response of poly(9-vinyl carbazole) using low applied magnetic fields and magnetic nanoparticle addition

2017 ◽  
Vol 5 (15) ◽  
pp. 3779-3787 ◽  
Author(s):  
Mariano Romero ◽  
Ricardo Faccio ◽  
Milton A. Tumelero ◽  
André A. Pasa ◽  
Alvaro W. Mombrú
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetic Fields ◽  
Magnetic Nanoparticle ◽  
Structural Modifications ◽  
Organic Magnetoresistance

Evidence of PVK singlet-to-triplet and structural modifications are revealed with the addition of magnetic nanoparticles and low applied magnetic fields.

scholarly journals Deploying clinical grade magnetic nanoparticles with magnetic fields to magnetolabel neural stem cells in adherent versus suspension cultures

RSC Advances ◽  
2015 ◽  
Vol 5 (54) ◽  
pp. 43353-43360 ◽  
Author(s):  
D. Weinberg ◽  
C. F. Adams ◽  
D. M. Chari
Keyword(s):  
Stem Cells ◽  
Magnetic Nanoparticles ◽  
Magnetic Fields ◽  
Neural Stem Cells ◽  
Magnetic Nanoparticle ◽  
Cell Tracking ◽  
Suspension Cultures ◽  
Clinical Grade ◽  
Non Invasive ◽  
Invasive Cell

This is the first demonstration that oscillating magnetic fields safely promote the uptake of a clinical-grade magnetic nanoparticle (Lumirem/Ferumoxsil) into neural stem cells for non-invasive cell tracking capabilities.

Behaviors of Bio-Functionalized Magnetic Nanoparticle Clusters in a Rotating Magnetic Field

2012 ◽  
Author(s):  
Chin-Yih Hong ◽  
Ji-Ching Lai ◽  
Chia-Chung Tang
Keyword(s):  
Magnetic Field ◽  
Aqueous Solution ◽  
Magnetic Nanoparticles ◽  
Magnetic Fields ◽  
Magnetic Nanoparticle ◽  
Critical Diameter ◽  
Rotating Magnetic Field ◽  
Magnetic Clusters ◽  
Rotating Magnetic Fields ◽  
Nanoparticle Clusters

Manipulation of magnetic nanoparticles has many applications in several fields and the behaviors of magnetic nanoparticles subjected to rotating or alternating magnetic fields attracted more attention from biomedical applications. In an aqueous solution containing bio-functionalized magnetic nanoparticles, due to the interaction between biomolecules, these nanoparticles agglomerate and form clusters with various sizes and shapes. In this study, the behaviors of magnetic nanoparticle clusters in an aqueous solution under rotating magnetic fields were investigated. Due to the interaction between the rotating magnetic field and the net magnetic dipole moment, the clusters were subjected to forced vibration. Two motion modes of clusters were observed as the magnetic field rotated. These two modes are rotation and oscillation. The diameters of the magnetic clusters with rotational or oscillational motions were measured. A critical diameter range of magnetic cluster was defined and the range is between 10.21 μm and 6.17 μm that could be used to distinguish rotation and oscillation of clusters.

scholarly journals Understanding intracellular nanoparticle trafficking fates through spatiotemporally resolved magnetic nanoparticle recovery

2021 ◽  
Author(s):  
Emily Sheridan ◽  
Silvia Vercellino ◽  
Lorenzo Cursi ◽  
Laurent Adumeau ◽  
James A. Behan ◽  
...  
Keyword(s):  
Decision Making ◽  
Magnetic Nanoparticles ◽  
Magnetic Nanoparticle ◽  
Magnetic Extraction

We describe how magnetic nanoparticles can be used to study intracellular nanoparticle trafficking, and how magnetic extraction may be integrated with downstream analyses to investigate nanoscale decision-making events.

scholarly journals Therapeutic Potential of Magnetic Nanoparticle-Based Human Adipose-Derived Stem Cells in a Mouse Model of Parkinson’s Disease

2021 ◽  
Vol 22 (2) ◽  
pp. 654
Author(s):  
Ka Young Kim ◽  
Keun-A Chang
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Parkinson's Disease ◽  
Magnetic Nanoparticles ◽  
Substantia Nigra ◽  
Mouse Model ◽  
Magnetic Nanoparticle ◽  
Imaging System ◽  
Therapeutic Potential ◽  
Adipose Derived Stem Cells

Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra. Several treatments for PD have focused on the management of physical symptoms using dopaminergic agents. However, these treatments induce various adverse effects, including hallucinations and cognitive impairment, owing to non-targeted brain delivery, while alleviating motor symptoms. Furthermore, these therapies are not considered ultimate cures owing to limited brain self-repair and regeneration abilities. In the present study, we aimed to investigate the therapeutic potential of human adipose-derived stem cells (hASCs) using magnetic nanoparticles in a 6-hydroxydopamine (6-OHDA)-induced PD mouse model. We used the Maestro imaging system and magnetic resonance imaging (MRI) for in vivo tracking after transplantation of magnetic nanoparticle-loaded hASCs to the PD mouse model. The Maestro imaging system revealed strong hASCs signals in the brains of PD model mice. In particular, MRI revealed hASCs distribution in the substantia nigra of hASCs-injected PD mice. Behavioral evaluations, including apomorphine-induced rotation and rotarod performance, were significantly recovered in hASCs-injected 6-OHDA induced PD mice when compared with saline-treated counterparts. Herein, we investigated whether hASCs transplantation using magnetic nanoparticles recovered motor functions through targeted brain distribution in a 6-OHDA induced PD mice. These results indicate that magnetic nanoparticle-based hASCs transplantation could be a potential therapeutic strategy in PD.

Simulated Clustering Dynamics of Colloidal Magnetic Nanoparticles

Nanoscale ◽  
2021 ◽  
Author(s):  
Frederik Laust Durhuus ◽  
Lau Halkier Wandall ◽  
Mathias Hoeg Boisen ◽  
Mathias Kure ◽  
Marco Beleggia ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Self Assembly ◽  
Biomedical Applications ◽  
Magnetic Nanoparticle ◽  
Bottom Up ◽  
Novel Materials ◽  
Nanoparticle Clusters ◽  
Clustering Dynamics

Magnetically guided self-assembly of nanoparticles is a promising bottom-up method to fabricate novel materials and superstructures, such as, for example, magnetic nanoparticle clusters for biomedical applications. The existence of assembled...

scholarly journals Transient cell stiffening triggered by magnetic nanoparticle exposure

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Jose E. Perez ◽  
Florian Fage ◽  
David Pereira ◽  
Ali Abou-Hassan ◽  
Sophie Asnacios ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Magnetic Nanoparticles ◽  
Magnetic Nanoparticle ◽  
Early Time ◽  
Population Level ◽  
Short Time Scale ◽  
Initial Contact ◽  
Almost All ◽  
The Impact ◽  
Stiffening Effect

Abstract Background The interactions between nanoparticles and the biological environment have long been studied, with toxicological assays being the most common experimental route. In parallel, recent growing evidence has brought into light the important role that cell mechanics play in numerous cell biological processes. However, despite the prevalence of nanotechnology applications in biology, and in particular the increased use of magnetic nanoparticles for cell therapy and imaging, the impact of nanoparticles on the cells’ mechanical properties remains poorly understood. Results Here, we used a parallel plate rheometer to measure the impact of magnetic nanoparticles on the viscoelastic modulus G*(f) of individual cells. We show how the active uptake of nanoparticles translates into cell stiffening in a short time scale (< 30 min), at the single cell level. The cell stiffening effect is however less marked at the cell population level, when the cells are pre-labeled under a longer incubation time (2 h) with nanoparticles. 24 h later, the stiffening effect is no more present. Imaging of the nanoparticle uptake reveals almost immediate (within minutes) nanoparticle aggregation at the cell membrane, triggering early endocytosis, whereas nanoparticles are almost all confined in late or lysosomal endosomes after 2 h of uptake. Remarkably, this correlates well with the imaging of the actin cytoskeleton, with actin bundling being highly prevalent at early time points into the exposure to the nanoparticles, an effect that renormalizes after longer periods. Conclusions Overall, this work evidences that magnetic nanoparticle internalization, coupled to cytoskeleton remodeling, contributes to a change in the cell mechanical properties within minutes of their initial contact, leading to an increase in cell rigidity. This effect appears to be transient, reduced after hours and disappearing 24 h after the internalization has taken place.

