Variable coordination and C–S bond cleavage activity of N-substituted imidazolidine-2-thiones towards copper: synthesis, spectroscopy, structures, ESI-mass and antimicrobial studies

2017 ◽  
Vol 46 (4) ◽  
pp. 1324-1339 ◽  
Author(s):  
Jaspreet K. Aulakh ◽  
Tarlok S. Lobana ◽  
Henna Sood ◽  
Daljit S. Arora ◽  
Isabel Garcia-Santos ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Bond Cleavage ◽  
Living Cells ◽  
Cleavage Activity ◽  
Antimicrobial Studies ◽  
Variable Coordination

N-substituted imidazoldine-2-thiones with copper(i) halides have shown variable nuclearity, C–S bond cleavage, antimicrobial activity and non-toxicity in some cases to living cells.

scholarly journals Correction: Variable coordination and C–S bond cleavage activity of N-substituted imidazolidine-2-thiones towards copper: synthesis, spectroscopy, structures, ESI-mass and antimicrobial studies

2017 ◽  
Vol 46 (43) ◽  
pp. 15138-15138
Author(s):  
Jaspreet K. Aulakh ◽  
Tarlok S. Lobana ◽  
Henna Sood ◽  
Daljit S. Arora ◽  
Isabel Garcia-Santos ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Dalton Trans ◽  
Cleavage Activity ◽  
Antimicrobial Studies ◽  
Variable Coordination

Correction for ‘Variable coordination and C–S bond cleavage activity of N-substituted imidazolidine-2-thiones towards copper: synthesis, spectroscopy, structures, ESI-mass and antimicrobial studies’ by Jaspreet K. Aulakh, et al., Dalton Trans., 2017, 46, 1324–1339.

Expansion of Nanosized MgSiO3/Chitosan Nanocomposite Structural and Spectroscopic for Loading Velosef by Nanomaterial Intervention

2021 ◽  
Author(s):  
amal aboelnaga ◽  
talaat Meaz ◽  
amany M elnahrawy
Keyword(s):  
Antimicrobial Activity ◽  
High Performance ◽  
Sol Gel ◽  
Polymerization Process ◽  
Absorption Bands ◽  
Structural Morphology ◽  
Crystallinity Degree ◽  
Chitosan Matrix ◽  
Antimicrobial Studies ◽  
Sol Gel Process

Abstract The aim of this study is to investigate the effect of different doses of Velosef in magnesium silica/chitosan nanocomposite in terms of structural, morphology, optical properties, and bioactivity. Loading Velosef in fine-sized magnesium silica/chitosan is an efficient engineering approach for drug delivery. The sol-gel process was used to prepare magnesium silica fine-sized before being blended into chitosan matrix, which acts as a potential morphogenetic biomaterial. The Velosef/magnesium silica/chitosan nanocomposites were characterized by XRD, TEM, SEM, FTIR, UV-absorption, and antimicrobial studies. The XRD was characteristic of the crystallinity degree of the MgO-SiO2/chitosan/Velosef nanocomposites with three maximum peaks at 26.37°, 33.34o, 36.9°. FTIR results indicated the structural change occurred with the Velosef sol-gel polymerization process. UV-absorbance reveals that the MgO-SiO2/chitosan nanocomposite appeared a high performance for loading Velosef at two absorption bands at 253 and 347 nm. The MgO-SiO2/Chitosan/Velosef nanocomposites showed considerable antimicrobial activity in opposition to the tested representative microorganisms. The maximum antimicrobial activity was obtained with MgO-SiO2/Chitosan against both Escherichia coli and Candida albicans (37 mm), while the minimum antimicrobial activity (30 mm) was recorded against B. mycoides and E. coli with control.

scholarly journals Synthesis, Characterization and Antimicrobial Studies of N1-[(1E)-1-(2-Hydroxyphenyl) ethylidene]-2-oxo-2H-chromene-3-carbohydrazide and its Metal Complexes

