scholarly journals Fast transformation of 2D nanofiber membranes into pre-molded 3D scaffolds with biomimetic and oriented porous structure for biomedical applications

2020 ◽  
Vol 7 (2) ◽  
pp. 021406 ◽  
Author(s):  
Shixuan Chen ◽  
Johnson V. John ◽  
Alec McCarthy ◽  
Mark A. Carlson ◽  
Xiaowei Li ◽  
...  
Keyword(s):  
Porous Structure ◽  
Biomedical Applications ◽  
3D Scaffolds ◽  
Nanofiber Membranes

scholarly journals Surface Properties and Biocompatibility of Anodized Titanium with a Potential Pretreatment for Biomedical Applications

Metals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1090
Author(s):  
Bai-Hung Huang ◽  
Yi-Jung Lu ◽  
Wen-Chien Lan ◽  
Muhammad Ruslin ◽  
Hung-Yang Lin ◽  
...  
Keyword(s):  
Porous Structure ◽  
Biomedical Applications ◽  
Grazing Incidence ◽  
Acid Pretreatment ◽  
Osteoblast Cells ◽  
In Vitro Biocompatibility ◽  
Porous Ti ◽  
Diphenyltetrazolium Bromide ◽  
Anodized Titanium

The effects of anodized titanium (Ti) with a potential hydrogen fluoride (HF) acid pretreatment through cathodization on the formation of nano-porous Ti dioxide (TiO2) layer were characterized using field-emission scanning electron microscopy, grazing incidence X-ray diffractometer, and contact angle goniometer. The biocompatibility was determined by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) test. Analytical results found that a well-aligned nano-porous structure was formed on the anodized Ti surface with HF pretreatment concentration above 0.5%. Microstructure of the nano-porous Ti dioxide surface generated by anodization with HF pretreatment was composed of anatase and rutile phases, while the anodized Ti sample with HF pretreatment concentration of 0.5% presented excellent hydrophilicity surface. An in-vitro biocompatibility also indicated that osteoblast cells grown on the surface of the anodized Ti sample with HF pretreatment increased with the increase of culture time. The filopodia of osteoblast cells not only adhered flat, but also tightly grabbed the nano-porous structure for promoting cell adhesion and proliferation. Therefore, the anodized Ti with HF pretreatment can form a functionalized surface with great biocompatibility for biomedical applications, particularly for dental implants.

Femtosecond laser structuring of permeable and resorbable biomaterial

2021 ◽  
Vol 7 (2) ◽  
pp. 713-716
Author(s):  
Swen Grossmann ◽  
Sabine Illner ◽  
Robert Ott ◽  
Grit Rhinow ◽  
Carsten Tautorat ◽  
...  
Keyword(s):  
Femtosecond Laser ◽  
Biomedical Applications ◽  
Mechanical Characteristics ◽  
Membrane Properties ◽  
Fiber Network ◽  
Laser Technology ◽  
Laser Structuring ◽  
Wide Range ◽  
Nanofiber Membranes ◽  
Post Production

Abstract Bioresorbable nanofiber nonwovens with their fascinating properties provide a wide range of potential biomedical applications. Modification of the material enables the adjustment of mechanical and biological characteristics depending on the desired application. Due to the nanosized fiber network, post-production structuring is very challenging. Within this study, we use femtosecond laser technology for structuring permeable and resorbable electrospun poly-L-lactide (PLLA) membranes. We show that this post-production process can be used without disturbing the fiber network near the structured areas. Furthermore, the modification of the water permeability and mechanical characteristics due to the laser structuring was investigated. The results prove femtosecond laser technology to be a promising method for the adjustment of the membrane properties and which in consequence can help to optimize cell adhesion, enable revascularization and open up applications of nanofiber membranes in personalized medicine.

scholarly journals 3D Scaffolds Based on Conductive Polymers for Biomedical Applications

2018 ◽  
Vol 20 (1) ◽  
pp. 73-89 ◽  
Author(s):  
Nuria Alegret ◽  
Antonio Dominguez-Alfaro ◽  
David Mecerreyes
Keyword(s):  
Biomedical Applications ◽  
Conductive Polymers ◽  
3D Scaffolds

Regenerative medicine under control of 3D scaffolds: Current state and progress of tissue scaffolds

2020 ◽  
Vol 15 ◽  
Author(s):  
Ali Golchin ◽  
Sina Farzaneh ◽  
Bahareh Porjabbar ◽  
Fatemeh Sadegian ◽  
Masoumeh Estaji ◽  
...  
Keyword(s):  
Regenerative Medicine ◽  
Cell Fate ◽  
Biomedical Applications ◽  
Three Dimensional ◽  
3D Scaffold ◽  
3D Scaffolds ◽  
Nutrient Delivery ◽  
Cell Functions ◽  
Current State ◽  
Biomaterial Scaffolds

: Currently, combining stem cells [SCs] with biomaterial scaffolds provides a promising strategy for the future of biomedicine and regenerative medicine [RG]. The cells need similar substrates of extra cellular matrix [ECM] for normal tissue development that signifies the importance of three dimensional [3D] scaffolds to determine cell fate. Herein, we present the great importance and also positive contributions of corresponding 3D scaffolds on cell functions including cell interactions, cell migrations, and nutrient delivery. Further on, the synthesis techniques which are recruited to fabricate the 3D scaffolds, are discussed besides the related studies of 3D scaffold for different tissues are reported in this paper completely. This review focuses on 3D scaffolds that have been used for tissue engineering purposes and directing stem cell fate as a means of producing replacements for biomedical applications.

scholarly journals On Various Porous Scaffold Fabrication Methods

2017 ◽  
Vol 16 (4) ◽  
pp. 47-52 ◽  
Author(s):  
D Elamparithi ◽  
V Moorthy
Keyword(s):  
Porous Structure ◽  
Biomedical Applications ◽  
Therapeutic Potential ◽  
Porous Scaffold ◽  
Three Dimensional ◽  
Porous Scaffolds ◽  
Preparation Methods ◽  
Advantages And Disadvantages ◽  
And Migration ◽  
Preparation Techniques

Three-dimensional scaffolds can be fabricated by various methods. These scaffold constructs showed a major impact on various biomedical applications. The bioactive porous scaffolds should have an excellent three-dimensional architecture and interconnected porous structure for cells adhesion and migration to enhance the therapeutic potential. The porosity and interconnected porous structure can be optimized using various scaffold preparation methods. In this mini review, we discussed the advantages and disadvantages of various commonly used scaffold preparation techniques.

scholarly journals Development of shape memory polymers micro/nanofiber membranes in biomedical applications

2018 ◽  
Vol 48 (8) ◽  
pp. 811-826 ◽  
Author(s):  
Wei ZHENG ◽  
YaLi WANG ◽  
FengHua ZHANG ◽  
ChunYan LI ◽  
YanJu LIU ◽  
...  
Keyword(s):  
Shape Memory ◽  
Biomedical Applications ◽  
Shape Memory Polymers ◽  
Nanofiber Membranes
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