A combination of quercetin and resveratrol reduces obesity in high-fat diet-fed rats by modulation of gut microbiota

2017 ◽  
Vol 8 (12) ◽  
pp. 4644-4656 ◽  
Author(s):  
Le Zhao ◽  
Qi Zhang ◽  
Weini Ma ◽  
Feng Tian ◽  
Hongyi Shen ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
High Fat Diet ◽  
High Fat ◽  
Beneficial Effects ◽  
Gut Microbiota Dysbiosis

Administration of a combination of quercetin and resveratrol may have beneficial effects on ameliorating HFD-induced obesity and reducing HFD-induced gut microbiota dysbiosis.

The ameliorative effect of the Pyracantha fortuneana (Maxim.) H. L. Li extract on intestinal barrier dysfunction through modulating glycolipid digestion and gut microbiota in high fat diet-fed rats

2019 ◽  
Vol 10 (10) ◽  
pp. 6517-6532 ◽  
Author(s):  
Hang Xu ◽  
Chunfang Zhao ◽  
Yutian Li ◽  
Ruiyu Liu ◽  
Mingzhang Ao ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
High Fat Diet ◽  
Intestinal Barrier ◽  
High Fat ◽  
Barrier Dysfunction ◽  
Fruit Extract ◽  
Intestinal Barrier Dysfunction ◽  
Beneficial Effects ◽  
Obese Rats ◽  
Ameliorative Effect

Pyracantha fortuneana fruit extract (PFE) exhibits beneficial effects on IBF in association with the modulation of glycolipid digestion and gut microbiota in HFD-fed obese rats.

scholarly journals Steatosis and gut microbiota dysbiosis induced by high-fat diet are reversed by 1-week chow diet administration

2019 ◽  
Vol 71 ◽  
pp. 72-88 ◽  
Author(s):  
Zahra Safari ◽  
Magali Monnoye ◽  
Peter M. Abuja ◽  
Mahendra Mariadassou ◽  
Karl Kashofer ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
High Fat Diet ◽  
Chow Diet ◽  
High Fat ◽  
Gut Microbiota Dysbiosis

A comparison between whole mung bean and decorticated mung bean: beneficial effects on the regulation of serum glucose and lipid disorders and the gut microbiota in high-fat diet and streptozotocin-induced prediabetic mice

2020 ◽  
Vol 11 (6) ◽  
pp. 5525-5537 ◽  
Author(s):  
Dianzhi Hou ◽  
Qingyu Zhao ◽  
Laraib Yousaf ◽  
Borui Chen ◽  
Yong Xue ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
High Fat Diet ◽  
Mung Bean ◽  
Serum Glucose ◽  
High Fat ◽  
Beneficial Effects ◽  
Lipid Disorders

This study aimed to investigate the beneficial effects of whole and decorticated mung beans on the regulation of serum glucose and lipid disorders in HFD/STZ-induced prediabetic mice, and to further explore their gut microbiota modulatory effects.

Effects of high-fat diet-induced gut microbiota dysbiosis: far beyond the gut

Gut ◽  
2020 ◽  
Vol 69 (12) ◽  
pp. 2259.1-2259 ◽  
Author(s):  
Tianyu Liu ◽  
Bangmao Wang ◽  
Hailong Cao
Keyword(s):  
Gut Microbiota ◽  
High Fat Diet ◽  
High Fat ◽  
Gut Microbiota Dysbiosis

A fucoidan from sea cucumber Pearsonothuria graeffei with well-repeated structure alleviates gut microbiota dysbiosis and metabolic syndromes in HFD-fed mice

2018 ◽  
Vol 9 (10) ◽  
pp. 5371-5380 ◽  
Author(s):  
Shan Li ◽  
Junhui Li ◽  
Guizhu Mao ◽  
Tiantian Wu ◽  
Yaqin Hu ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
High Fat Diet ◽  
Sea Cucumber ◽  
Major Contributor ◽  
High Fat ◽  
Repeated Structure ◽  
Gut Microbiota Dysbiosis ◽  
Metabolic Syndromes

A high-fat diet (HFD) has been a major contributor to increasing morbidity caused by metabolic syndromes.

scholarly journals Structural Characterization of Peptides From Huangjiu and Their Regulation of Hepatic Steatosis and Gut Microbiota Dysbiosis in Hyperlipidemia Mice

2021 ◽  
Vol 12 ◽  
Author(s):  
Ying Shi ◽  
Ruixue Feng ◽  
Jieqi Mao ◽  
Shuangping Liu ◽  
Zhilei Zhou ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Hepatic Steatosis ◽  
High Fat Diet ◽  
Bioactive Peptides ◽  
Size Analysis ◽  
High Fat ◽  
Linear Discriminant ◽  
Wide Range ◽  
Gut Microbiota Dysbiosis

Hyperlipidemia is a chronic disorder that is difficult to cure and usually treated with long-term lipid-reducing drugs. Recent trends have led to the use of diet therapies or food-derived strategies in the treatment of such long-term diseases. The Chinese rice wine (huangjiu) contains a wide range of bioactive peptides that are produced during the multi-species fermentation process. To clarify the regulation effects of lipid metabolism and gut microbiota by huangjiu bioactive peptides, three huangjiu peptides were isolated, purified and characterized by hyper-filtration, macroporous resin, gel filtration separation and structural identification. Meanwhile, a mouse model of high-fat diet-induced hyperlipidemia was established to study the effects of huangjiu peptides on serum biomarker, hepatic metabolism and gut microbiota dysbiosis. Experimental results showed that huangjiu peptides T1 and T2 (HpT1, HpT2) treatment alleviated the increase in serum total cholesterol, triglyceride, low-density lipoprotein cholesterol levels and aberrant hepatic lipid accumulation in the high-fat diet-induced hyperlipidemia mice. Furthermore, HpT2 and HpT1 restored the α-diversity and structure of gut microbial community after hyperlipidemia-induced microbiota disturbance compared with simvastatin and HpT3. The administration of HpT2 and HpT1 regulated the microbiota-mediated gut ecology through alterations of characteristic taxa including Lactobacillus, Ileibacterium, Faecalibaculum and Alloprevotella by linear discriminant analysis effect size analysis. Collectively, our results offer new insights into the abilities of food-derived peptides on alleviation of high-fat diet-induced hyperlipidemia, hepatic steatosis and gut dysbiosis in mice.

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