2009 ◽  
Vol 6 (3) ◽  
pp. 615-624 ◽  
Author(s):  
K. Siddappa ◽  
K. Mallikarjun ◽  
Tukaram Reddy ◽  
M. Mallikarjun ◽  
C. V. Reddy ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Magnetic Susceptibility ◽  
Schiff Base ◽  
Metal Complexes ◽  
Molar Conductance ◽  
Tetrahedral Geometry ◽  
H Nmr ◽  
Antimicrobial Studies ◽  
Mononuclear Complexes ◽  
Uv Visible

A new complexes of the type ML, MʹL and M″L [where M=Cu(II), Co(II), Ni(II) and Mn(II), Mʹ=Fe(III) and M″=Zn(II), Cd(II) and Hg(II) and L=N1-[(1E)-1-(2-hydroxyphenyl)ethylidene]-2-oxo-2H-chromene- 3-carbohydrazide (HL)] Schiff base have been synthesized and characterized by elemental analysis, magnetic susceptibility, molar conductance, IR,1H NMR, UV-Visible and ESR data. The studies indicate the HL acts as doubly monodentate bridge for metal ions and form mononuclear complexes. The complexes Ni(II), Co(II), Cu(II) Mn(II) and Fe(III) complexes are found to be octahedral, where as Zn(II), Cd(II) and Hg(II) complexes are four coordinated with tetrahedral geometry. The synthesized ligand and its metal complexes were screened for their antimicrobial activity.

scholarly journals Synthesis and Antimicrobial Studies of a New Series of Bis-Heterocycles

2008 ◽  
Vol 5 (2) ◽  
pp. 370-376 ◽  
Author(s):  
B. Jayashankara ◽  
K.M. Lokanatha Rai
Keyword(s):  
Antimicrobial Activity ◽  
Antimicrobial Studies ◽  
Elemental Analyses

Series of novel bis-heterocycles bearing isoxazoline and imidazole moieties have been synthesizedvia1,3-dipolarcycloaddition reactions.1HNMR,13CNMR, IR and elemental analyses characterized the newly synthesized compounds. All the synthesized compounds were evaluated for their antimicrobial activity and were compared with the standard drugs. The compounds demonstrated potent to weak antimicrobial activity.

scholarly journals Synthesis, Characterization and Antimicrobial Studies of 3-[(2-Hydroxy-quinolin-3-ylmethylene)-amino]-2-phenyl-3H-quinazolin-4-one and its Metal(II) Complexes

2008 ◽  
Vol 5 (1) ◽  
pp. 155-162 ◽  
Author(s):  
K. Siddappa ◽  
Tukaram Reddy ◽  
M. Mallikarjun ◽  
C. V. Reddy
Keyword(s):  
Antimicrobial Activity ◽  
Magnetic Susceptibility ◽  
Schiff Base ◽  
Elemental Analysis ◽  
Molar Conductance ◽  
Tetrahedral Geometry ◽  
H Nmr ◽  
Antimicrobial Studies ◽  
Mononuclear Complexes ◽  
Uv Visible

A new complexes of the type ML2 and M′L [where M=Cu(II), Co(II), and Ni(II) and M′= Zn(II), Cd(II) and Hg(II)]. L = 3-[(2-hydroxy-quinolin-3-ylmethylene)-amino]-2-phenyl-3H-quinazolin-4-one, (HQMAPQ) Schiff base have been synthesized and characterized by elemental analysis, magnetic susceptibility, molar conductance, IR,1H NMR, UV-Visible and ESR data. The studies indicate the HQMAPQ acts as doubly monodentate bridge for metal(II) ions and form mononuclear complexes. The complexes Ni(II), Co(II) and Cu(II) complexes are found to be octahedral, where as Zn(II), Cd(II) and Hg(II) complexes are four coordinated with tetrahedral geometry. The synthesized ligand and its metal(II) complexes were screened for their antimicrobial activity.

scholarly journals Microwave Assisted One Pot Synthesis of Tetrazole Based 3-hydroxy-4H-chromen-4-ones by modified Algar-Flynn-Oyamada reaction and their Antimicrobial activity

2019 ◽  
Vol 63 (4) ◽  
Author(s):  
ASHOK DONGAMANTI ◽  
Nagaraju Nalaparaju ◽  
Sarasija Madderla ◽  
Vijaya Lakshmi Bommidi
Keyword(s):  
Escherichia Coli ◽  
Antimicrobial Activity ◽  
Klebsiella Pneumonia ◽  
Good Activity ◽  
One Pot ◽  
Microwave Assisted ◽  
One Pot Synthesis ◽  
Antimicrobial Studies ◽  
The One

