scholarly journals A protein–dye hybrid system as a narrow range tunable intracellular pH sensor

2016 ◽  
Vol 7 (11) ◽  
pp. 6808-6814 ◽  
Author(s):  
Palapuravan Anees ◽  
Karivachery V. Sudheesh ◽  
Purushothaman Jayamurthy ◽  
Arunkumar R. Chandrika ◽  
Ramakrishnapillai V. Omkumar ◽  
...  
Keyword(s):  
Intracellular Ph ◽  
Hybrid System ◽  
Narrow Range ◽  
Ph Sensor ◽  
Organic Dye ◽  
Live Cells ◽  
Two Component ◽  
Ph Variations

A two-component hybrid system consisting of organic dye nanoparticles (ash) and a protein (blue) at different ratios allows for the design of narrow range tunable nanoprobes for sensing and imaging of pH variations in live cells through ratiometric signalling.

Multifunctional fluorescent leucomalachite green derivatives for chemodosimetric detection of Fe3+, specific imaging of lipid droplets and intracellular pH monitoring

2019 ◽  
Vol 43 (41) ◽  
pp. 16349-16358 ◽  
Author(s):  
Thekke Thattariyil Divya ◽  
Darpan Raghav ◽  
Krishnan Rathinasamy ◽  
Lakshmi Chakkumkumarath
Keyword(s):  
Intracellular Ph ◽  
Lipid Droplets ◽  
Ph Monitoring ◽  
Live Cells ◽  
Leucomalachite Green ◽  
Ph Variations

Fluorescent leucomalachite green derivatives detect micromolar concentrations of Fe3+, specifically stain lipid droplets in live cells and monitor intracellular pH variations in microorganisms.

Fluorescent pH nanosensor based on carbon nanodots for monitoring minor intracellular pH changes

RSC Advances ◽  
2016 ◽  
Vol 6 (106) ◽  
pp. 104657-104664 ◽  
Author(s):  
Afsaneh Safavi ◽  
Raheleh Ahmadi ◽  
Zahra Mohammadpour ◽  
Jie Zhou
Keyword(s):  
Intracellular Ph ◽  
Ph Sensor ◽  
Live Cells ◽  
Carbon Nanodots ◽  
Ph Changes ◽  
Fluorescent Carbon Nanodots ◽  
Fluorescent Carbon

Fluorescent carbon nanodots were used as a sensitive, biocompatible intracellular pH sensor that can resolve minor pH differences in live cells.

scholarly journals β-Catenin is a pH sensor with decreased stability at higher intracellular pH

2018 ◽  
Vol 217 (11) ◽  
pp. 3965-3976 ◽  
Author(s):  
Katharine A. White ◽  
Bree K. Grillo-Hill ◽  
Mario Esquivel ◽  
Jobelle Peralta ◽  
Vivian N. Bui ◽  
...  
Keyword(s):  
Intracellular Ph ◽  
Protein Interactions ◽  
Mammalian Cells ◽  
Ph Sensor ◽  
Adherens Junction ◽  
Protein Protein Interactions ◽  
Adherens Junction Protein ◽  
Junction Protein ◽  
Evolutionarily Conserved ◽  
Ph Dependent

β-Catenin functions as an adherens junction protein for cell–cell adhesion and as a signaling protein. β-catenin function is dependent on its stability, which is regulated by protein–protein interactions that stabilize β-catenin or target it for proteasome-mediated degradation. In this study, we show that β-catenin stability is regulated by intracellular pH (pHi) dynamics, with decreased stability at higher pHi in both mammalian cells and Drosophila melanogaster. β-Catenin degradation requires phosphorylation of N-terminal residues for recognition by the E3 ligase β-TrCP. While β-catenin phosphorylation was pH independent, higher pHi induced increased β-TrCP binding and decreased β-catenin stability. An evolutionarily conserved histidine in β-catenin (found in the β-TrCP DSGIHS destruction motif) is required for pH-dependent binding to β-TrCP. Expressing a cancer-associated H36R–β-catenin mutant in the Drosophila eye was sufficient to induce Wnt signaling and produced pronounced tumors not seen with other oncogenic β-catenin alleles. We identify pHi dynamics as a previously unrecognized regulator of β-catenin stability, functioning in coincidence with phosphorylation.

