Interconnected macroporous 3D scaffolds templated from gelatin nanoparticle-stabilized high internal phase emulsions for biomedical applications

Soft Matter ◽  
2017 ◽  
Vol 13 (21) ◽  
pp. 3871-3878 ◽  
Author(s):  
Huan Tan ◽  
Jingjing Wei ◽  
Guanqing Sun ◽  
Changdao Mu ◽  
Wei Lin ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
3D Scaffolds ◽  
Internal Phase

scholarly journals 3D Scaffolds Based on Conductive Polymers for Biomedical Applications

2018 ◽  
Vol 20 (1) ◽  
pp. 73-89 ◽  
Author(s):  
Nuria Alegret ◽  
Antonio Dominguez-Alfaro ◽  
David Mecerreyes
Keyword(s):  
Biomedical Applications ◽  
Conductive Polymers ◽  
3D Scaffolds

Regenerative medicine under control of 3D scaffolds: Current state and progress of tissue scaffolds

2020 ◽  
Vol 15 ◽  
Author(s):  
Ali Golchin ◽  
Sina Farzaneh ◽  
Bahareh Porjabbar ◽  
Fatemeh Sadegian ◽  
Masoumeh Estaji ◽  
...  
Keyword(s):  
Regenerative Medicine ◽  
Cell Fate ◽  
Biomedical Applications ◽  
Three Dimensional ◽  
3D Scaffold ◽  
3D Scaffolds ◽  
Nutrient Delivery ◽  
Cell Functions ◽  
Current State ◽  
Biomaterial Scaffolds

: Currently, combining stem cells [SCs] with biomaterial scaffolds provides a promising strategy for the future of biomedicine and regenerative medicine [RG]. The cells need similar substrates of extra cellular matrix [ECM] for normal tissue development that signifies the importance of three dimensional [3D] scaffolds to determine cell fate. Herein, we present the great importance and also positive contributions of corresponding 3D scaffolds on cell functions including cell interactions, cell migrations, and nutrient delivery. Further on, the synthesis techniques which are recruited to fabricate the 3D scaffolds, are discussed besides the related studies of 3D scaffold for different tissues are reported in this paper completely. This review focuses on 3D scaffolds that have been used for tissue engineering purposes and directing stem cell fate as a means of producing replacements for biomedical applications.

scholarly journals Fast transformation of 2D nanofiber membranes into pre-molded 3D scaffolds with biomimetic and oriented porous structure for biomedical applications

2020 ◽  
Vol 7 (2) ◽  
pp. 021406 ◽  
Author(s):  
Shixuan Chen ◽  
Johnson V. John ◽  
Alec McCarthy ◽  
Mark A. Carlson ◽  
Xiaowei Li ◽  
...  
Keyword(s):  
Porous Structure ◽  
Biomedical Applications ◽  
3D Scaffolds ◽  
Nanofiber Membranes

6.2 Hybridization of Thiol–Ene Chemistry Hydrogels for Biomedical Applications

2022 ◽  
Author(s):  
Z. Xu ◽  
K. M. Bratlie
Keyword(s):  
Free Radical ◽  
Biomedical Applications ◽  
Thiol Groups ◽  
Double Bonds ◽  
3D Scaffolds ◽  
Ene Reactions

AbstractLight-triggered thiol–ene polymerization is a powerful tool for synthesizing hydrogels that are aimed to be applied in situ or used as 3D scaffolds. Thiol–ene reactions are a class of click transformations that involve free-radical-mediated addition of electron-rich thiol groups to electron-poor carbon–carbon double bonds. When tuned with homopolymerization of the carbon–carbon double bonds, the resultant hydrogel properties can be finely adjusted. In this review, commonly used methods for modifying polymers with thiol groups or double bonds are discussed, and strategies to overcome flaws in thiol–ene hydrogels are provided. Emphasis is given to the application and outlook of thiol–ene cross-linked hydrogels.

scholarly journals Zein as a versatile biopolymer: different shapes for different biomedical applications

RSC Advances ◽  
2021 ◽  
Vol 11 (62) ◽  
pp. 39004-39026
Author(s):  
Silvia Tortorella ◽  
Mirko Maturi ◽  
Veronica Vetri Buratti ◽  
Giulia Vozzolo ◽  
Erica Locatelli ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
3D Scaffolds ◽  
Different Shapes ◽  
Biomedical Field