In the present work, we report the one pot synthesis of tetrazole based 3-hydroxy-4H-chromen-4-ones 3(a-g) from  4-(1H-tetrazol-5-yl)benzaldehyde and 2-hydroxy acetophenone using KOH and H2O2 by modified Algar-Flynn-Oyamada reaction under conventional and microwave irradiation conditions. In this technique, flavonols are synthesized without isolating chalcones, in good yields. All the synthesized compounds were characterized by IR, NMR, MS and elemental. All newly synthesized compounds were screened for their in-vitro antimicrobial activity against strains such as Staphylococcus aurous, Bacillus subtilis, Klebsiella pneumonia, Escherichia coli, Aspergillus Niger, Aspergillus flavus, and Fusarium oxysporum. The results of antimicrobial studies revealed that most of the compounds exhibit good activity.

scholarly journals Selective catecholamine detection in living cells by a copper-mediated oxidative bond cleavage

2019 ◽  
Vol 10 (37) ◽  
pp. 8519-8526 ◽  
Author(s):  
Ka Yan Tong ◽  
Jia Zhao ◽  
Chun-Wai Tse ◽  
Pui-Ki Wan ◽  
Jianhui Rong ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Bond Cleavage ◽  
Living Cells ◽  
Turn On

A copper-mediated oxidative bond cleavage induced by catecholamines is developed into a turn-on fluorescent probe for imaging of the neurotransmitter in living cells.

scholarly journals Antibacterial Activity of Amidodithiophosphonato Nickel(II) Complexes: An Experimental and Theoretical Approach

Molecules ◽  
2020 ◽  
Vol 25 (9) ◽  
pp. 2052 ◽  
Author(s):  
Enrico Podda ◽  
Massimiliano Arca ◽  
Giulia Atzeni ◽  
Simon J. Coles ◽  
Antonella Ibba ◽  
...  
Keyword(s):  
Density Functional Theory ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Dft Calculations ◽  
Density Functional ◽  
Bond Cleavage ◽  
Nickel Complexes ◽  
Functional Theory ◽  
Gram Negative

The reactions of 2,4-bis(4-methoxyphenyl)-1,3-dithio-2,4-diphosphetane-2,4-disulfide (Lawesson’s Reagent, LR) with benzylamine (BzNH2) and 4-phenylbutylamine (PhBuNH2) yield benzylammonium P-(4-methoxyphenyl)-N-benzyl-amidodithiophosphonate (BzNH3)(BzNH-adtp) and 4-phenylbutylammonium P-(4-methoxyphenyl)-N-(4-phenylbutyl)-amidodithiophosphonate (PhBuNH3)(PhBuNH-adtp). The relevant nickel complexes [Ni(BzNH-adtp)2] and [Ni(PhBuNH-adtp)2] and the corresponding hydrolysed derivatives (BzNH3)2[Ni(dtp)2] and (PhBuNH3)2[Ni(dtp)2] were prepared and fully characterized. The antimicrobial activity of the aforementioned amidodithiophosphonates against a set of Gram-positive and Gram-negative pathogen bacteria was evaluated, and [Ni(BzNH-adtp)2] and [Ni(PhBuNH-adtp)2] showed antiproliferative activity towards Staphylococcus aureus and Staphylococcus haemolyticus strains. density functional theory (DFT) calculations were performed to shed some light on the activity of reported compounds related to their tendency towards P–N bond cleavage.

Sensitive Near-Infrared Fluorescent Probes for Thiols Based on SeN Bond Cleavage: Imaging in Living Cells and Tissues

2012 ◽  
Vol 18 (36) ◽  
pp. 11343-11349 ◽  
Author(s):  
Rui Wang ◽  
Lingxin Chen ◽  
Ping Liu ◽  
Qin Zhang ◽  
Yunqing Wang
Keyword(s):  
Fluorescent Probes ◽  
Near Infrared ◽  
Bond Cleavage ◽  
Living Cells
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