Correlation of the stoichiometries of poly(ε-caprolactone) and α-cyclodextrin pseudorotaxanes with their solution rheology and the molecular orientation, crystallite size, and thermomechanical properties of their nanofibers

RSC Advances ◽  
2016 ◽  
Vol 6 (112) ◽  
pp. 111326-111336 ◽  
Author(s):  
Ganesh Narayanan ◽  
Ching-Chang Chung ◽  
Remil Aguda ◽  
Ramiz Boy ◽  
Matthew Hartman ◽  
...  
Keyword(s):  
Crystallite Size ◽  
Molecular Orientation ◽  
Biomedical Applications ◽  
Thermomechanical Properties ◽  
New Horizons ◽  
Biomedical Polymers ◽  
Solution Rheology

Pseudorotaxane nanofibers based on biomedical polymers, such as poly(ε-caprolactone) (PCL), and α-cyclodextrins (α-CD) open new horizons for a variety of biomedical applications.

scholarly journals CeO2 Nanoparticle-Containing Polymers for Biomedical Applications: A Review

Polymers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 924
Author(s):  
Alexander B. Shcherbakov ◽  
Vladimir V. Reukov ◽  
Alexander V. Yakimansky ◽  
Elena L. Krasnopeeva ◽  
Olga S. Ivanova ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Metal Oxide Nanoparticles ◽  
Polymeric Materials ◽  
Negative Effects ◽  
New Horizons ◽  
Beneficial Effects ◽  
Advanced Composite ◽  
Unique Material ◽  
Biomedical Polymers ◽  
Biomedical Potential

The development of advanced composite biomaterials combining the versatility and biodegradability of polymers and the unique characteristics of metal oxide nanoparticles unveils new horizons in emerging biomedical applications, including tissue regeneration, drug delivery and gene therapy, theranostics and medical imaging. Nanocrystalline cerium(IV) oxide, or nanoceria, stands out from a crowd of other metal oxides as being a truly unique material, showing great potential in biomedicine due to its low systemic toxicity and numerous beneficial effects on living systems. The combination of nanoceria with new generations of biomedical polymers, such as PolyHEMA (poly(2-hydroxyethyl methacrylate)-based hydrogels, electrospun nanofibrous polycaprolactone or natural-based chitosan or cellulose, helps to expand the prospective area of applications by facilitating their bioavailability and averting potential negative effects. This review describes recent advances in biomedical polymeric material practices, highlights up-to-the-minute cerium oxide nanoparticle applications, as well as polymer-nanoceria composites, and aims to address the question: how can nanoceria enhance the biomedical potential of modern polymeric materials?

scholarly journals Metal Nanozymes: New Horizons in Cellular Homeostasis Regulation

2021 ◽  
Vol 11 (19) ◽  
pp. 9019
Author(s):  
Hanna Lewandowska ◽  
Karolina Wójciuk ◽  
Urszula Karczmarczyk
Keyword(s):  
Biomedical Applications ◽  
Redox Status ◽  
Design Strategies ◽  
Future Directions ◽  
Cellular Homeostasis ◽  
Cellular Redox ◽  
New Horizons ◽  
Cellular Processes ◽  
Homeostasis Regulation ◽  
State Changes

Nanomaterials with enzyme-like activity (nanozymes) have found applications in various fields of medicine, industry, and environmental protection. This review discusses the use of nanozymes in the regulation of cellular homeostasis. We also review the latest biomedical applications of nanozymes related to their use in cellular redox status modification and detection. We present how nanozymes enable biomedical advances and demonstrate basic design strategies to improve diagnostic and therapeutic efficacy in various diseases. Finally, we discuss the current challenges and future directions for developing nanozymes for applications in the regulation of the redox-dependent cellular processes and detection in the cellular redox state changes.

