Programmable DNA triple-helix molecular switch in biosensing applications: from in homogenous solutions to in living cells

2017 ◽  
Vol 53 (16) ◽  
pp. 2507-2510 ◽  
Author(s):  
Pinting Tang ◽  
Jing Zheng ◽  
Jianru Tang ◽  
Dandan Ma ◽  
Weijian Xu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Messenger Rna ◽  
Triple Helix ◽  
Molecular Switch ◽  
Living Cells ◽  
Dna Triple Helix

We demonstrated a gold nanoparticles-integrated programmable triple-helix molecular switch to realize biosensing messenger RNA from in homogenous solutions to living cells.

A novel colorimetric triple-helix molecular switch aptasensor based on peroxidase-like activity of gold nanoparticles for ultrasensitive detection of lead(ii)

RSC Advances ◽  
2015 ◽  
Vol 5 (54) ◽  
pp. 43508-43514 ◽  
Author(s):  
Seyed Mohammad Taghdisi ◽  
Noor Mohammad Danesh ◽  
Parirokh Lavaee ◽  
Ahmad Sarreshtehdar Emrani ◽  
Mohammad Ramezani ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Gold Nanoparticles ◽  
Triple Helix ◽  
Molecular Switch ◽  
Environmental Contaminant ◽  
Ultrasensitive Detection ◽  
Toxic Heavy Metals

Lead (Pb) is a serious environmental contaminant and one of the most toxic heavy metals.

scholarly journals Fluctuating Diffusivity of RNA-Protein Particles: Analogy with Thermodynamics

Entropy ◽  
2021 ◽  
Vol 23 (3) ◽  
pp. 333
Author(s):  
Yuichi Itto
Keyword(s):  
Internal Energy ◽  
Messenger Rna ◽  
Living Cells ◽  
Statistical Fluctuation ◽  
Rna Molecules ◽  
Average Value ◽  
Thermodynamic Entropy ◽  
Laws Of Thermodynamics ◽  
Protein Particles ◽  
Quantity Of Heat

A formal analogy of fluctuating diffusivity to thermodynamics is discussed for messenger RNA molecules fluorescently fused to a protein in living cells. Regarding the average value of the fluctuating diffusivity of such RNA-protein particles as the analog of the internal energy, the analogs of the quantity of heat and work are identified. The Clausius-like inequality is shown to hold for the entropy associated with diffusivity fluctuations, which plays a role analogous to the thermodynamic entropy, and the analog of the quantity of heat. The change of the statistical fluctuation distribution is also examined from a geometric perspective. The present discussions may contribute to a deeper understanding of the fluctuating diffusivity in view of the laws of thermodynamics.

Self-Assembled Growing DNA Tree Mediated by Exosomes for Amplified Imaging of Messenger RNA in Living Cells

2021 ◽  
Author(s):  
Cheng Fang ◽  
Yuming Li ◽  
Song Hu ◽  
Hao Wang ◽  
Xiaoxia Chen ◽  
...  
Keyword(s):  
Messenger Rna ◽  
Living Cells ◽  
Self Assembled

Use of Frog Eggs and Oocytes for the Study of Messenger RNA and its Translation in Living Cells

Nature ◽  
1971 ◽  
Vol 233 (5316) ◽  
pp. 177-182 ◽  
Author(s):  
J. B. GURDON ◽  
C. D. LANE ◽  
H. R. WOODLAND ◽  
G. MARBAIX
Keyword(s):  
Messenger Rna ◽  
Living Cells

scholarly journals Site-specific inhibition ofEcoRI restriction/modification enzymes by a DNA triple helix

1990 ◽  
Vol 18 (1) ◽  
pp. 157-161 ◽  
Author(s):  
Jeffery C. Hanvey ◽  
Mitsuhiro Shimizu ◽  
Robert D. Wells
Keyword(s):  
Triple Helix ◽  
Specific Inhibition ◽  
Site Specific ◽  
Dna Triple Helix ◽  
Restriction Modification

A sensitive SERS assay for detecting proteins and nucleic acids using a triple-helix molecular switch for cascade signal amplification

2014 ◽  
Vol 50 (66) ◽  
pp. 9409-9412 ◽  
Author(s):  
Sujuan Ye ◽  
Yanying Wu ◽  
Wen Zhang ◽  
Na Li ◽  
Bo Tang
Keyword(s):  
Nucleic Acids ◽  
Signal Amplification ◽  
Triple Helix ◽  
Detection System ◽  
Molecular Switch ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Multiple Cycle ◽  
Enhanced Raman Scattering

A sensitive surface-enhanced Raman scattering (SERS) detection system is developed for proteins and nucleic acids based on a triple-helix molecular switch for multiple cycle signal amplification.

A fluorine-doped tin oxide electrode modified with gold nanoparticles for electrochemiluminescent determination of hydrogen peroxide released by living cells

2016 ◽  
Vol 184 (2) ◽  
pp. 603-610 ◽  
Author(s):  
Man Li ◽  
Hongfang Gao ◽  
Xiaofei Wang ◽  
Yufeng Wang ◽  
Honglan Qi ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Gold Nanoparticles ◽  
Tin Oxide ◽  
Living Cells ◽  
Oxide Electrode
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