scholarly journals Oligonucleotide-based label-free detection with optical microresonators: strategies and challenges

Lab on a Chip ◽  
2016 ◽  
Vol 16 (14) ◽  
pp. 2572-2595 ◽  
Author(s):  
Pelin Toren ◽  
Erol Ozgur ◽  
Mehmet Bayindir
Keyword(s):  
Lab On A Chip ◽  
Whispering Gallery Mode ◽  
Optical Biosensors ◽  
Label Free ◽  
Optical Microresonators ◽  
Whispering Gallery ◽  
Label Free Detection

This review targets diversified oligonucleotide-based biodetection techniques, focusing on the use of microresonators of whispering gallery mode (WGM) type as optical biosensors mostly integrated with lab-on-a-chip systems.

scholarly journals Direct writing of optical microresonators in a lab-on-a-chip for label-free biosensing

Lab on a Chip ◽  
2019 ◽  
Vol 19 (11) ◽  
pp. 1985-1990 ◽  
Author(s):  
L. Kelemen ◽  
E. Lepera ◽  
B. Horváth ◽  
P. Ormos ◽  
R. Osellame ◽  
...  
Keyword(s):  
Lab On A Chip ◽  
Whispering Gallery Mode ◽  
Label Free ◽  
Direct Writing ◽  
Laser Fabrication ◽  
Optical Microresonators ◽  
Whispering Gallery ◽  
Whispering Gallery Mode Resonator ◽  
Biomolecule Sensing ◽  
Mode Resonator

Hybrid femtosecond laser fabrication of a glass lab-on-a-chip, with an integrated whispering gallery mode resonator, for label-free biomolecule sensing.

Integration of digital microfluidics with whispering-gallery mode sensors for label-free detection of biomolecules

Lab on a Chip ◽  
2017 ◽  
Vol 17 (10) ◽  
pp. 1740-1748 ◽  
Author(s):  
Sentayehu F. Wondimu ◽  
Sebastian von der Ecken ◽  
Ralf Ahrens ◽  
Wolfgang Freude ◽  
Andreas E. Guber ◽  
...  
Keyword(s):  
Refractive Index ◽  
Digital Microfluidics ◽  
Whispering Gallery Mode ◽  
Label Free ◽  
Biosensor Arrays ◽  
Whispering Gallery ◽  
Label Free Detection ◽  
Detection Of Biomolecules

WGM biosensor arrays are integrated with a DMF system. The viability of the system is demonstrated by refractive-index and biosensing experiments.

Optical whispering gallery mode resonators for label-free detection of water contaminants

2020 ◽  
Vol 126 ◽  
pp. 115856 ◽  
Author(s):  
Simone Berneschi ◽  
Francesca Bettazzi ◽  
Ambra Giannetti ◽  
Francesco Baldini ◽  
Gualtiero Nunzi Conti ◽  
...  
Keyword(s):  
Whispering Gallery Mode ◽  
Label Free ◽  
Water Contaminants ◽  
Whispering Gallery ◽  
Label Free Detection

scholarly journals Review of biosensing with whispering-gallery mode lasers

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Nikita Toropov ◽  
Gema Cabello ◽  
Mariana P. Serrano ◽  
Rithvik R. Gutha ◽  
Matías Rafti ◽  
...  
Keyword(s):  
Biological Samples ◽  
Whispering Gallery Mode ◽  
Photonic Devices ◽  
Whispering Gallery Modes ◽  
Label Free ◽  
Virus Particles ◽  
Whispering Gallery ◽  
Label Free Detection ◽  
Basic Concepts ◽  
Wgm Resonators

AbstractLasers are the pillars of modern optics and sensing. Microlasers based on whispering-gallery modes (WGMs) are miniature in size and have excellent lasing characteristics suitable for biosensing. WGM lasers have been used for label-free detection of single virus particles, detection of molecular electrostatic changes at biointerfaces, and barcode-type live-cell tagging and tracking. The most recent advances in biosensing with WGM microlasers are described in this review. We cover the basic concepts of WGM resonators, the integration of gain media into various active WGM sensors and devices, and the cutting-edge advances in photonic devices for micro- and nanoprobing of biological samples that can be integrated with WGM lasers.

The whispering gallery mode biosensor: label-free detection from virus to single protein

2014 ◽  
Author(s):  
S. Holler ◽  
V. R. Dantham ◽  
D. Keng ◽  
V. Kolchenko ◽  
S. Arnold ◽  
...  
Keyword(s):  
Whispering Gallery Mode ◽  
Label Free ◽  
Whispering Gallery ◽  
Label Free Detection ◽  
Single Protein
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