Half-sandwich iridiumIII complexes with pyrazole-substituted heterocyclic frameworks and their biological applications

2016 ◽  
Vol 40 (12) ◽  
pp. 9968-9980 ◽  
Author(s):  
Sanjay B. Gajera ◽  
Jugal V. Mehta ◽  
Parth Thakor ◽  
Vasudev R. Thakkar ◽  
Piyushkumar C. Chudasama ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Dna Binding ◽  
Metal Complexes ◽  
Antiproliferative Activity ◽  
Dna Cleavage ◽  
Biological Function ◽  
Biological Applications ◽  
Half Sandwich

Enhancement in the biological function, i.e., DNA binding, molecular docking, antiproliferative activity and DNA cleavage, of metal complexes as compared to free ligands is observed.

Novel Schiff base metal complexes: synthesis, characterization, DNA binding, DNA cleavage and molecular docking studies

2018 ◽  
Vol 15 (6) ◽  
pp. 1377-1389 ◽  
Author(s):  
Mayuri Bheemarasetti ◽  
Kavitha Palakuri ◽  
Shweta Raj ◽  
Prakash Saudagar ◽  
Durgaiah Gandamalla ◽  
...  
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Dna Binding ◽  
Metal Complexes ◽  
Base Metal ◽  
Dna Cleavage ◽  
Docking Studies ◽  
Molecular Docking Studies ◽  
Schiff Base Metal Complexes

Design, synthesis and biological evaluation of pyrazoline nucleus based homoleptic Ru(iii) compounds

MedChemComm ◽  
2016 ◽  
Vol 7 (7) ◽  
pp. 1367-1380 ◽  
Author(s):  
Jugal V. Mehta ◽  
Sanjay B. Gajera ◽  
Mohan N. Patel
Keyword(s):  
Molecular Docking ◽  
Dna Binding ◽  
Dna Cleavage ◽  
Biological Evaluation ◽  
Biological Applications ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

Biological applications of homoleptic Ru(iii) compounds towards molecular docking, DNA-binding and DNA cleavage.

New binuclear Ni(ii) metallates containing ONS chelators: synthesis, characterisation, DNA binding, DNA cleavage, protein binding, antioxidant activity, antimicrobial and in vitro cytotoxicity

2017 ◽  
Vol 41 (7) ◽  
pp. 2543-2560 ◽  
Author(s):  
G. Kalaiarasi ◽  
Ruchi Jain ◽  
H. Puschman ◽  
S. Poorna Chandrika ◽  
K. Preethi ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Dna Binding ◽  
Protein Binding ◽  
Hela Cell ◽  
Antiproliferative Activity ◽  
Dna Cleavage ◽  
In Vitro Cytotoxicity ◽  
Hela Cell Lines ◽  
Mcf 7

Four new binuclear nickel(ii) metallates showed promising antiproliferative activity against MCF-7 and HeLa cell lines and were much less toxic against HaCaT.

scholarly journals Synthesis of novel calix[4]arene p-benzazole derivatives and investigation of their DNA binding and cleavage activities with molecular docking and experimental studies

RSC Advances ◽  
2020 ◽  
Vol 10 (63) ◽  
pp. 38695-38708
Author(s):  
Seyda Cigdem Ozkan ◽  
Fatma Aksakal ◽  
Aydan Yilmaz
Keyword(s):  
Molecular Docking ◽  
Dna Binding ◽  
Dna Cleavage ◽  
Experimental Studies ◽  
Binding Properties ◽  
Dna Binding And Cleavage

In this study, p-benzazole-derived calix[4]arene compounds with aromatic structures are synthesized and their DNA cleavage/binding properties are investigated.

scholarly journals Design, synthesis, and pharmacology of some oxadiazole and hydroxypyrazoline hybrids bearing thiazoyl scaffold: antiproliferative activity, molecular docking and DNA binding studies

Heliyon ◽  
2019 ◽  
Vol 5 (2) ◽  
pp. e01255 ◽  
Author(s):  
Rangappa Santosh ◽  
Ashwini Prabhu ◽  
Mukunthan K. Selvam ◽  
Panchangam M. Krishna ◽  
Gundibasappa K. Nagaraja ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Dna Binding ◽  
Antiproliferative Activity ◽  
Binding Studies ◽  
Design Synthesis ◽  
Dna Binding Studies
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