scholarly journals Continuously manufactured single-core iron oxide nanoparticles for cancer theranostics as valuable contribution in translational research

2020 ◽  
Vol 2 (10) ◽  
pp. 4510-4521 ◽  
Author(s):  
Regina Bleul ◽  
Abdulkader Baki ◽  
Christian Freese ◽  
Hendrik Paysen ◽  
Olaf Kosch ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Translational Research ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Valuable Contribution ◽  
Therapeutic Applications ◽  
Cancer Theranostics

A micromixer platform for continuously manufactured single-core iron oxide nanoparticles for diagnostic and therapeutic applications contributing to translational research.

Facile synthesis of novel hydrophilic and carboxyl-amine functionalized superparamagnetic iron oxide nanoparticles for biomedical applications

RSC Advances ◽  
2016 ◽  
Vol 6 (102) ◽  
pp. 99948-99959 ◽  
Author(s):  
Ganeshlenin Kandasamy ◽  
Sreeraj Surendran ◽  
Anindita Chakrabarty ◽  
S. N. Kale ◽  
Dipak Maity
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Superparamagnetic Iron Oxide ◽  
Water Soluble ◽  
Oxide Nanoparticles ◽  
Facile Synthesis ◽  
Amine Functionalized ◽  
One Step ◽  
Cancer Theranostics

We report a one-step facile synthesis of novel water-soluble and functionalized SPIONs, which could be promising candidates for cancer theranostics.

Iron oxide nanoparticles conjugated with organic optical probes for in vivo diagnostic and therapeutic applications

Nanomedicine ◽  
2021 ◽  
Author(s):  
Shalini Sharma ◽  
Nisha Lamichhane ◽  
Parul ◽  
Tapas Sen ◽  
Indrajit Roy
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Optical Probe ◽  
Inorganic Nanoparticles ◽  
Oxide Nanoparticles ◽  
Optical Probes ◽  
Therapeutic Applications

The role and scope of functional inorganic nanoparticles in biomedical research is well established. Among these, iron oxide nanoparticles (IONPs) have gained maximum attention as they can provide targeting, imaging and therapeutic capabilities. Furthermore, incorporation of organic optical probes with IONPs can significantly enhance the scope and viability of their biomedical applications. Combination of two or more such applications renders multimodality in nanoparticles, which can be exploited to obtain synergistic benefits in disease detection and therapy viz theranostics, which is a key trait of nanoparticles for advanced biomedical applications. This review focuses on the use of IONPs conjugated with organic optical probe/s for multimodal diagnostic and therapeutic applications in vivo.

MRI Guided Magneto-chemotherapy with High-Magnetic-Moment Iron Oxide Nanoparticles for Cancer Theranostics

2020 ◽  
Vol 3 (4) ◽  
pp. 2305-2313 ◽  
Author(s):  
Ashwini Salunkhe ◽  
Vishwajeet Khot ◽  
S. I. Patil ◽  
Syed A.M. Tofail ◽  
Joanna Bauer ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Magnetic Moment ◽  
Oxide Nanoparticles ◽  
Mri Guided ◽  
High Magnetic Moment ◽  
Cancer Theranostics

scholarly journals Superparamagnetic Iron Oxide Nanoparticles in Cancer Theranostics

2018 ◽  
Vol 2 (1) ◽  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Drug Carriers ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Hyperthermia Therapy ◽  
Cancer Theranostics ◽  
Therapy And Diagnosis ◽  
Efficacious Drug

Superparamagnetic iron oxide nanoparticles (SPIONs) have found extensive applications in both cancer therapy and diagnosis (theranostics) due to their intrinsic magnetic properties. SPIONs can be applied as contrast agents in magnetic resonance imaging while they are considered as efficacious drug carriers for targeted therapeutic systems as well as hyperthermia therapy. In this article, recent advances in application of SPIONs in the realm of cancer theranostics are reviewed. Moreover, biosafety issues arising from SPION application are briefly mentioned.

scholarly journals Superparamagnetic Iron Oxide Nanoparticles: Diagnostic Magnetic Resonance Imaging and Potential Therapeutic Applications in Neurooncology and Central Nervous System Inflammatory Pathologies, a Review

2009 ◽  
Vol 30 (1) ◽  
pp. 15-35 ◽  
Author(s):  
Jason S Weinstein ◽  
Csanad G Varallyay ◽  
Edit Dosa ◽  
Seymur Gahramanov ◽  
Bronwyn Hamilton ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Central Nervous System ◽  
Nervous System ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Therapeutic Applications

Superparamagnetic iron oxide nanoparticles have diverse diagnostic and potential therapeutic applications in the central nervous system (CNS). They are useful as magnetic resonance imaging (MRI) contrast agents to evaluate: areas of blood–brain barrier (BBB) dysfunction related to tumors and other neuroinflammatory pathologies, the cerebrovasculature using perfusion-weighted MRI sequences, and in vivo cellular tracking in CNS disease or injury. Novel, targeted, nanoparticle synthesis strategies will allow for a rapidly expanding range of applications in patients with brain tumors, cerebral ischemia or stroke, carotid atherosclerosis, multiple sclerosis, traumatic brain injury, and epilepsy. These strategies may ultimately improve disease detection, therapeutic monitoring, and treatment efficacy especially in the context of antiangiogenic chemotherapy and antiinflammatory medications. The purpose of this review is to outline the current status of superparamagnetic iron oxide nanoparticles in the context of biomedical nanotechnology as they apply to diagnostic MRI and potential therapeutic applications in neurooncology and other CNS inflammatory conditions.

Sign in / Sign up

Export Citation Format

Share Document