Segmented imidazolium ionenes: Solution rheology, thermomechanical properties, and electrospinning

Polymer ◽  
2017 ◽  
Vol 114 ◽  
pp. 257-265 ◽  
Author(s):  
Christian Schreiner ◽  
Alexander T. Bridge ◽  
Matthew T. Hunley ◽  
Timothy E. Long ◽  
Matthew D. Green
Keyword(s):  
Thermomechanical Properties ◽  
Solution Rheology

scholarly journals One-Step Soft Chemical Synthesis of Magnetite Nanoparticles under Inert Gas Atmosphere. Magnetic Properties and In Vitro Study

Nanomaterials ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1500
Author(s):  
Laura Madalina Cursaru ◽  
Roxana Mioara Piticescu ◽  
Dumitru Valentin Dragut ◽  
Robert Morel ◽  
Caroline Thébault ◽  
...  
Keyword(s):  
Crystallite Size ◽  
Magnetite Nanoparticles ◽  
Biomedical Applications ◽  
Magnetic Measurements ◽  
Magnetic Moments ◽  
Inert Gas ◽  
Size Analysis ◽  
Hydrodynamic Diameter ◽  
Magnetic Cores ◽  
Gas Atmosphere

Iron oxide nanoparticles have received remarkable attention in different applications. For biomedical applications, they need to possess suitable core size, acceptable hydrodynamic diameter, high saturation magnetization, and reduced toxicity. Our aim is to control the synthesis parameters of nanostructured iron oxides in order to obtain magnetite nanoparticles in a single step, in environmentally friendly conditions, under inert gas atmosphere. The physical–chemical, structural, magnetic, and biocompatible properties of magnetite prepared by hydrothermal method in different temperature and pressure conditions have been explored. Magnetite formation has been proved by Fourier-transform infrared spectroscopy and X-ray diffraction characterization. It has been found that crystallite size increases with pressure and temperature increase, while hydrodynamic diameter is influenced by temperature. Magnetic measurements indicated that the magnetic core of particles synthesized at high temperature is larger, in accordance with the crystallite size analysis. Particles synthesized at 100 °C have nearly identical magnetic moments, at 20 × 103 μB, corresponding to magnetic cores of 10–11 nm, while the particles synthesized at 200 °C show slightly higher magnetic moments (25 × 103 μB) and larger magnetic cores (13 nm). Viability test results revealed that the particles show only minor intrinsic toxicity, meaning that these particles could be suited for biomedical applications.

scholarly journals Effect of Silica Addition on Mechanical Properties of Eggshell-Derived Hydroxyapatite

2021 ◽  
Vol 10 (2) ◽  
pp. 129-138
Author(s):  
. Fatma ◽  
. Desnelli ◽  
Fahma Riyanti ◽  
Mustafa Kamal ◽  
Muhammad Ramdan Abdul Mannan ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Compressive Strength ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Crystallite Size ◽  
Fourier Transform Infrared Spectroscopy ◽  
Biomedical Applications ◽  
X Ray Diffraction ◽  
X Ray ◽  
Silica Addition

Eggshell is a solid waste that is available in abundance but is being left unused. Eggshell containing calcium in a high amount. Calcium can be used as a precursor for hydroxyapatite (HAp). Modification of HAp with SiO2 is expected to improve its low mechanical properties for biomedical applications. In this study, HAp is synthesized from the eggshell. Then, it was modified by adding SiO2 utilizing the coprecipitation method with concentrations of 10%, 20%, 30%, and 40%, respectively. The HAp and HAp/SiO2 were characterized using; X-ray diffraction and Fourier transform infrared spectroscopy. The analysis HAp and HAp/SiO2 were density, compressive strength, and hardness. The best mechanical properties of HAp/SiO2 were characterized using SEM-EDS. The HAp were prepared successfully with a ratio of Ca/P was 1.673, close to the theoretical 1.67. The addition of SiO2 caused a decrease in crystallite size and density but increased compressive strength and hardness. The best mechanical properties of HAp/SiO2 were obtained with SiO2 of 30% and 40% with similar values.

