scholarly journals Ultrasensitive and specific fluorescence detection of a cancer biomarkerviananomolar binding to a guanidinium-modified calixarene

2018 ◽  
Vol 9 (8) ◽  
pp. 2087-2091 ◽  
Author(s):  
Zhe Zheng ◽  
Wen-Chao Geng ◽  
Jie Gao ◽  
Yu-Ying Wang ◽  
Hongwei Sun ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
Lysophosphatidic Acid ◽  
Potential Application ◽  
Cancer Biomarker ◽  
Gynecologic Cancers ◽  
Specific Fluorescence

A well-designed macrocycle affords nanomolar binding to a cancer biomarker lysophosphatidic acid, showing potential application in the diagnosis of gynecologic cancers.

scholarly journals Surface Adsorption of the Cancer Biomarker Lysophosphatidic Acid in Serum Studied by Acoustic Wave Biosensor

Materials ◽  
2021 ◽  
Vol 14 (15) ◽  
pp. 4158
Author(s):  
Brian De La Franier ◽  
Michael Thompson
Keyword(s):  
Acoustic Wave ◽  
Lysophosphatidic Acid ◽  
Electrode Surface ◽  
Biological Fluids ◽  
Thiol Group ◽  
Cancer Biomarker ◽  
Specific Adsorption ◽  
Shear Mode ◽  
Serum Samples ◽  
Fouling Reduction

The thickness shear mode acoustic wave device is of interest for the sensing of biomarkers for diseases in various biological fluids, but suffers from the issue of non-specific adsorption of compounds other than those of interest to the electrode surface, thus affecting the device’s output. The aim of this present study was to determine the level of non-specific adsorption on gold electrodes from serum samples with added ovarian cancer biomarker lysophosphatidic acid in the presence of a surface anti-fouling layer. The latter was an oligoethylene molecule with thiol group for attachment to the electrode surface. It was found that the anti-fouling layer had a minimal effect on the level of both adsorption of components from serum and the marker. This result stands in sharp contrast to the analogous monolayer employed for anti-fouling reduction on silica.

Sequence-Specific Fluorescence Detection of DNA by Polyamide−Thiazole Orange Conjugates

2005 ◽  
Vol 127 (47) ◽  
pp. 16685-16691 ◽  
Author(s):  
Eric J. Fechter ◽  
Bogdan Olenyuk ◽  
Peter B. Dervan
Keyword(s):  
Fluorescence Detection ◽  
Thiazole Orange ◽  
Specific Fluorescence

A chromo- and fluorogenic sensor for probing the cancer biomarker lysophosphatidic acid

The Analyst ◽  
2012 ◽  
Vol 137 (8) ◽  
pp. 1853 ◽  
Author(s):  
Wenwen Zhao ◽  
Weimin Liu ◽  
Wenjun Zhang ◽  
Lintao Zeng ◽  
Zhiyuan Fan ◽  
...  
Keyword(s):  
Lysophosphatidic Acid ◽  
Cancer Biomarker

Verification of GM2 Activator Protein for Potential Application as Lung Cancer Biomarker

2015 ◽  
Vol 4 (4) ◽  
pp. 280-287
Author(s):  
Laddawan. Potprommanee ◽  
Kongsak. Boonyapranai ◽  
Padchanee. Sangthong ◽  
Busayamass. Chewaskulyong ◽  
Shui-Tein. Chen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Potential Application ◽  
Cancer Biomarker ◽  
Activator Protein ◽  
Gm2 Activator ◽  
Lung Cancer Biomarker ◽  
Gm2 Activator Protein

scholarly journals Sequence Specific Fluorescence Detection of Double Strand DNA  [J. Am. Chem. Soc.2003,125, 1195−1202].

2003 ◽  
Vol 125 (19) ◽  
pp. 6008-6008
Author(s):  
Victor C. Rucker ◽  
Shane Foister ◽  
Christian Melander ◽  
Peter B. Dervan
Keyword(s):  
Fluorescence Detection ◽  
Specific Fluorescence ◽  
Double Strand Dna

Sequence Specific Fluorescence Detection of Double Strand DNA

2003 ◽  
Vol 125 (5) ◽  
pp. 1195-1202 ◽  
Author(s):  
Victor C. Rucker ◽  
Shane Foister ◽  
Christian Melander ◽  
Peter B. Dervan
Keyword(s):  
Fluorescence Detection ◽  
Specific Fluorescence ◽  
Double Strand Dna
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