scholarly journals Rapid preparation of highly reliable PDMS double emulsion microfluidic devices

RSC Advances ◽  
2016 ◽  
Vol 6 (31) ◽  
pp. 25927-25933 ◽  
Author(s):  
Shunbo Li ◽  
Xiuqing Gong ◽  
Ciara S. Mc Nally ◽  
Muling Zeng ◽  
Thembaninkosi Gaule ◽  
...  
Keyword(s):  
Plasma Treatment ◽  
Reliable Method ◽  
Double Emulsion ◽  
Microfluidic Devices ◽  
Single Step ◽  
Rapid Preparation

This article presents a simple and highly reliable method for preparing PDMS microfluidic double emulsion devices that employs a single-step oxidative plasma treatment to both pattern the wettability of the microchannels and to bond the chips.

Microwave plasma treatment of polymer surface for irreversible sealing of microfluidic devices

Lab on a Chip ◽  
2005 ◽  
Vol 5 (10) ◽  
pp. 1173 ◽  
Author(s):  
Alex Y. N. Hui ◽  
Gang Wang ◽  
Bingcheng Lin ◽  
Wing-Tat Chan
Keyword(s):  
Plasma Treatment ◽  
Microwave Plasma ◽  
Polymer Surface ◽  
Microfluidic Devices

scholarly journals Heterogeneous Bonding of PMMA and Double-Sided Polished Silicon Wafers through H2O Plasma Treatment for Microfluidic Devices

Coatings ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 580
Author(s):  
Chao-Ching Chiang ◽  
Philip Nathaniel Immanuel ◽  
Yi-Hsiung Chiu ◽  
Song-Jeng Huang
Keyword(s):  
Plasma Treatment ◽  
Flow Rate ◽  
Gas Flow ◽  
Treatment Time ◽  
Optical Emission ◽  
Microfluidic Devices ◽  
Oh Radicals ◽  
Gas Flow Rate ◽  
Oh Groups ◽  
Plasma Treatment Time

In this work we report on a rapid, easy-to-operate, lossless, room temperature heterogeneous H2O plasma treatment process for the bonding of poly(methyl methacrylate) (PMMA) and double-sided polished (DSP) silicon substrates by for utilization in sandwich structured microfluidic devices. The heterogeneous bonding of the sandwich structure produced by the H2O plasma is analyzed, and the effect of heterogeneous bonding of free radicals and high charge electrons (e−) in the formed plasma which causes a passivation phenomenon during the bonding process investigated. The PMMA and silicon surface treatments were performed at a constant radio frequency (RF) power and H2O flow rate. Changing plasma treatment time and powers for both processes were investigated during the experiments. The gas flow rate was controlled to cause ionization of plasma and the dissociation of water vapor from hydrogen (H) atoms and hydroxyl (OH) bonds, as confirmed by optical emission spectroscopy (OES). The OES results show the relative intensity peaks emitted by the OH radicals, H and oxygen (O). The free energy is proportional to the plasma treatment power and gas flow rate with H bonds forming between the adsorbed H2O and OH groups. The gas density generated saturated bonds at the interface, and the discharge energy that strengthened the OH-e− bonds. This method provides an ideal heterogeneous bonding technique which can be used to manufacture new types of microfluidic devices.

scholarly journals Rapid and Inexpensive Fabrication of Multi-Depth Microfluidic Device using High-Resolution LCD Stereolithographic 3D Printing

2019 ◽  
Vol 3 (1) ◽  
pp. 26 ◽  
Author(s):  
Mohamed Mohamed ◽  
Hitendra Kumar ◽  
Zongjie Wang ◽  
Nicholas Martin ◽  
Barry Mills ◽  
...  
Keyword(s):  
High Resolution ◽  
3D Printing ◽  
Soft Lithography ◽  
Liquid Crystal Display ◽  
Three Dimensional ◽  
Microfluidic Devices ◽  
Single Step ◽  
Droplet Generator ◽  
Rapid Fabrication ◽  
Printing System

With the dramatic increment of complexity, more microfluidic devices require 3D structures, such as multi-depth and -layer channels. The traditional multi-step photolithography is time-consuming and labor-intensive and also requires precise alignment during the fabrication of microfluidic devices. Here, we present an inexpensive, single-step, and rapid fabrication method for multi-depth microfluidic devices using a high-resolution liquid crystal display (LCD) stereolithographic (SLA) three-dimensional (3D) printing system. With the pixel size down to 47.25 μm, the feature resolutions in the horizontal and vertical directions are 150 μm and 50 μm, respectively. The multi-depth molds were successfully printed at the same time and the multi-depth features were transferred properly to the polydimethylsiloxane (PDMS) having multi-depth channels via soft lithography. A flow-focusing droplet generator with a multi-depth channel was fabricated using the presented 3D printing method. Experimental results show that the multi-depth channel could manipulate the morphology and size of droplets, which is desired for many engineering applications. Taken together, LCD SLA 3D printing is an excellent alternative method to the multi-step photolithography for the fabrication of multi-depth microfluidic devices. Taking the advantages of its controllability, cost-effectiveness, and acceptable resolution, LCD SLA 3D printing can have a great potential to fabricate 3D microfluidic devices.