scholarly journals Bioinspired by cell membranes: functional polymeric materials for biomedical applications

2020 ◽  
Vol 4 (3) ◽  
pp. 750-774 ◽  
Author(s):  
Xingyu Chen ◽  
Jianshu Li
Keyword(s):  
Biomedical Applications ◽  
Cell Membranes ◽  
Polymeric Materials ◽  
Biomedical Polymers

This review describes the functional biomedical polymers developed by the biomimetic/bioinspired strategies from various prototypes of cell membranes.

scholarly journals Nanozyme: new horizons for responsive biomedical applications

2019 ◽  
Vol 48 (14) ◽  
pp. 3683-3704 ◽  
Author(s):  
Dawei Jiang ◽  
Dalong Ni ◽  
Zachary T. Rosenkrans ◽  
Peng Huang ◽  
Xiyun Yan ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Artificial Enzymes ◽  
New Horizons

Nanozymes are nanomaterial-based artificial enzymes.

Aptamer functionalized nanomaterials for biomedical applications: Recent advances and new horizons

Nano Today ◽  
2021 ◽  
Vol 39 ◽  
pp. 101177
Author(s):  
Mansour Mahmoudpour ◽  
Shichao Ding ◽  
Zhaoyuan Lyu ◽  
Ghasem Ebrahimi ◽  
Dan Du ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
New Horizons ◽  
Recent Advances ◽  
Functionalized Nanomaterials

scholarly journals Near-Field Electrospinning and Melt Electrowriting of Biomedical Polymers—Progress and Limitations

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1097
Author(s):  
William E. King ◽  
Gary L. Bowlin
Keyword(s):  
Electric Field ◽  
Relative Motion ◽  
Biomedical Applications ◽  
Near Field ◽  
Biomedical Polymers ◽  
The Creation

Near-field electrospinning (NFES) and melt electrowriting (MEW) are the process of extruding a fiber due to the force exerted by an electric field and collecting the fiber before bending instabilities occur. When paired with precise relative motion between the polymer source and the collector, a fiber can be directly written as dictated by preprogrammed geometry. As a result, this precise fiber control results in another dimension of scaffold tailorability for biomedical applications. In this review, biomedically relevant polymers that to date have manufactured fibers by NFES/MEW are explored and the present limitations in direct fiber writing of standardization in published setup details, fiber write throughput, and increased ease in the creation of complex scaffold geometries are discussed.

Nanocomposited and Functionally Graded ZrN/HA Coatings on cp-Ti by RF Magnetron Sputtering

2012 ◽  
Vol 248 ◽  
pp. 37-42 ◽  
Author(s):  
A. Joseph Nathanael ◽  
Jun Hee Lee ◽  
Sun Ig Hong
Keyword(s):  
Crystallite Size ◽  
Biomedical Applications ◽  
Rf Magnetron Sputtering ◽  
Nanocomposite Coating ◽  
Functionally Graded ◽  
Nanocomposite Coatings ◽  
Hydroxyapatite Coatings ◽  
Graded Coatings ◽  
Functionally Graded Coatings ◽  
Cp Ti

Nanocomposited and Functionally graded (FG) ZrN/hydroxyapatite coatings with good mechanical strength and biocompatibility were prepared on cp-Ti substrate for biomedical applications and detailed analysis of the nanocomposite coatings for its structural, morphological, topographical and biocompatibility properties were carried out. Crystallite size of the coating for the functionally graded coatings was smaller compared to that of nanocomposite coatings. The arrangement of grains was observed to be denser in the FG coatings due to the decrease in the grain size. Hardness and modulus of FG coatings were observed to be greater than those of nanocomposite coating, which was attributed to the reduction in the crystallite size in FG coatings. Both ZrN/HA nanocomposite and functionally graded coatings was found to induce biomineralization formation, suggesting both are promising candidates for the future biomedical applications.

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