Redox-responsive host–guest system using redox-active pillar[5]arene containing one benzoquinone unit

2016 ◽  
Vol 52 (38) ◽  
pp. 6479-6481 ◽  
Author(s):  
Tomoki Ogoshi ◽  
Tomohiro Akutsu ◽  
Yasuo Shimada ◽  
Tada-aki Yamagishi
Keyword(s):  
Redox Active ◽  
Redox Responsive ◽  
Guest System

Pillar[5]arene with one benzoquinone formed weak complex with a guest, while pillar[5]arene containing one hydroquinone strongly captured the guest.

scholarly journals Drawing on biology to inspire molecular design: a redox-responsive MRI probe based on Gd(iii)-nicotinamide

2018 ◽  
Vol 54 (92) ◽  
pp. 12986-12989 ◽  
Author(s):  
Michael Harris ◽  
Jacek L. Kolanowski ◽  
Edward S. O’Neill ◽  
Céline Henoumont ◽  
Sophie Laurent ◽  
...  
Keyword(s):  
Molecular Design ◽  
Biologically Inspired ◽  
Redox Active ◽  
Reversible Redox ◽  
Redox Responsive ◽  
Redox Switch

A novel, reversible redox-active MRI probe, GdNR1, has been developed based on the biologically-inspired nicotinimidium redox switch.

Buildup of Redox-Responsive Hybrid from Polyoxometalate and Redox-Active Conducting Oligomer: Its Self-Assemblies with Controllable Morphologies

2017 ◽  
Vol 23 (59) ◽  
pp. 14860-14865 ◽  
Author(s):  
Shan She ◽  
Zehuan Huang ◽  
Panchao Yin ◽  
Aruuhan Bayaguud ◽  
Hongli Jia ◽  
...  
Keyword(s):  
Redox Active ◽  
Redox Responsive

scholarly journals Characterization of Redox-Responsive LXR-Activating Nanoparticle Formulations in Primary Mouse Macrophages

Molecules ◽  
2019 ◽  
Vol 24 (20) ◽  
pp. 3751 ◽  
Author(s):  
Tyler K. T. Smith ◽  
Zaina Kahiel ◽  
Nicholas D. LeBlond ◽  
Peyman Ghorbani ◽  
Eliya Farah ◽  
...  
Keyword(s):  
Potential Candidate ◽  
Beneficial Effects ◽  
Redox Active ◽  
Primary Mouse ◽  
Mouse Macrophages ◽  
Redox Responsive ◽  
Exposure In Vivo ◽  
Abca1 Protein

Activation of the transcription factor liver X receptor (LXR) has beneficial effects on macrophage lipid metabolism and inflammation, making it a potential candidate for therapeutic targeting in cardiometabolic disease. While small molecule delivery via nanomedicine has promising applications for a number of chronic diseases, questions remain as to how nanoparticle formulation might be tailored to suit different tissue microenvironments and aid in drug delivery. In the current study, we aimed to compare the in vitro drug delivering capability of three nanoparticle (NP) formulations encapsulating the LXR activator, GW-3965. We observed little difference in the base characteristics of standard PLGA-PEG NP when compared to two redox-active polymeric NP formulations, which we called redox-responsive (RR)1 and RR2. Moreover, we also observed similar uptake of these NP into primary mouse macrophages. We used the transcript and protein expression of the cholesterol efflux protein and LXR target ATP-binding cassette A1 (ABCA1) as a readout of GW-3956-induced LXR activation. Following an initial acute uptake period that was meant to mimic circulating exposure in vivo, we determined that although the induction of transcript expression was similar between NPs, treatment with the redox-sensitive RR1 NPs resulted in a higher level of ABCA1 protein. Our results suggest that NP formulations responsive to cellular cues may be an effective tool for targeted and disease-specific drug release.

Sub-nanometer expansions of redox responsive polymer films monitored by imaging ellipsometry

Nanoscale ◽  
2014 ◽  
Vol 6 (20) ◽  
pp. 12089-12095 ◽  
Author(s):  
Aysegul Cumurcu ◽  
Xueling Feng ◽  
Lionel Dos Ramos ◽  
Mark A. Hempenius ◽  
Peter Schön ◽  
...  
Keyword(s):  
Thin Films ◽  
Real Time ◽  
Electrochemical Oxidation ◽  
Imaging Ellipsometry ◽  
Oxidation Reduction ◽  
Novel Approach ◽  
Redox Active ◽  
Redox Responsive ◽  
Responsive Polymer

We describe a novel approach to quantitatively visualize sub nm height changes occurring in thin films of redox active polymers upon reversible electrochemical oxidation/reduction in situ and in real-time with electrochemical imaging ellipsometry (EC-IE).

Efficacious redox-responsive gene delivery in serum by ferrocenylated monomeric and dimeric cationic cholesterols

2015 ◽  
Vol 13 (14) ◽  
pp. 4310-4320 ◽  
Author(s):  
Gururaja Vulugundam ◽  
Krishan Kumar ◽  
Paturu Kondaiah ◽  
Santanu Bhattacharya
Keyword(s):  
Gene Delivery ◽  
Gene Transfection ◽  
Redox Active ◽  
Redox Responsive ◽  
Responsive Gene

New redox-active monomeric and dimeric ferrocenylated cationic cholesterols for gene transfection.

A redox-responsive organogel based on a selenium-containing low molecular mass gelator

2020 ◽  
Vol 44 (1) ◽  
pp. 24-28 ◽  
Author(s):  
Haojie Zhang ◽  
Xiuping Lu ◽  
Zhao Chen ◽  
Jianzhong Jiang ◽  
Yukai Chen
Keyword(s):  
Ethyl Acetate ◽  
Molecular Mass ◽  
Active Center ◽  
Redox Active ◽  
Redox Responsive

A redox-responsive low molecular mass gelator (Chol-Se) with selenium as its redox-active center was designed and synthesized. Responsive transformation of Chol-Se in ethyl acetate between the gelation and solution was achieved.

scholarly journals Redox-responsive phosphonite gold complexes in hydroamination catalysis

2019 ◽  
Vol 55 (37) ◽  
pp. 5323-5326 ◽  
Author(s):  
Eva Deck ◽  
Hanna E. Wagner ◽  
Jan Paradies ◽  
Frank Breher
Keyword(s):  
Gold Complexes ◽  
Redox Active ◽  
Redox Responsive ◽  
Very High

Very high activities were observed in the redox-induced hydroamination of alkynes by employing a redox-active gold(i) complex featuring an electron-deficient, terphenyl-substituted phosphonite-based ligand.

Tetranuclear Ru Complex Linked via Redox-Active Azobis(bipyridine) Ligands as a Redox-Responsive Photoswitch

2003 ◽  
Vol 76 (6) ◽  
pp. 1185-1189 ◽  
Author(s):  
Joe Otsuki ◽  
Dong-Mei Li ◽  
Katsuhiko Sato ◽  
Asako Nakagome ◽  
Toshio Takido ◽  
...  
Keyword(s):  
Ru Complex ◽  
Redox Active ◽  
Redox Responsive
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