Reversible Self-Assembly of Nanoprobes in Live Cells for Dynamic Intracellular pH Imaging

ACS Nano ◽  
2019 ◽  
Author(s):  
Bo Dong ◽  
Shuangli Du ◽  
Chunxiao Wang ◽  
Haohao Fu ◽  
Qiang Li ◽  
...  
Keyword(s):  
Intracellular Ph ◽  
Self Assembly ◽  
Live Cells ◽  
Ph Imaging

TiO2/Si nanowires hybrid system for efficient photocatalytic degradation of organic dye

2021 ◽  
Author(s):  
Krithikadevi Ramachandran ◽  
Rania Ziad ◽  
Soumya Columbus ◽  
Kais Daoudi ◽  
Jannat Hammouche ◽  
...  
Keyword(s):  
Photocatalytic Degradation ◽  
Hybrid System ◽  
Organic Dye ◽  
Si Nanowires

Ratiometric photoluminescence sensing based on Ti3C2MXene quantum dots as an intracellular pH sensor

Nanoscale ◽  
2018 ◽  
Vol 10 (3) ◽  
pp. 1111-1118 ◽  
Author(s):  
Xu Chen ◽  
Xueke Sun ◽  
Wen Xu ◽  
Gencai Pan ◽  
Donglei Zhou ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Intracellular Ph ◽  
Ph Sensor ◽  
Ph Values ◽  
Blue Photoluminescence

Surface-functionalized Ti3C2QDs exhibit bright excitation-dependent blue photoluminescence as a ratiometric pH sensor to quantitatively monitor intracellular pH values.

Nitrogen-rich functional groups carbon nanoparticles based fluorescent pH sensor with broad-range responding for environmental and live cells applications

2016 ◽  
Vol 82 ◽  
pp. 233-239 ◽  
Author(s):  
Bingfang Shi ◽  
Yubin Su ◽  
Liangliang Zhang ◽  
Rongjun Liu ◽  
Mengjiao Huang ◽  
...  
Keyword(s):  
Functional Groups ◽  
Carbon Nanoparticles ◽  
Ph Sensor ◽  
Live Cells

scholarly journals Platinum Nanoparticles as pH Sensor for Intelligent Packaging

2012 ◽  
Vol 18-19 ◽  
pp. 97-104 ◽  
Author(s):  
A.J. Martins ◽  
M. Benelmekki ◽  
V. Teixeira ◽  
P.J.G. Coutinho
Keyword(s):  
Aqueous Solution ◽  
Absorption Band ◽  
Reverse Micelle ◽  
Platinum Nanoparticles ◽  
Food Packaging ◽  
Thioglycolic Acid ◽  
Ph Sensor ◽  
Pt Nanoparticles ◽  
Nanoparticle Surface ◽  
Ph Variations

Pt nanoparticles were produced by reverse micelle templating using DTAB. The resulting nanoparticles showed sizes between 250nm and 500nm and formed clusters. Thioglycolic acid (TGA) was covalently attached to the nanoparticle surface as a stabilizer and as. The Pt nanoparticles were dispersed in water and the dependence of its absorvance on the pH of the solution was studied. The spectra showed surface plamon absorption band at 280nm and also red shifted bands that were attributed to clusters of nanoparticles. It was found that the fraction of cluster population depends on the pH of the aqueous solution and that the response of the Pt nanoparticles to pH variations has a memory effect (hysteresis). The possibility of using these Pt nanoparticles in smart labels for food packaging is outlined.

Novel far-visible and near-infrared pH probes based on styrylcyanine for imaging intracellular pH in live cells

2012 ◽  
Vol 48 (91) ◽  
pp. 11202 ◽  
Author(s):  
Li Fan ◽  
Yue-Jun Fu ◽  
Qiao-Ling Liu ◽  
Dong-Tao Lu ◽  
Chuan Dong ◽  
...  
Keyword(s):  
Intracellular Ph ◽  
Near Infrared ◽  
Live Cells ◽  
Ph Probes
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