pH-Triggered copolymer micelles as drug nanocarriers for intracellular delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (35) ◽  
pp. 29149-29158 ◽  
Author(s):  
Weiju Hao ◽  
Danyang Liu ◽  
Yazhuo Shang ◽  
Junqi Zhang ◽  
Shouhong Xu ◽  
...  
Keyword(s):  
Polymeric Micelles ◽  
Intracellular Delivery ◽  
Ph Sensitive ◽  
High Loading ◽  
Loading Capacity ◽  
Triggered Release ◽  
Copolymer Micelles ◽  
Drug Nanocarriers

We prepared pH-sensitive polymeric micelles which were used as nano-carriers and exhibited a high loading capacity and pH-triggered release of DOX.

Real time monitoring of peptide delivery in vitro using high payload pH responsive nanogels

2020 ◽  
Vol 11 (2) ◽  
pp. 425-432 ◽  
Author(s):  
Shegufta Farazi ◽  
Fan Chen ◽  
Henry Foster ◽  
Raelene Boquiren ◽  
Shelli R. McAlpine ◽  
...  
Keyword(s):  
Real Time ◽  
Intracellular Delivery ◽  
Peptide Delivery ◽  
High Loading ◽  
Loading Capacity ◽  
Ph Responsive ◽  
Real Time Monitoring ◽  
High Payload

A pH responsive pMAA nanogel that demonstrates high loading capacity and rapid intracellular delivery of hydrophilic peptides.

Development of propolis-loaded block copolymer micelles of superior structural stability and high loading capacity

Polymer ◽  
2017 ◽  
Vol 125 ◽  
pp. 102-109 ◽  
Author(s):  
Petar D. Petrov ◽  
Georgy Grancharov ◽  
Valeria Gancheva ◽  
Boryana Trusheva ◽  
Vassya Bankova ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Structural Stability ◽  
High Loading ◽  
Loading Capacity ◽  
Block Copolymer Micelles ◽  
Copolymer Micelles

Tumor extracellular pH-sensitive polymeric nanocarrier-grafted platinum(iv) prodrugs for improved intracellular delivery and cytosolic reductive-triggered release

2020 ◽  
Vol 11 (12) ◽  
pp. 2212-2221 ◽  
Author(s):  
Sheng-Qi Chen ◽  
Gang Song ◽  
Chen He ◽  
Mei Hou ◽  
Wei-Dong He ◽  
...  
Keyword(s):  
Drug Release ◽  
Tumor Cells ◽  
Intracellular Delivery ◽  
Ph Sensitive ◽  
Extracellular Ph ◽  
Triggered Release ◽  
Triggered Drug Release ◽  
Release Strategy ◽  
Polymeric Nanocarrier

Extracellular pH-sensitive Pt(iv)-based nanodrugs enable preferential toxicity to tumor cells via a selectively endocytosed and triggered drug release strategy.

scholarly journals Effects of morphology and pore size of mesoporous silicas on the efficiency of an immobilized enzyme

RSC Advances ◽  
2021 ◽  
Vol 11 (17) ◽  
pp. 10010-10017
Author(s):  
Ping-Chung Kuo ◽  
Zhi-Xun Lin ◽  
Tzi-Yi Wu ◽  
Chun-Han Hsu ◽  
Hong-Ping Lin ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Mesoporous Silica ◽  
Pore Size ◽  
Immobilized Enzyme ◽  
Mesoporous Silicas ◽  
High Loading ◽  
Loading Capacity ◽  
Silica Films

Mesoporous silica films were used as supports with high loading capacity and enzyme activity.

Reversibly cross-linked poly(ethylene glycol)–poly(amino acid)s copolymer micelles: a promising approach to overcome the extracellular stability versus intracellular drug release challenge

RSC Advances ◽  
2015 ◽  
Vol 5 (26) ◽  
pp. 20025-20034 ◽  
Author(s):  
Yuling Li ◽  
Sai Wang ◽  
Dandan Zhu ◽  
Yuling Shen ◽  
Baixiang Du ◽  
...  
Keyword(s):  
Amino Acid ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Lipoic Acid ◽  
Triblock Copolymer ◽  
Intracellular Delivery ◽  
Poly Ethylene Glycol ◽  
Copolymer Micelles ◽  
Poly Ethylene ◽  
Copolymer Poly

Reversibly shell cross-linked micelles based on a lipoic acid (LA) decorated triblock copolymer poly(ethylene glycol)-b-poly(γ-benzyl-l-glutamate)-b-poly(l-phenylalanine) have been developed for efficient intracellular delivery of DOX.

Preparation of porous cellulose 3,5-dimethylphenylcarbamate hybrid organosilica particles for chromatographic applications

2015 ◽  
Vol 3 (4) ◽  
pp. 620-628 ◽  
Author(s):  
Xilun Weng ◽  
Zongbi Bao ◽  
Zhiguo Zhang ◽  
Baogen Su ◽  
Huabin Xing ◽  
...  
Keyword(s):  
Silica Particles ◽  
Chiral Selector ◽  
High Loading ◽  
Loading Capacity ◽  
Functionalized Silica

Organic–inorganic hybrids incorporating cellulose tris(3,5-dimethylphenylcarbamate) (CDMPC)-functionalized silica particles can exhibit a high loading capacity with high loadings of the chiral selector.

Design and synthesis of periodic mesoporous organosilica materials with a multi-compartment structure

RSC Advances ◽  
2015 ◽  
Vol 5 (109) ◽  
pp. 89397-89406 ◽  
Author(s):  
Chun Xiang Cynthia Lin ◽  
Siddharth Jambhrunkar ◽  
Pei Yuan ◽  
Chun Hui Clayton Zhou ◽  
George Xiu Song Zhao
Keyword(s):  
Anticancer Drug ◽  
Release Rate ◽  
Slow Release ◽  
Drug Carrier ◽  
High Loading ◽  
Loading Capacity ◽  
Periodic Mesoporous Organosilica ◽  
Design And Synthesis ◽  
Mesoporous Organosilica ◽  
Organosilica Materials

Multi-compartment periodic mesoporous organosilica materials show desirable properties as anticancer drug carrier with high loading capacity and slow release rate.

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