Zein a versatile biomaterial in the biomedical field. Easy to chemically functionalize with good emulsification properties, can be employed in drug delivery, fabrication of bioactive membranes and 3D scaffolds for tissue regeneration.

scholarly journals Custom on demand 3D printing of functional microstructures

2015 ◽  
Vol 55 (3) ◽  
Author(s):  
Linas Jonušauskas ◽  
Edvinas Skliutas ◽  
Simas Butkus ◽  
Mangirdas Malinauskas
Keyword(s):  
3D Printing ◽  
Biomedical Applications ◽  
Laser Light ◽  
Rapid Development ◽  
Ultrafast Laser ◽  
Direct Laser Writing ◽  
Fused Filament Fabrication ◽  
3D Scaffolds ◽  
On Demand ◽  
Direct Laser

Rapid development in 3D printing technologies promises a cheap and simple yet reliable way for producing various components and structures for research in numerous science fields. This work is dedicated to investigate the possibility to use fused filament fabrication based 3D printing to fabricate microchannels for microfluidical applications as well as diverse 3D scaffolds for biomedical applications. We also examine the possibility to further improve fabricated structures by employing an ultrafast laser, namely by laser light filamentation and using direct laser writing. Results of this study are discussed in detail and outlook for further work in this field is given.

scholarly journals Open Porous Composite Monoliths for Biomedical Applications via Photocrosslinking of Low Internal Phase Nano-Emulsion Templates

2021 ◽  
Vol 11 (12) ◽  
pp. 5338
Author(s):  
Maurizio Celentano ◽  
Raffaele Vecchione ◽  
Maddalena De Simone ◽  
Eliana Esposito ◽  
Monica Patrone ◽  
...  
Keyword(s):  
Polymer Matrix ◽  
Biomedical Applications ◽  
Morphological Alterations ◽  
Permeable Media ◽  
Internal Phase ◽  
Complex Shapes ◽  
Oxidase Enzyme ◽  
Nano Emulsion ◽  
Oxidation Of Glucose ◽  
Porous Morphology

Highly cross-linked polyethylene glycol monoliths (HCPEG) with interconnected micro and nanoporosity are produced via photo-crosslinking of low internal phase emulsions (LIPE). Unlike previous works, this approach allows the pre-processing functionalization of both polymer matrix and porosity by loading both phases of the emulsion template with several active fillers, such as enzymes, semiconductive polymers, and metallic nanostructures. Importantly, both polymer matrix and porosity of the resulting composite HCPEG monoliths show neither serious cross-contamination nor morphological alterations. All in all, this material behaves like a network of nano/micro flasks embedded into a permeable media. Mechanical and dielectric properties of these composites HCPEG monoliths can be tuned by varying the content of fillers. Since these composite materials are produced by photo-crosslinking of LIPEs, they can be easily and rapidly processed into complex shapes like microneedles arrays through replica molding without detrimental modifications of the porous morphology. In principle, the proposed strategy allows us to fabricate medical devices. As proof of concept, we embedded glucose oxidase enzyme in the nanoporosity and the resulting composite porous material retained the catalytic activity towards the oxidation of glucose.

scholarly journals Porous Polymers from High Internal Phase Emulsions as Scaffolds for Biological Applications

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1786
Author(s):  
Stanko Kramer ◽  
Neil R. Cameron ◽  
Peter Krajnc
Keyword(s):  
Cell Growth ◽  
Biomedical Applications ◽  
Wide Spectrum ◽  
Continuous Phase ◽  
Porous Polymer ◽  
Porous Polymers ◽  
Biological Cell ◽  
Biological Applications ◽  
Internal Phase ◽  
Advanced Applications

High internal phase emulsions (HIPEs), with densely packed droplets of internal phase and monomers dispersed in the continuous phase, are now an established medium for porous polymer preparation (polyHIPEs). The ability to influence the pore size and interconnectivity, together with the process scalability and a wide spectrum of possible chemistries are important advantages of polyHIPEs. In this review, the focus on the biomedical applications of polyHIPEs is emphasised, in particular the applications of polyHIPEs as scaffolds/supports for biological cell growth, proliferation and tissue (re)generation. An overview of the polyHIPE preparation methodology is given and possibilities of morphology tuning are outlined. In the continuation, polyHIPEs with different chemistries and their interaction with biological systems are described. A further focus is given to combined techniques and advanced applications.

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