A novel nanohybrid for cancer theranostics: folate sensitized Fe2O3nanoparticles for colorectal cancer diagnosis and photodynamic therapy

2017 ◽  
Vol 5 (21) ◽  
pp. 3927-3939 ◽  
Author(s):  
Ramesh Nandi ◽  
Snehasis Mishra ◽  
Tuhin Kumar Maji ◽  
Krishnendu Manna ◽  
Prasenjit Kar ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Photodynamic Therapy ◽  
Folic Acid ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Cancer Diagnosis ◽  
Oxide Nanoparticles ◽  
Cancer Theranostics

Folic acid functionalized iron oxide nanoparticles for colorectal cancer theranostics application.

Shaping and Cellular Uptake of Folic Acid Coated Gold and Magnetite Nanoparticles

2019 ◽  
Vol 9 (2) ◽  
pp. 166-172
Author(s):  
Ahmed A.G. El-Shahawy ◽  
Gamal Elghnam ◽  
Alsayed A.M. Alsherbini
Keyword(s):  
Folic Acid ◽  
Iron Oxide ◽  
Tumor Cells ◽  
Iron Oxide Nanoparticles ◽  
Individual Cell ◽  
Oxide Nanoparticles ◽  
Cellular Compartment ◽  
Specific Tumor ◽  
Uv Visible

Background:Gold and Iron Oxide nanoparticles NPs play as nanocarriers for a specific drug delivery and contrast agents. Intercellular uptake of these nanoparticles and targeting to individual cell and sub-cellular compartment is essential.Objective:The aim of the current study is to evaluate the intracellular uptake of these NPs to specific tumor cells in vitro conjugated with folic acid with a goal of enhancing the efficiency of specific targeting to tumor cells.Methods:We synthesized the nanoparticles by a chemical method and characterized by UV-Visible, FTIR, XRD, and TEM.Results & Conclusion:The results revealed the conjugation of Gold and Iron Oxide nanoparticles with folic acid increased the intercellular uptake with high percent compared to non- conjugated nanoparticles.

scholarly journals Continuously manufactured single-core iron oxide nanoparticles for cancer theranostics as valuable contribution in translational research

2020 ◽  
Vol 2 (10) ◽  
pp. 4510-4521 ◽  
Author(s):  
Regina Bleul ◽  
Abdulkader Baki ◽  
Christian Freese ◽  
Hendrik Paysen ◽  
Olaf Kosch ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Translational Research ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Valuable Contribution ◽  
Therapeutic Applications ◽  
Cancer Theranostics

A micromixer platform for continuously manufactured single-core iron oxide nanoparticles for diagnostic and therapeutic applications contributing to translational research.

Facile synthesis of folic acid-functionalized iron oxide nanoparticles with ultrahigh relaxivity for targeted tumor MR imaging

2015 ◽  
Vol 3 (28) ◽  
pp. 5720-5730 ◽  
Author(s):  
Jingchao Li ◽  
Yong Hu ◽  
Jia Yang ◽  
Wenjie Sun ◽  
Hongdong Cai ◽  
...  
Keyword(s):  
Folic Acid ◽  
Iron Oxide ◽  
Mr Imaging ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Facile Synthesis

Folic acid-functionalized iron oxide nanoparticles with an ultrahigh r2 relaxivity can be formed for targeted MR imaging of tumors.

Facile synthesis of novel hydrophilic and carboxyl-amine functionalized superparamagnetic iron oxide nanoparticles for biomedical applications

RSC Advances ◽  
2016 ◽  
Vol 6 (102) ◽  
pp. 99948-99959 ◽  
Author(s):  
Ganeshlenin Kandasamy ◽  
Sreeraj Surendran ◽  
Anindita Chakrabarty ◽  
S. N. Kale ◽  
Dipak Maity
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Superparamagnetic Iron Oxide ◽  
Water Soluble ◽  
Oxide Nanoparticles ◽  
Facile Synthesis ◽  
Amine Functionalized ◽  
One Step ◽  
Cancer Theranostics

We report a one-step facile synthesis of novel water-soluble and functionalized SPIONs, which could be promising candidates for cancer theranostics.

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