Magnetic Nanoparticle Arrays with Ultra-Uniform Length Electrodeposited in Highly Ordered Alumina Nanopores(“Alumite”)

2000 ◽  
Vol 636 ◽  
Author(s):  
Robert M. Metzger ◽  
Ming Sun ◽  
Giovanni Zangari ◽  
Mohammad Shamsuzzoha
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetic Nanoparticle ◽  
Great Promise ◽  
Nanometer Scale ◽  
Nanoparticle Arrays ◽  
Low Aspect Ratio ◽  
Ordered Arrays ◽  
High Uniformity ◽  
Pulse Reverse ◽  
Hexagonally Ordered

AbstractWe report nanometer-scale ordered arrays of cylindrical magnetic nanoparticles with low aspect ratio and ultra-high uniformity. Protracted anodization provides hexagonally ordered nanopores in amorphous Al2O3. For instance, pulsed electrochemical deposition grows Co particles of uniform length from the bottoms of these pores: these particles are polycrystalline and randomly oriented. The magnetism of the array is dominated by particle shape and by inter-particle magnetostatic interactions. A very clear transition of the anisotropy from perpendicular to in-plane is observed at a height to radius ratio of about 2. This pulse-reverse electrodeposition shows great promise for a reliable synthesis of uniform nanostructures of many metals.

Thermal Conductivity Enhancement of Room Temperature Ionic Liquids (RTILs) With Various Magnetic Nanoparticles

2012 ◽  
Author(s):  
N. Y. Jagath B. Nikapitiya ◽  
Hyejin Moon
Keyword(s):  
Thermal Conductivity ◽  
Ionic Liquids ◽  
Magnetic Nanoparticles ◽  
Magnetic Fields ◽  
Room Temperature ◽  
Particle Concentration ◽  
Thermal Conductivity Enhancement ◽  
Room Temperature Ionic Liquids ◽  
Conductivity Enhancement ◽  
Magnetic Nanofluids

This paper reports an experimental study of thermal conductivity of room temperature ionic liquids (RTILs) based magnetic nanofluids. Various magnetic nanoparticles of metal oxides with high thermal conductivity, such as CuO, Al2O3, Fe3O4 and Carbon Nano Tubes (CNTs), were used to prepare magnetic nanofluids, while RTIL, trihexyl (tetradecyl) posphonium dicyanamide was used as the base fluid. Two major parameters that affect to the thermal conductivity enhancement of fluids were investigated. The effect of particle concentration and external magnetic fields were tested. It was observed that the magnetic nanofluids thermal conductivities increase with increment of particle concentration and external magnetic field parallel to the temperature gradient. Besides, it was observed that under higher magnetic fields, thermal conductivity enhancement tends to approach a saturation state. Surfactant was used to disperse magnetic nanoparticles within the RTILs. The transient hot wire method was used for this investigation.

scholarly journals Magnetic nanoparticle-conjugated polymeric micelles for combined hyperthermia and chemotherapy

Nanoscale ◽  
2015 ◽  
Vol 7 (39) ◽  
pp. 16470-16480 ◽  
Author(s):  
Hyun-Chul Kim ◽  
Eunjoo Kim ◽  
Sang Won Jeong ◽  
Tae-Lin Ha ◽  
Sang-Im Park ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Synergistic Effect ◽  
Cancer Cells ◽  
Anticancer Drug ◽  
Magnetic Nanoparticle ◽  
Polymeric Micelles ◽  
Alternating Magnetic Field ◽  
Rapid Release

The cytotoxicity of magnetic nanoparticles-conjugated polymeric micelles encapsulated with an anticancer drug on cancer cells was enhanced by the synergistic effect of heat and the rapid release of the drug under an alternating magnetic field.

Magnetic nanoparticles for the measurement of cell mechanics using force-induced remnant magnetization spectroscopy

Nanoscale ◽  
2020 ◽  
Vol 12 (27) ◽  
pp. 14573-14580
Author(s):  
Min Xu ◽  
Xueyan Feng ◽  
Feng Feng ◽  
Hantao Pei ◽  
Ruping Liu ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cell Mechanics ◽  
Magnetic Nanoparticle ◽  
Adhesion Force ◽  
Force Spectroscopy ◽  
Remnant Magnetization ◽  
A Cell ◽  
Novel Method

Interactions of magnetic nanoparticles with cells were investigated from a cell mechanics perspective, and magnetic nanoparticle-based force spectroscopy was developed as a novel method to measure the adhesion force among various cancer cell lines.

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