Copper-catalyzed radical cascade oxyalkylation of olefinic amides with simple alkanes: highly efficient access to benzoxazines

2017 ◽  
Vol 53 (56) ◽  
pp. 7961-7964 ◽  
Author(s):  
Jie Wang ◽  
Ruoyu Sang ◽  
Xiaolong Chong ◽  
Yinuo Zhao ◽  
Wenjie Fan ◽  
...  
Keyword(s):  
Bond Functionalization ◽  
Highly Efficient ◽  
Efficient Access ◽  
Radical Cascade

A copper-catalyzed C(sp3)–H bond functionalization of simple alkanes with olefinic amides was developed for the synthesis of benzoxazine derivatives.

Enantioselective synthesis of tetrahydroisoquinolines via catalytic intramolecular asymmetric reductive amination

2021 ◽  
Author(s):  
Ruixia Liu ◽  
Jingkuo Han ◽  
Bin Li ◽  
Xian Liu ◽  
Zhao Wei ◽  
...  
Keyword(s):  
Reductive Amination ◽  
Enantioselective Synthesis ◽  
Iridium Complex ◽  
Highly Efficient ◽  
Efficient Access

A highly efficient intramolecular asymmetric reductive amination transformation catalyzed by an iridium complex of tBu-ax-Josiphos has been realized, providing an efficient access to various THIQ alkaloids.

scholarly journals Recent Developments in Polyene Cyclizations and Their Applications in Natural Product Synthesis

Synthesis ◽  
2018 ◽  
Vol 51 (01) ◽  
pp. 67-82 ◽  
Author(s):  
Anthony Barrett ◽  
Tsz-Kan Ma ◽  
Thomas Mies
Keyword(s):  
Transition Metal ◽  
Natural Product ◽  
Lewis Acid ◽  
Multiple Bond ◽  
Natural Product Synthesis ◽  
Cyclization Reactions ◽  
Cascade Cyclizations ◽  
Highly Efficient ◽  
Recent Developments ◽  
Radical Cascade

Cascade polyene cyclization reactions are highly efficient and elegant bioinspired transformations that involve simultaneous multiple bond constructions to rapidly generate complex polycyclic molecules. This review summarizes the most prominent work on a variety of cationic and radical cascade cyclizations and their applications in natural product synthesis published between 2014 and 2018.1 Introduction2 Cationic Polyene Cyclizations2.1 Lewis Acid Mediated Polyene Cyclizations2.2 Brønsted Acid Mediated Polyene Cyclizations2.3 Halogen Electrophile Initiated Polyene Cyclizations2.4 Sulfur Electrophile Initiated Polyene Cyclizations2.5 Transition-Metal-Mediated Cationic Polyene Cyclizations3 Radical Polyene Cyclizations3.1 Transition-Metal-Mediated Radical Polyene Cyclizations3.2 Photocatalyst-Mediated Polyene Cyclizations4 Origin of Stereocontrol in Polyene Cyclizations5 Conclusion

Metal-free radical cascade dichloromethylation of activated alkenes using CH2Cl2: highly selective activation of the C–H bond

RSC Advances ◽  
2014 ◽  
Vol 4 (110) ◽  
pp. 64855-64859 ◽  
Author(s):  
Yunfei Tian ◽  
Zhong-Quan Liu
Keyword(s):  
Free Radical ◽  
Dicumyl Peroxide ◽  
Cascade Process ◽  
Selective Activation ◽  
Metal Free ◽  
Efficient Access ◽  
Radical Cascade

A dicumyl peroxide-initiated highly selective activation of the (sp3)C–H bond in dichloromethane (DCM, CH2Cl2) has been achieved, which allows efficient access to dichloronated oxindoles via a free-radical cascade process.

scholarly journals Highly Efficient Access to Strained Bicyclic Ketals via Gold-Catalyzed Cycloisomerization of Bis-homopropargylic Diols.

ChemInform ◽  
2005 ◽  
Vol 36 (46) ◽  
Author(s):  
Sylvain Antoniotti ◽  
Emilie Genin ◽  
Veronique Michelet ◽  
Jean-Pierre Genet
Keyword(s):  
Highly Efficient ◽  
Efficient Access

ChemInform Abstract: Copper-Catalyzed Cascade Addition/Cyclization: Highly Efficient Access to Phosphonylated Quinoline-2,4(1H,3H)-diones.

ChemInform ◽  
2015 ◽  
Vol 46 (37) ◽  
pp. no-no
Author(s):  
Ya-Min Li ◽  
Shi-Sheng Wang ◽  
Fuchao Yu ◽  
Yuehai Shen ◽  
Kwen-Jen Chang
Keyword(s):  
Highly Efficient ◽  
Efficient Access

An eco-benign and highly efficient access to 3-heterocyclic-substituted isoindolinones in ammonia water

2013 ◽  
Vol 15 (4) ◽  
pp. 896 ◽  
Author(s):  
Shao-Chun Shen ◽  
Xing-Wen Sun ◽  
Guo-Qiang Lin
Keyword(s):  
Ammonia Water ◽  
Highly Efficient ◽  
Efficient Access

Highly Efficient Access to Strained Bicyclic Ketals via Gold-Catalyzed Cycloisomerization of Bis-homopropargylic Diols

2005 ◽  
Vol 127 (28) ◽  
pp. 9976-9977 ◽  
Author(s):  
Sylvain Antoniotti ◽  
Emilie Genin ◽  
Véronique Michelet ◽  
Jean-Pierre Genêt
Keyword(s):  
Highly Efficient ◽  
Efficient Access
Sign in / Sign up

Export Citation Format

Share Document