Low temperature and deformation-free bonding of PMMA microfluidic devices with stable hydrophilicity via oxygen plasma treatment and PVA coating

RSC Advances ◽  
2015 ◽  
Vol 5 (11) ◽  
pp. 8377-8388 ◽  
Author(s):  
H. Yu ◽  
Z. Z. Chong ◽  
S. B. Tor ◽  
E. Liu ◽  
N. H. Loh
Keyword(s):  
Low Temperature ◽  
Plasma Treatment ◽  
Oxygen Plasma ◽  
Microfluidic Devices ◽  
Oxygen Plasma Treatment ◽  
Bonding Method

A deformation-free bonding method with stable hydrophilicity in PMMA devices has been proposed through oxygen plasma treatment and PVA coating.

scholarly journals Use of Multi-Hollow Polyester Particles as Opacifying Agent for Injection-Molded Polyethylene

Polymers ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1331
Author(s):  
João F. A. Silva ◽  
Tânia M. T. Carvalho ◽  
Margarida L. Almeida ◽  
Paula Pereira ◽  
Helena Sousa ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Double Emulsion ◽  
Single Step ◽  
Melt Processing ◽  
Light Refraction ◽  
White Pigment ◽  
Titanium Dioxide Content ◽  
Similar Strategy ◽  
Emulsion Process ◽  
Injection Molded

Titanium dioxide is considered the most efficient white pigment for opacification of thermoplastics. However, its high cost, combined with strong price oscillations due to production bottlenecks, has been driving the industry towards alternatives that might allow reducing the titanium dioxide content, while maintaining the product’s opacity. A strategy commonly used in waterborne paints consists in adding hollow polymer particles to the formulation, therefore achieving opacification due to light refraction at the air/polymer interface. In the current work, we show preliminary results that indicate that a similar strategy can be followed for thermoplastics opacification, as long as thermoset particles are used, in order to ensure preservation of the hollow geometry during melt-processing. Multi-vesiculated crosslinked styrene–polyester particles, produced by a single-step double emulsion process, are used. Evidence of synergic interaction between the multi-hollow particles and titanium dioxide has been found.

scholarly journals Three-Dimensional Printing Based Hybrid Manufacturing of Microfluidic Devices

2015 ◽  
Vol 6 (2) ◽  
Author(s):  
Yunus Alapan ◽  
Muhammad Noman Hasan ◽  
Richang Shen ◽  
Umut A. Gurkan
Keyword(s):  
3D Printing ◽  
Microfluidic Device ◽  
High Surface ◽  
Three Dimensional ◽  
Microfluidic Devices ◽  
Single Step ◽  
Device Fabrication ◽  
Hybrid Manufacturing ◽  
Fabrication Method ◽  
Design Complexity

Microfluidic platforms offer revolutionary and practical solutions to challenging problems in biology and medicine. Even though traditional micro/nanofabrication technologies expedited the emergence of the microfluidics field, recent advances in advanced additive manufacturing hold significant potential for single-step, stand-alone microfluidic device fabrication. One such technology, which holds a significant promise for next generation microsystem fabrication is three-dimensional (3D) printing. Presently, building 3D printed stand-alone microfluidic devices with fully embedded microchannels for applications in biology and medicine has the following challenges: (i) limitations in achievable design complexity, (ii) need for a wider variety of transparent materials, (iii) limited z-resolution, (iv) absence of extremely smooth surface finish, and (v) limitations in precision fabrication of hollow and void sections with extremely high surface area to volume ratio. We developed a new way to fabricate stand-alone microfluidic devices with integrated manifolds and embedded microchannels by utilizing a 3D printing and laser micromachined lamination based hybrid manufacturing approach. In this new fabrication method, we exploit the minimized fabrication steps enabled by 3D printing, and reduced assembly complexities facilitated by laser micromachined lamination method. The new hybrid fabrication method enables key features for advanced microfluidic system architecture: (i) increased design complexity in 3D, (ii) improved control over microflow behavior in all three directions and in multiple layers, (iii) transverse multilayer flow and precisely integrated flow distribution, and (iv) enhanced transparency for high resolution imaging and analysis. Hybrid manufacturing approaches hold great potential in advancing microfluidic device fabrication in terms of standardization, fast production, and user-independent manufacturing.

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