Design, synthesis and biological evaluation of pyrazoline nucleus based homoleptic Ru(iii) compounds

MedChemComm ◽  
2016 ◽  
Vol 7 (7) ◽  
pp. 1367-1380 ◽  
Author(s):  
Jugal V. Mehta ◽  
Sanjay B. Gajera ◽  
Mohan N. Patel
Keyword(s):  
Molecular Docking ◽  
Dna Binding ◽  
Dna Cleavage ◽  
Biological Evaluation ◽  
Biological Applications ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

Biological applications of homoleptic Ru(iii) compounds towards molecular docking, DNA-binding and DNA cleavage.

Half-sandwich iridiumIII complexes with pyrazole-substituted heterocyclic frameworks and their biological applications

2016 ◽  
Vol 40 (12) ◽  
pp. 9968-9980 ◽  
Author(s):  
Sanjay B. Gajera ◽  
Jugal V. Mehta ◽  
Parth Thakor ◽  
Vasudev R. Thakkar ◽  
Piyushkumar C. Chudasama ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Dna Binding ◽  
Metal Complexes ◽  
Antiproliferative Activity ◽  
Dna Cleavage ◽  
Biological Function ◽  
Biological Applications ◽  
Half Sandwich

Enhancement in the biological function, i.e., DNA binding, molecular docking, antiproliferative activity and DNA cleavage, of metal complexes as compared to free ligands is observed.

Design, synthesis and biological evaluation of Pontin ATPase inhibitors through a molecular docking approach

2014 ◽  
Vol 24 (11) ◽  
pp. 2512-2516 ◽  
Author(s):  
Judith Elkaim ◽  
Marc Lamblin ◽  
Michel Laguerre ◽  
Jean Rosenbaum ◽  
Patrick Lestienne ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Atpase Inhibitors ◽  
Docking Approach ◽  
Synthesis And Biological Evaluation

scholarly journals The structure-based design, synthesis and biological evaluation of DNA-binding bisintercalating bisanthrapyrazole anticancer compounds

2008 ◽  
Vol 16 (7) ◽  
pp. 3959-3968 ◽  
Author(s):  
Brian B. Hasinoff ◽  
Hong Liang ◽  
Xing Wu ◽  
Lynn J. Guziec ◽  
Frank S. Guziec Jr. ◽  
...  
Keyword(s):  
Dna Binding ◽  
Biological Evaluation ◽  
Anticancer Compounds ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation
Sign in / Sign up

Export Citation Format

Share Document