Synergistic therapy of chemotherapeutic drugs and MTH1 inhibitors using a pH-sensitive polymeric delivery system for oral squamous cell carcinoma

2017 ◽  
Vol 5 (10) ◽  
pp. 2068-2078 ◽  
Author(s):  
Xiao Li ◽  
Lei Li ◽  
Yu Huang ◽  
Bing Liu ◽  
Huirong Chi ◽  
...  
Keyword(s):  
Dna Damage ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Cancer Cells ◽  
Delivery System ◽  
Squamous Cell ◽  
Chemotherapeutic Drugs ◽  
Polymeric Delivery ◽  
Anticancer Target

MutT homolog 1 (MTH1) is an essential sanitizer of the free nucleotide pool that prevents lethal DNA damage in cancer cells, which has been validated as an anticancer target in recent years.

Molecular Pathways Involved in Crosstalk Between Cancer Cells, Osteoblasts and Osteoclasts in the Invasion of Bone by Oral Squamous Cell Carcinoma: Erratum

Pathology ◽  
2012 ◽  
Vol 44 (4) ◽  
pp. 388
Author(s):  
Jingjing Quan ◽  
Chuanxiang Zhou ◽  
Newell W. Johnson ◽  
Glenn Francis ◽  
Jane E. Dahlstrom ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Cancer Cells ◽  
Squamous Cell ◽  
Molecular Pathways
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