Google Analytics and quick response for advancement of gold nanoparticle-based dual lateral flow immunoassay for malaria – Plasmodium lactate dehydrogenase (pLDH)

2017 ◽  
Vol 9 (41) ◽  
pp. 5943-5951 ◽  
Author(s):  
Christian L. Mthembu ◽  
Myalowenkosi I. Sabela ◽  
Mbuso Mlambo ◽  
Lawrence M. Madikizela ◽  
Suvardhan Kanchi ◽  
...  
Keyword(s):  
Lactate Dehydrogenase ◽  
Gold Nanoparticle ◽  
Healthcare Workers ◽  
Malaria Diagnosis ◽  
Lateral Flow ◽  
Lateral Flow Immunoassay ◽  
Quick Response ◽  
Community Healthcare ◽  
Community Healthcare Workers

An assay with quick response barcodes improves malaria diagnosis, and enhances systems transferring data among community healthcare workers.

A remarkable sensitivity enhancement in a gold nanoparticle-based lateral flow immunoassay for the detection of Escherichia coli O157:H7

RSC Advances ◽  
2015 ◽  
Vol 5 (56) ◽  
pp. 45092-45097 ◽  
Author(s):  
Xi Cui ◽  
Youju Huang ◽  
Jingyun Wang ◽  
Lei Zhang ◽  
Yun Rong ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Gold Nanoparticle ◽  
Quantitative Data ◽  
Visual Inspection ◽  
Sensitivity Enhancement ◽  
Lateral Flow ◽  
Lateral Flow Immunoassay ◽  
Escherichia Coli O157

The size and uniformity of AuNPs were optimized to maximally amplify both visual inspection signals and quantitative data of LFA.

scholarly journals Designing an integrated, nurse-driven and home-based digital intervention to improve insulin management in under-resourced settings

2021 ◽  
Vol 12 ◽  
pp. 204201882110546
Author(s):  
Patrick Ngassa Piotie ◽  
Paola Wood ◽  
Elizabeth M. Webb ◽  
Johannes F.M. Hugo ◽  
Paul Rheeder
Keyword(s):  
South Africa ◽  
Type 2 Diabetes ◽  
Primary Care ◽  
Healthcare Workers ◽  
Digital Health ◽  
Complex Interventions ◽  
Community Healthcare ◽  
Community Healthcare Workers ◽  
Project Intervention

Background: In South Africa, initiating insulin for people with type 2 diabetes and subsequent titration is a major challenge for the resource-constrained healthcare system. Inadequate support systems in primary care, including not being able to access blood glucose monitors and test strips for self-monitoring of blood glucose, results in patients with type 2 diabetes being referred to higher levels of care. In primary care, initiation of insulin may be delayed due to a shortage of healthcare workers. The delayed initiation of insulin is also exacerbated by the reported resistance of both healthcare providers and people with type 2 diabetes to start insulin. In South Africa, telehealth provides an opportunity to overcome these challenges and manage insulin therapy in primary care. Methods: We describe the development of a digital health intervention including the framework used, the theoretical approach and subsequent implementation strategies. Results: This intervention is an innovative, nurse-driven and app-enabled intervention called ‘the Tshwane Insulin Project intervention’. The Tshwane Insulin Project intervention was designed and evaluated using the framework recommended by the Medical Research Council for complex interventions. The Tshwane Insulin Project intervention was developed in four sequential phases: planning, design, implementation and evaluation. The Tshwane Insulin Project intervention followed the Integrated Chronic Disease Management framework to facilitate implementation and acceptability. The Tshwane Insulin Project comprises a facility-level intervention, where nurses evaluate patients and initiate insulin, an individual-level intervention where community healthcare workers visit patients at their homes to follow-up and provide educational information, while using telehealth to enable physician-directed insulin titration if needed, and a community-level intervention aimed at empowering community healthcare workers to support people living with diabetes and raise awareness of diabetes. Conclusion: The technological advancements in digital health and telemedicine present an opportunity to improve diabetes care in resource-limited countries. This work can inform those intending to develop and implement complex interventions in primary healthcare in developing countries.

scholarly journals Serologic SARS-CoV-2 testing in healthcare workers with positive RT-PCR test or Covid-19 related symptoms

2020 ◽  
Author(s):  
Giovanni Visci ◽  
Vittorio Lodi ◽  
Roberta Bonfiglioli ◽  
Tiziana Lazzarotto ◽  
Francesco S. Violante ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Lateral Flow ◽  
Public Hospitals ◽  
Lateral Flow Immunoassay ◽  
Enzyme Linked Immunosorbent Assay ◽  
Limited Information ◽  
Rt Pcr ◽  
Positive Serology ◽  
Serologic Response ◽  
Pcr Test

AbstractBackgroundLimited information is available on prevalence and determinants of serologic response to SARS-CoV-2 infection among healthcare workers (HCWs).MethodsWe analyzed the results of serologic testing with chemiluminescence immunoassay analyzer (CLIA), lateral flow immunoassay (LFIA) and enzyme-linked immunosorbent assay (ELISA) test among 544 HCWs with at least one positive RT-PCR test and 157 HCWs with Covid-19 related symptoms without a positive RT-PCR test from public hospitals in Bologna, Northern Italy. Tests were performed between March and August 2020. We fitted multivariate logistic regression models to identify determinants of positive serology.ResultsThe sensitivity of SARS-CoV-2 was 75.2% (LFIA) and 90.6% (CLIA). No differences in seropositivity were observed by sex, while older HCWs had higher positivity than other groups, and nurses had higher positivity compared to physicians, but not other HCWs. An estimated 73.4% of HCWs with Covid-19 symptoms without RT-PCR test were not infected with SARS-CoV-2.ConclusionsOur study provides the best available data on sensitivity of serologic tests and on determinants of serologic response among HCWs positive for SARS-CoV-2, and provide evidence on the low specificity of Covid-19 related symptoms to identify infected HCWs.SummaryThe sensitivity of SARS-CoV-2 lateral flow immunoassay serology in healthcare workers (HCWs) was 75.2%. Older HCWs and nurses had higher positivity than other groups. An estimated 73.4% of HCWs with Covid-19 symptoms without RT-PCR test were not infected with SARS-CoV-2.

Sign in / Sign up

Export Citation Format

Share Document